The author presented experimental data on the influence of technological factors on the quality indexes of tablets based on a cryoliofilized salmonella bacteriophage. The analysis of the technological properties of model granules with such parameters as bulk density, flow ability, vibration compacting index, Hausner index, Сarr's index showed that the fractional composition of the granules should contain no more than 33 % of the pulverized fraction (0,25 mm or less). The granulate, regardless of its fractional composition, has elastic-plastic properties characterizing the strength of the tablets. The influence of the pressing pressure of the cryoliofilized composition tablets with salmonella bacteriophage on the crush strength and disintegration of enteric-soluble tablets was studied. The optimum compression pressure of tablets within 60 mPa of granules with a content of pulp fraction (0.25 mm or less) is not to be higher than 33 %.
