Morphological analyses of NADPH-diaphorase/nitric oxide synthase positive structures in human visual cortex

1994 ◽  
Vol 23 (12) ◽  
pp. 770-782 ◽  
Author(s):  
Hans -Joachim L�th ◽  
Annelies Hedlich ◽  
Heidegard Hilbig ◽  
Ernst Winkelmann ◽  
Bernd Mayer
Parasitology ◽  
2000 ◽  
Vol 120 (1) ◽  
pp. 91-95 ◽  
Author(s):  
N. B. TERENINA ◽  
M. V. ONUFRIEV ◽  
N. V. GULYAEVA ◽  
A. M. LINDHOLM ◽  
M. K. S. GUSTAFSSON

The free radical nitric oxide (NO) is a neuronal messenger which is synthesized from L-arginine and O2 by nitric oxide synthase (NOS). In the synthesis NO and L-citrulline are produced in a stoichiometric 1[ratio ]1 relation. The activity of NOS was analysed in homogenates of the rat tapeworm Hymenolepis diminuta by measuring the formation of L-[3H]citrulline after incubation with L-[3H]arginine. The nature of NOS in H. diminuta was determined by studying the effect of 3 types of NOS inhibitors: (1) L-NAME, (2) EGTA, (3) 7-nitro-indazole. All inhibitors caused a significant but not complete reduction in the formation of L-[3H]citrulline. The results are discussed against the background of nerve cells and fibres positive for NADPH-diaphorase staining in H. diminuta.


Neuron ◽  
1991 ◽  
Vol 7 (4) ◽  
pp. 615-624 ◽  
Author(s):  
David S. Bredt ◽  
Charles E. Glatt ◽  
Paul M. Hwang ◽  
Majid Fotuhi ◽  
Ted M. Dawson ◽  
...  

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