Warm blood cardioplegia reduces the fall in the intracellular concentration of taurine in the ischaemic/reperfused heart of patients undergoing aortic valve surgery

Amino Acids ◽  
1998 ◽  
Vol 15 (4) ◽  
pp. 339-350 ◽  
Author(s):  
R. Ascione ◽  
W. J. Gomes ◽  
G. D. Angelini ◽  
A. J. Bryan ◽  
M. -S. Suleiman
Keyword(s):  
Aortic Valve ◽  
Valve Surgery ◽  
Intracellular Concentration ◽  
Aortic Valve Surgery ◽  
Blood Cardioplegia ◽  
Warm Blood ◽  
Warm Blood Cardioplegia

Intermittent Warm Blood Cardioplegia in Aortic Valve Surgery: An Update

2007 ◽  
pp. 181-188
Author(s):  
M. Saadah Suleiman ◽  
Raimondo Ascione ◽  
Gianni D. Angelini
Keyword(s):  
Aortic Valve ◽  
Valve Surgery ◽  
Aortic Valve Surgery ◽  
Blood Cardioplegia ◽  
Warm Blood ◽  
Warm Blood Cardioplegia

Intermittent Antegrade Warm Blood Cardioplegia in Aortic Valve Replacement

1996 ◽  
Vol 11 (5) ◽  
pp. 348-354 ◽  
Author(s):  
Antonio M. Calafiore ◽  
Giovanni Teodori ◽  
Giovanni Bosco ◽  
Gabriele Di Giammarco ◽  
Giuseppe Vitolla ◽  
...  
Keyword(s):  
Aortic Valve ◽  
Aortic Valve Replacement ◽  
Valve Replacement ◽  
Blood Cardioplegia ◽  
Warm Blood ◽  
Warm Blood Cardioplegia

Abstract 18424: Elective Cardiac Arrest in Isolated Aortic Valve Surgery: Comparison of Blood-cardioplegia versus HTK-Bretschneider Solution in 7005 Consecutive Patients

Circulation ◽  
2015 ◽  
Vol 132 (suppl_3) ◽  
Author(s):  
Alexandro A Hoyer ◽  
Sven Lehmann ◽  
Andreas Oberbach ◽  
Denis A Merk ◽  
Stefan Feder ◽  
...  
Keyword(s):  
Cardiac Arrest ◽  
Aortic Valve ◽  
Valve Surgery ◽  
Aortic Valve Surgery ◽  
Term Survival ◽  
Blood Cardioplegia ◽  
Cold Blood ◽  
Group B ◽  
Cold Blood Cardioplegia

Introduction: Assessing the impact of HTK-Bretschneider solution versus blood-cardioplegia on short- and long-term outcome after isolated aortic valve replacement (AVR). Hypothesis: HTK-Bretschneider is not inferior to Blood-cardioplegia for isolated aortic valve replacement. Methods: Screening of our institutional database revealed 7290 consecutive patients who underwent AVR between 11/1994 and 06/2015. In the majority of patients (n=5998; 83%) antegrade infusion of htk-bretschneider solution (custodiol®) was used for elective cardiac arrest (Group A). Intermittent cold blood-cardioplegia was chosen in 1007 patients (14%; Group B). All preoperative risk-factors were considered for risk-factor analysis influencing outcome. Results: Early mortality was equal between the subgroups (p=0.22). Postoperative complications like pacemaker implantation (p=0.01) or low cardiac output were more likely to occur in group B (p=0.02). Overall long term survival was inferior for patients receiving elective cardiac arrest with cold blood cardioplegia (p<0.001). Cox-regression identified age (HR: 1.063 ; p<0.001), end stage renal disease (ESDR; HR:4.8; p<0.001), history of PCI (HR: 1.3; p=0.03), active infective endocarditis (AIE; HR: 2.1; p<0.001), neurological dysfunction (HR: 1.4; p=0.02), low ejection fraction (EF<30%; HR: 2.5; p<0.001), prior cardiac surgery (HR:1,5; p=0.02) and emergent surgical intervention (HR: 2.5; p<0.001) being highly associated with long term survival and occurring more frequently in group B. Artificial low-risk and high-risk groups showed no differences in longevity depending on cardioplegic solutions (p=0.35). Conclusions: Blood-cardioplegia for elective cardiac arrest seems to be preferred when complex aortic valve surgery is expected. However, HTK-Bretschneider solution yields equivalent longevity to blood-cardioplegia, even after surgery demanding extended cross-clamp times.

Balloon occlusion of the aortic valve for antegrade continuous warm blood cardioplegia

1995 ◽  
Vol 59 (6) ◽  
pp. 1627 ◽  
Author(s):  
Takeshi Miyairi ◽  
Hirotaka Inaba ◽  
Keita Tanaka ◽  
Akira Mizuno
Keyword(s):  
Aortic Valve ◽  
Balloon Occlusion ◽  
Blood Cardioplegia ◽  
Warm Blood ◽  
Warm Blood Cardioplegia

scholarly journals Antegrade Intermittent Cold Cardioplegia in Comparison to Antegrade Intermittent Warm Cardioplegia in Heart Valve Surgery

2020 ◽  
Author(s):  
Haitham Abdel-bakey ◽  
Ahmed Elminshawy ◽  
Ahmed Ghoneim ◽  
Ahmed Taha
Keyword(s):  
Heart Valve ◽  
Valve Surgery ◽  
Controlled Study ◽  
Heart Valve Surgery ◽  
Ischemic Time ◽  
Blood Cardioplegia ◽  
Significant Difference ◽  
Warm Blood ◽  
Cold Cardioplegia ◽  
Warm Blood Cardioplegia

Background: The cardioplegic arrest is essential for motionless and bloodless heart valve surgery. The objective of this work was to compare antegrade cold versus warm blood cardioplegia during valve surgery. Methods: This randomized controlled study included 100 patients who had mitral valve surgery. Patients were randomly assigned into two groups; the warm cardioplegic group (n= 50) and the cold cardioplegic group (n= 50). Study endpoints were creatine kinase myocardial band, lactate dehydrogenase, and troponin levels. Results: There was no significant difference in age and sex between groups (p= 0.51 and 0.56, respectively). Cardiopulmonary bypass was significantly longer in the cold group (85.66 ± 22.9 vs. 72.34 ± 25.09 minutes; P= 0.01); however, there was no difference in ischemic time (p= 0.32). The number of DC shocks given for each patient is less in the warm group with a median of 1.5 (range 1-3 times), while in the cold group, the median was 2 (range 2-4 times); p= 0.02. The amount of blood loss was significantly lower among the warm group (645.4 ± 464.93 ml vs. 404 ± 252.7 P< 0.01). warm group had significantly lower postoperative CK (532.78 ± 249.08 vs. 638.14 ± 344.01 IU/L; P< 0.01), CK-MB (78.64 ± 34.58 vs.  103.18 ± 82.11; P< 0.0.01), LDH level (805.3 ± 322.71 vs. 1060.88 ± 500.94 mg/dl; P< 0.01) and (0.4148 ± 0.226 vs. 0.6404 ± 0.411 ng/ml; P< 0.01).   Conclusion: Antegrade warm blood cardioplegia may provide better myocardial protection during valve surgery compared to the cold cardioplegia. A larger study is recommended.

scholarly journals Cold crystalloid versus warm blood cardioplegia in patients undergoing aortic valve replacement

2018 ◽  
Vol 10 (3) ◽  
pp. 1490-1499 ◽  
Author(s):  
Paolo Nardi ◽  
Sara R. Vacirca ◽  
Marco Russo ◽  
Dionisio F. Colella ◽  
Carlo Bassano ◽  
...  
Keyword(s):  
Aortic Valve ◽  
Aortic Valve Replacement ◽  
Valve Replacement ◽  
Blood Cardioplegia ◽  
Warm Blood ◽  
Warm Blood Cardioplegia
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