scholarly journals On the statistical evaluation of dose-response functions

1974 ◽  
Vol 11 (1) ◽  
pp. 1-13 ◽  
Author(s):  
A. M. Kellerer ◽  
J. Brenot
2019 ◽  
Vol 168 ◽  
pp. 108944 ◽  
Author(s):  
Gianluca Pastorelli ◽  
Shuo Cao ◽  
Irena Kralj Cigić ◽  
Costanza Cucci ◽  
Abdelrazek Elnaggar ◽  
...  

2017 ◽  
Vol 62 (12) ◽  
pp. 5131-5148 ◽  
Author(s):  
Hui Khee Looe ◽  
Björn Delfs ◽  
Daniela Poppinga ◽  
Dietrich Harder ◽  
Björn Poppe

2018 ◽  
Vol 63 (19) ◽  
pp. 195002 ◽  
Author(s):  
Björn Delfs ◽  
Daniela Poppinga ◽  
Ann-Britt Ulrichs ◽  
Ralf-Peter Kapsch ◽  
Dietrich Harder ◽  
...  

2000 ◽  
Vol 20 (11) ◽  
pp. 4226-4232 ◽  
Author(s):  
Pier Vincenzo Piazza ◽  
Véronique Deroche-Gamonent ◽  
Françoise Rouge-Pont ◽  
Michel Le Moal

1962 ◽  
Vol 40 (11) ◽  
pp. 1473-1476 ◽  
Author(s):  
C. J. Pfeiffer ◽  
G. H. Gass

The present investigation has demonstrated that administration of caffeine alkaloid (6.25 mg/kg, 25 mg/kg, and 100 mg/kg) by stomach tube induces acute gastric ulcers in the fundus, pylorus, and antrum of fasting male and female rats. The ulcers are histologically characterized as superficial erosions of the glandular mucosa. Statistical evaluation of ulcer indices indicated a linear, log dose–response relationship for caffeine alkaloid, and a similar ulcerogenic effect in both male and female rats.


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