Possible role of GABA in the development of tolerance to alcohol

1977 ◽  
Vol 33 (4) ◽  
pp. 496-498 ◽  
Author(s):  
G. J. Leitch ◽  
D. J. Backes ◽  
F. S. Siegman ◽  
G. D. Guthrie
Keyword(s):  
Development Of Tolerance

scholarly journals Role of L -arginine in the vascular actions and development of tolerance to nitroglycerin

2000 ◽  
Vol 130 (2) ◽  
pp. 211-218 ◽  
Author(s):  
Gamal Abou-Mohamed ◽  
Wayne H Kaesemeyer ◽  
Ruth B Caldwell ◽  
Robert W Caldwell
Keyword(s):  
Development Of Tolerance

Role of uptake of [14C]valine into protein in the development of tolerance to diisopropylphosphorofluoridate (DFP) toxicity

1986 ◽  
Vol 84 (3) ◽  
pp. 551-560 ◽  
Author(s):  
Ramesh C. Gupta ◽  
Wolf-D. Dettbarn
Keyword(s):  
Development Of Tolerance

scholarly journals ROLE OF THE ENDOCANNABINOID SYSTEM IN THE DEVELOPMENT OF TOLERANCE TO ALCOHOL

2004 ◽  
Vol 40 (1) ◽  
pp. 15-24 ◽  
Author(s):  
BALAPAL S. BASAVARAJAPPA ◽  
BASALINGAPPA L. HUNGUND
Keyword(s):  
Endocannabinoid System ◽  
Development Of Tolerance

Role of dose order in the development of tolerance to effects of cocaine on schedule-controlled behavior in pigeons

2002 ◽  
Vol 163 (3-4) ◽  
pp. 302-309 ◽  
Author(s):  
Michelle L. Miller ◽  
Marc N. Branch
Keyword(s):  
Development Of Tolerance

Role of the hepatic function in the development of the pyrogenic tolerance to muramyl dipeptide

2001 ◽  
Vol 281 (1) ◽  
pp. R162-R169 ◽  
Author(s):  
Márcia E. S. Ferreira ◽  
Márcio M. Coelho ◽  
Irene R. Pelá
Keyword(s):  
Protein Synthesis ◽  
Intraperitoneal Injection ◽  
Specific Inhibitor ◽  
Muramyl Dipeptide ◽  
Hepatic Function ◽  
Hepatic Protein Synthesis ◽  
Development Of Tolerance

We have demonstrated that the hepatic function may have an important role in the development of tolerance to the pyrogenic effect induced by endotoxin. To further investigate if the role of the hepatic function in the development of tolerance also extends to that induced by other pyrogenic stimuli, we investigated the effect of galactosamine, a specific inhibitor of the hepatic protein synthesis, on the development of tolerance to the pyrogenic effect induced by muramyl dipeptide (MDP) in rats. Pyrogenic tolerance was observed after the second intravenous or intraperitoneal injection of MDP (500 μg/kg), 24 h after the first injection, similar to what was observed with endotoxin. Pyrogenic tolerance was abolished when galactosamine (300 mg/kg ip) was injected simultaneously with MDP (500 μg/kg iv) on the first day. When uridine (600 mg/kg ip) was administered simultaneously with galactosamine (300 mg/kg ip) and the first injection of MDP (500 μg/kg ip), pyrogenic tolerance was again observed after the second injection of the peptidoglycan. In conclusion, the hepatic function may not be important only for the development of tolerance to endotoxin, but also to a totally different pyrogenic stimulus such as MDP.

scholarly journals The role of NTS2 in the development of tolerance to NT69L in mouse models for hypothermia and thermal analgesia

2011 ◽  
Vol 224 (2) ◽  
pp. 344-349 ◽  
Author(s):  
Kristin E. Smith ◽  
Mona Boules ◽  
Katrina Williams ◽  
Abdul H. Fauq ◽  
Elliott Richelson
Keyword(s):  
Mouse Models ◽  
Development Of Tolerance

The role of arginine vasopressin in the development of tolerance to ethanol in normal and Brattleboro rats

Peptides ◽  
1988 ◽  
Vol 9 ◽  
pp. 193-200 ◽  
Author(s):  
Dennis L. Hjeresen ◽  
Deborah J. Brief ◽  
Diane L. Amend ◽  
Daniel M. Dorsa ◽  
Stephen C. Woods
Keyword(s):  
Arginine Vasopressin ◽  
Brattleboro Rats ◽  
Tolerance To Ethanol ◽  
Development Of Tolerance

P.6.d.005 Evaluation of the role of central adenosine A1 and A2a receptors in the development of tolerance to morphine analgesia in rats

2010 ◽  
Vol 20 ◽  
pp. S590-S591
Author(s):  
M. Charkhpour ◽  
A. Parvizpur ◽  
F. Ebrahimi ◽  
P. Talebi ◽  
H. Samadi ◽  
...  
Keyword(s):  
Morphine Analgesia ◽  
A2a Receptors ◽  
Adenosine A1 ◽  
Development Of Tolerance
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