Presymptomatic diagnosis of familial adenomatous polyposis coli

1994 ◽  
Vol 37 (7) ◽  
pp. 700-707 ◽  
Author(s):  
Jae-Gahb Park ◽  
Hye-Jung Han ◽  
Myung-Soo Kang ◽  
Yusuke Nakamura

2010 ◽  
Vol 53 (10) ◽  
pp. 1381-1387 ◽  
Author(s):  
Petra Ganschow ◽  
Ulrike Pfeiffer ◽  
Ulf Hinz ◽  
Christine Leowardi ◽  
Christian Herfarth ◽  
...  


1993 ◽  
Vol 13 (2) ◽  
pp. 133-141 ◽  
Author(s):  
I. Uzoaru ◽  
F. J. Podbielski ◽  
P. Chou ◽  
J. G. Raffensperger ◽  
F. Gonzalez-Crussi


2009 ◽  
Vol 16 (4) ◽  
pp. 571-574 ◽  
Author(s):  
Yukiyasu Okamura ◽  
Atsuyuki Maeda ◽  
Kazuya Matsunaga ◽  
Hideyuki Kanemoto ◽  
Hiroyoshi Furukawa ◽  
...  


Author(s):  
Richard Wismayer

Introduction: Familial adenomatous polyposis (FAP) is a rare diagnosis in East Africa. The author reports a case of a 21 year old gentleman presenting with occasional passage of blood stained stool, and found to have familial adenomatous polyposis coli. This is followed by a literature review on the pathogenesis, clinical features and treatment options of FAP in East Africa. Presentation of Case: This patient presented with a strong family history of familial adenomatous polyposis, blood stained stool and a rectal mass. A total proctocolectomy and ileoanal anastomosis was carried out. The postoperative course of this patient was uneventful. Discussion: The typical gross pathological and histological features of familial adenomatous polyposis and rectal adenocarcinoma were seen on the resected colorectal specimen. In addition this study reviews the literature regarding the clinical presentation, pathological characteristics and treatment options of familial adenomatous polyposis coli. Conclusion: FAP should always be considered in a young patient presenting with a strong family history of CRC. Colonoscopy should be performed on these patients with early symptoms and those patients with a strong family history of FAP. In East Africa, the creation of a permanent stoma is unacceptable and therefore a proctocolectomy and Brooke ileostomy will not be a desirable option in a young patient in this part of the world.



1997 ◽  
Vol 40 (6) ◽  
pp. 679-684 ◽  
Author(s):  
Alexander M. Nikitin ◽  
Victor K. Obukhov ◽  
Yuri Y. Chubarov ◽  
Andrew V. Jakushin


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