TGFβ and bFGF synthesis and localization in Dupuytren's disease (nodular palmar fibromatosis) relative to cellular activity, myofibroblast phenotype and oncofetal variants of fibronectin

1995 ◽  
Vol 27 (12) ◽  
pp. 1014-1020 ◽  
Author(s):  
A. Berndt ◽  
H. Kosmehl ◽  
U. Mandel ◽  
U. Gabler ◽  
Xinmei Luo ◽  
...  
2020 ◽  
Vol 25 (04) ◽  
pp. 513-514
Author(s):  
Sebastian Hediger ◽  
Sylvia Höller ◽  
Konrad Mende

We present the case of a severe and long-standing Dupuytren’s contracture where intraoperatively an ossified nodule was encountered within the diseased tissue. Histologically palmar fibromatosis in contact with cartilaginous tissue with central ossification could be confirmed, compatible with metaplasia. Our finding suggests that metaplastic activity inherent to longstanding, severely diseased Dupuytren’s tissue can lead to heterotopic ossification.


2007 ◽  
Vol 79 (12) ◽  
Author(s):  
Jerzy Jabłecki ◽  
Leszek Kaczmarzyk ◽  
Adam Domanasiewicz ◽  
Janusz Kaczmarzyk

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