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Author(s):  
Valentin Gabelmann ◽  
Felix Grabs ◽  
Simon Diestelmeier ◽  
Felix Heindl ◽  
Markus Vosseler ◽  
...  

Non-bacterial thrombotic endocarditis (NBTE) is a rare finding, which is mostly associated with malignant diseases leading to hypercoagulability. We report the case of a severe quadruple valve non-bacterial thrombotic endocarditis in a patient with clear cell cervical cancer.


2022 ◽  
Vol 2022 ◽  
pp. 1-4
Author(s):  
Tamilselvi Sethupathy ◽  
Madhankumar Madathupalayam ◽  
Krithika Arun Prasad

Uterine leiomyoma is a common benign uterine tumor of women in the reproductive age group. Although the common symptoms of leiomyoma are menorrhagia and dysmenorrhoea, this patient presenting as a near collapse is a rare finding. The patient presented with abdominal pain and worsening anemia within a span of hours and hypotension, tachycardia, and tachypnoea needing urgent surgical intervention and blood transfusion and intensive care support is relatively rare. Though every effort to know the exact cause of intraperitoneal hemorrhage in this patient was taken, the rarer diagnosis of capsular venous rupture was not identified prior to surgical intervention. Initially, laparoscopy was introduced first to identify the cause of massive hemorrhage; the approach was changed to open myomectomy keeping in mind the general condition of the patient. Hence, for any patient with a prior diagnosis of myoma with hemodynamic instability, the rarer diagnosis of leiomyomatous capsular venous erosion should be a differential diagnosis to aid in the appropriate management of the women. The team of interdisciplinary expertise will definitely improve the outcomes in such cases.


EMJ Oncology ◽  
2022 ◽  
Author(s):  
Sajjad Ali Khan ◽  
M. Mustansir Mehdi Khan ◽  
Matiullah Kamin ◽  
Azra Rizwan

Background: Concurrent thyroid cancer and hyperthyroidism is a rare finding. The frequency of this association is very variable. A rare case of papillary thyroid cancer associated with hyperthyroidism is described here. Case: A 49-year-old male presented to the authors’ outpatient clinic with complaints of a painless left-sided anterior neck swelling that had persisted for the past 8 months. He also reported weight loss for the same duration. The anterolateral swelling was non-tender, asymmetrical, mobile, and rubbery. Investigations: Biochemical analysis confirmed hyperthyroidism. Ultrasound examination of the neck showed a well-defined, solid, and cystic lesion in the left lobe and isthmus of thyroid gland. The solid portion had few specks of calcification. A radioactive thyroid scan showed increased tracer uptake in the left lobe. Papillary carcinoma of thyroid origin was discovered after fine-needle aspiration of the left anterior cervical lymph node. After preparation, a total thyroidectomy was done. Examination of histopathology confirmed papillary thyroid carcinoma. Treatment: Following radioactive thyroid ablation, the patient was started on suppressive doses of thyroxine daily. Conclusion: Although thyroid cancer with hyperthyroidism is a rare finding, it should not be disregarded. To avoid missing this unusual yet uncommon discovery, a detailed history and physical examination should be performed, as well as all required investigations.


2021 ◽  
Vol 11 (1) ◽  
pp. 158
Author(s):  
Juan García-Bernalt Diego ◽  
Pedro Fernández-Soto ◽  
Juan Luis Muñoz-Bellido ◽  
Begoña Febrer-Sendra ◽  
Beatriz Crego-Vicente ◽  
...  

Detection of SARS-CoV-2 is routinely performed in naso/oropharyngeal swabs samples from patients via RT-qPCR. The RT-LAMP technology has also been used for viral RNA detection in respiratory specimens with both high sensitivity and specificity. Recently, we developed a novel RT-LAMP test for SARS-CoV-2 RNA detection in nasopharyngeal swab specimens (named, N15-RT-LAMP) that can be performed as a single-tube colorimetric method, in a real-time platform, and as dry-LAMP. To date, there has been very little success in detecting SARS-CoV-2 RNA in urine by RT-qPCR, and the information regarding urine viral excretion is still scarce and not comprehensive. Here, we tested our N15-RT-LAMP on the urine of 300 patients admitted to the Hospital of Salamanca, Spain with clinical suspicion of COVID-19, who had a nasopharyngeal swab RT-qPCR-positive (n = 100), negative (n = 100), and positive with disease recovery (n = 100) result. The positive group was also tested by RT-qPCR for comparison to N15-RT-LAMP. Only a 4% positivity rate was found in the positive group via colorimetric N15-RT-LAMP and 2% via RT-qPCR. Our results are consistent with those obtained in other studies that the presence of SARS-CoV-2 RNA in urine is a very rare finding. The absence of SARS-CoV-2 RNA in urine in the recovered patients might suggest that the urinary route is very rarely used for viral particle clearance.


Cureus ◽  
2021 ◽  
Author(s):  
Mansoor Zafar ◽  
Abdul Wahab Paracha ◽  
Muteeb Ashraf ◽  
Tila Muhammad ◽  
Mark Whitehead ◽  
...  

2021 ◽  
Author(s):  
Pontus Westerström ◽  
Ulrik Bak Dragsted

Abstract Purpose (stating the main purposes and research question)Vibrio cholerae is classified in O-antigen polysaccharide outer membrane properties where O1 and O139 are strains that cause pandemics and epidemics while non-O1/non-O139 usually cause mild disease. The dynamic evolution of Vibrio cholerae involves new virulence factors through horizontal gene transfer and formerly nontoxigenic serogroups are being reported as causing increasingly severe forms of human disease. Our purpose was to investigate serogroup and virulence factors in one imported isolate from Vietnam and compare these to virulence factors seen in different strains of Vibrio cholerae.MethodsWe have serotyped one isolate of imported Vibrio cholerae from Vietnam to Denmark and performed whole genome sequencing to identify known virulence genes. ResultsWe have identified virulence factors in our isolate that are recently discovered and one toxin, MakA, has not previously been reported from an Asian strain. The isolate was found to be a serogroup non-O1/non-O139 strain, however, sequence analysis gave a 96, 6% ID match of the wbfZ gene, stipulating our isolate to belong to either serogroup O22 or O139. ConclusionsLooking at the combination of virulence factors of the isolate we suggest the finding of a rough variant of a nontoxigenic Vibrio cholerae O139 rather than a O22 serogroup version. This is a rare finding in a clinical isolate.


2021 ◽  
pp. 014556132110533
Author(s):  
Sarantis Blioskas ◽  
Iordanis Konstantinidis ◽  
Ioannis Antoniadis ◽  
Anastasia Kypriotou ◽  
Prodromos Hytiroglou ◽  
...  

Significance Statement: Primary middle ear inverted papilloma is an exceedingly rare finding posing a diagnostic challenge, as symptomatology often mimics common clinical entities like serous otitis media. Clinical and radiological findings are not specific, whilst high recurrence rates, local destruction, and potential malignant transformation constitute an overall demanding surgical challenge, requiring aggressive procedures. We report the case of a primary inverted papilloma of the middle ear, discussing diagnostic and therapeutic issues.


2021 ◽  
Vol 108 (Supplement_8) ◽  
Author(s):  
Christian Gröger ◽  
Lena Kundel ◽  
Hardwig Riediger

Abstract Aim Repair of inguinal hernia is one of the most common operations in general surgery in industrialized countries. Isolated spermatic cord liposarcoma is a very rare soft tissue tumor. Despite standardized diagnostic algorithms for inguinal hernia, it could be difficult to predict such a rare finding. Material and Methods We report a case of inadvertent inguinal liposarcoma excision during hernia surgery in a 72-year-old male patient. Except for polyposis coli there were no further illnesses. Results After a minimal invasive transabdominal preperitoneal (TAPP) repair of a symptomatic inguinal hernia last year a persistent scrotal swelling developed. Computed tomography (CT) showed a protrusion of fatty tissue into the scrotal sac. Diagnosis of scrotal hernia was made. We performed an open Lichtenstein procedure. The final pathologic examination revealed a highly differentiated liposarcoma. Staging was completed and the case was presented to a multidisciplinary sarcoma tumor board at our institution. As recommended, a inguinal reoperation was performed with wide excision. Conclusions Although a very rare condition, spermatic cord liposarcoma should be considered as a possible differential diagnosis for inguinal hernia surgery.


2021 ◽  
Vol 50 (10) ◽  
pp. 3153-3158
Author(s):  
Veryl Hasan ◽  
Dian Samitra ◽  
Maheno S. Widodo ◽  
Peter Gausmann

A single specimen of a bull shark Carcharhinus leucas (Müller & Henle 1839) with c. 102 cm of total length was landed and photographed on 25 March 2019 in Sungai Mawai Lama, about 25 km inland, Kota Tinggi District, Johor, Peninsular Malaysia. This rare finding represents only the second record of C. leucas in inland Peninsular Malaysia. This shark was identified as C. leucas by the snout much shorter than the width of mouth and bluntly rounded, first dorsal fin triangular, rearward sloping, originating over or slightly behind pectoral insertion, second dorsal fin much smaller than the first dorsal fin (< 3.1:1), and lack of an interdorsal ridge. The coloration of fresh specimen: greyish back and white belly, the dark coloration on the tip of the caudal fins and second dorsal fin. This species is currently listed as a vulnerable species based on the IUCN Red List Status. Further study and monitoring are needed to assess the possibility of the importance of Sungai Mawai Lama as critical habitat of C. leucas.


2021 ◽  
Vol 8 (5) ◽  
pp. 01-04
Author(s):  
Aiman Rahmani ◽  
Zohra Ashraf Siwji ◽  
Alya Talib AlBlooshi ◽  
Moustafa Hamchou

Although inguinal hernias are a common finding in premature infants, it is usually caused by the protrusion of the bowel through a persistent patent processus vaginalis. However, acute appendicitis in association with an inguinal hernia in this age group is a rare finding. This type of hernia is referred to as an Amyand hernia.


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