Changes in bone mineral density (BMD) and total bone mineral content (BMC) in prepubertal children with marked short stature secondary to chronic renal failure (CRF): Effects of biosynthetic growth hormone (rhGH) therapy

1996 ◽  
Vol 6 (S1) ◽  
pp. 286-286
Author(s):  
P. Gunzler ◽  
R. Lanes ◽  
N. Orta ◽  
M. Bosquez ◽  
R. Scovino ◽  
...  
Keyword(s):  
Bone Mineral Density ◽  
Growth Hormone ◽  
Renal Failure ◽  
Chronic Renal Failure ◽  
Bone Mineral ◽  
Mineral Content ◽  
Mineral Density ◽  
Rhgh Therapy ◽  
Prepubertal Children ◽  
Total Bone Mineral Content

Bone mineral density, bone metabolism and body composition of children with chronic renal failure, with and without growth hormone treatment

1998 ◽  
Vol 49 (5) ◽  
pp. 665-672 ◽  
Author(s):  
Annemieke M. Boot ◽  
Jeroen Nauta ◽  
Maria C. J. W De Jong ◽  
Jaap W. Groothoff ◽  
Marc R. Lilien ◽  
...  
Keyword(s):  
Bone Mineral Density ◽  
Growth Hormone ◽  
Renal Failure ◽  
Body Composition ◽  
Chronic Renal Failure ◽  
Bone Metabolism ◽  
Bone Mineral ◽  
Growth Hormone Treatment ◽  
Hormone Treatment ◽  
Mineral Density

Abstract P615: Stress-Induced Changes in Total Bone Mineral Content and Total Bone Mineral Density due to Activation of the Renin-Angiotensin-Aldosterone System in Adolescent Females

Hypertension ◽  
2016 ◽  
Vol 68 (suppl_1) ◽  
Author(s):  
Vishwajeeth Pasham ◽  
Deborah Stewart ◽  
Laura Carbone ◽  
Gregory A Harshfield
Keyword(s):  
Bone Mineral Density ◽  
Bone Mineral Content ◽  
Bone Metabolism ◽  
Bone Mineral ◽  
Mineral Content ◽  
Mineral Density ◽  
Renin Angiotensin Aldosterone System ◽  
Total Bone Mineral Density ◽  
Total Bone Mineral Content ◽  
The Relationship

Background: Previous literature has shown a strong negative effect of angiotensin II (ANGII) on bone metabolism within mouse models. Additionally, psychological stress has been associated with activation of the renin-angiotensin-aldosterone system (RAAS). Stress has also been related to lower total bone mineral density (TBMD). However, there is controversy in the literature examining the relationship between the RAAS and bone metabolism within humans and stress has not been considered as a direct link between these systems. Purpose: We aimed to examine the relationship between stress-induced RAAS activation and TBMD and total bone mineral content (TBMC). Methods: Participants were placed on a sodium controlled diet for three days. Participants then underwent two hours rest, one hour mental stressor, and two hours recovery with hourly collections of blood/urine samples. Renin, ANGII, aldosterone, TBMD and TBMC were measured. Results: This study recruited 586 adolescents (mean age 16±1.116) with 51% women and 62% African-American and 38% Caucasian. Overall, relationships were observed between ANGII and aldosterone, and TBMC and TBMD controlling for age, race, and BMI. During stress, aldosterone was related to TBMD (r=-.150, p<0.05) and ANGII was related to TBMC (r=-.156, p<0.05) and TBMD (r=-.139, p<0.05). When comparing males and females, only females demonstrated a relationship between TBMC and ANGII in response to stress (stress: r=-.229, p<0.05; post-stress: r=-.277, p<0.01) and between aldosterone and TBMC (stress: r=-.199, p<0.05) and TBMD (stress: r=-.250, p<0.01). Renin was not significantly correlated with TBMD nor TBMC in any population. Conclusion/Interpretations: These data suggest that stress-induced RAAS activation may be associated with lower TBMD and TBMC in girls. Despite small correlations, consistency across multiple measures of RAAS activation being apparent in adolescents is significant. This observation may indicate that stress activation of RAAS contributes to bone remodeling in early life.

Treatment with growth hormone and IGF-I in growing rats increases bone mineral content but not bone mineral density

2009 ◽  
Vol 10 (9) ◽  
pp. 1352-1358 ◽  
Author(s):  
Harold N. Rosen ◽  
Vicki Chen ◽  
Antonio Cittadini ◽  
Susan L. Greenspan ◽  
Pamela S. Douglas ◽  
...  
Keyword(s):  
Bone Mineral Density ◽  
Growth Hormone ◽  
Bone Mineral Content ◽  
Bone Mineral ◽  
Mineral Content ◽  
Mineral Density ◽  
Growing Rats ◽  
Igf I

scholarly journals CHANGES IN BONE MINERAL DENSITY, GROWTH VELOCITY AND RENAL FUNCTION IN UREMIC PREPUBERTAL CHILDREN TREATED WITH GROWTH HORMONE

1995 ◽  
Vol 38 (4) ◽  
pp. 622-622
Author(s):  
R Langs ◽  
P Gunczler ◽  
N Orta ◽  
Z M Bosque ◽  
R Scovino ◽  
...  
Keyword(s):  
Bone Mineral Density ◽  
Growth Hormone ◽  
Renal Function ◽  
Bone Mineral ◽  
Growth Velocity ◽  
Mineral Density ◽  
Prepubertal Children ◽  
Density Growth

Bone histomorphometric analysis in forty pre-dialysis chronic renal failure (PDRF) patients with low bone mineral density

Bone ◽  
1996 ◽  
Vol 19 (3) ◽  
pp. 149
Author(s):  
R. Lobäo ◽  
A. Carvalho ◽  
L. Cuppari ◽  
V. Jorgetti ◽  
J.G. Vieira ◽  
...  
Keyword(s):  
Bone Mineral Density ◽  
Renal Failure ◽  
Chronic Renal Failure ◽  
Bone Mineral ◽  
Histomorphometric Analysis ◽  
Mineral Density ◽  
Low Bone Mineral Density

Bone mineral density in children with chronic renal failure

2007 ◽  
Vol 22 (1) ◽  
pp. 121-127 ◽  
Author(s):  
Simon Waller ◽  
Deborah Ridout ◽  
Lesley Rees
Keyword(s):  
Bone Mineral Density ◽  
Renal Failure ◽  
Chronic Renal Failure ◽  
Bone Mineral ◽  
Mineral Density

The effect of RANKL and OPG on bone mineral density in pre-dialysis chronic renal failure

2009 ◽  
Vol 71 (06) ◽  
pp. 652-659 ◽  
Author(s):  
A. Fahrleitner-Pammer ◽  
H. Dobnig ◽  
H.P. Dimai ◽  
H. Holzer ◽  
T. Benesch ◽  
...  
Keyword(s):  
Bone Mineral Density ◽  
Renal Failure ◽  
Chronic Renal Failure ◽  
Bone Mineral ◽  
Mineral Density

Annual change in bone mineral density in predialysis patients with chronic renal failure: significance of a decrease in serum 1,25-dihydroxy-vitamin D

2006 ◽  
Vol 25 (1) ◽  
pp. 74-79 ◽  
Author(s):  
Naoko Obatake ◽  
Eiji Ishimura ◽  
Takao Tsuchida ◽  
Kaname Hirowatari ◽  
Hiroshi Naka ◽  
...  
Keyword(s):  
Bone Mineral Density ◽  
Vitamin D ◽  
Renal Failure ◽  
Chronic Renal Failure ◽  
Bone Mineral ◽  
Annual Change ◽  
Mineral Density
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