A new method for continuous registration of respiratory quotient and substrate uptake in a working rat heart preparation

1982 ◽  
Vol 394 (S1) ◽  
pp. R15-R15
Author(s):  
J. F. Hütter ◽  
H. M. Piper ◽  
P. G. Spieckermann
1992 ◽  
Vol 54 (5) ◽  
pp. 915-920 ◽  
Author(s):  
Todd L. Demmy ◽  
George J. Magovern ◽  
Race L. Kao

1991 ◽  
Vol 59 (4) ◽  
pp. 1053-1068 ◽  
Author(s):  
J. Wondergem ◽  
A. Van Der Laarse ◽  
F.J.M. Van Ravels ◽  
A.-M. Van Wermeskerken ◽  
H.R. Verhoeve ◽  
...  

1979 ◽  
Vol 57 (4) ◽  
pp. 428-431 ◽  
Author(s):  
Robert L. Rodgers ◽  
Joanne I. Moore ◽  
K. Roger Hornbrook

The ionophore X-537A increased heart rate and contractility of the isolated, working rat heart preparation. The increased heart rate appeared to be caused solely by release of catecholamines as the response was completely eliminated by reserpine pretreatment or addition of propranolol to the perfusate. The inotropic response, however, had an apparent catecholamine-independent component as neither propranolol, nor propranolol in combination with phentolamine, completely eliminated the inotropic response to X-537A. On the other hand, reserpine pretreatment did abolish the inotropic effect of the ionophore but this action appeared to be a nonspecific one as the responses to norepinephrine and to CaCl2 were substantially diminished.


1992 ◽  
Vol 267 (6) ◽  
pp. 3758-3763 ◽  
Author(s):  
T.L. Broderick ◽  
H.A. Quinney ◽  
G.D. Lopaschuk

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