Cell volume changes affect gluconeogenesis in the perfused liver of the catfishClarias batrachus

2004 ◽  
Vol 29 (3) ◽  
pp. 337-347 ◽  
Author(s):  
Carina Goswami ◽  
Shritapa Datta ◽  
Kuheli Biswas ◽  
Nirmalendu Saha
Keyword(s):  
Cell Volume ◽  
Perfused Liver ◽  
Volume Changes

Influence of cell volume changes on autophagic proteolysis in the perfused liver of air-breathing walking catfish (Clarias batrachus)

2009 ◽  
Vol 311A (2) ◽  
pp. 115-124 ◽  
Author(s):  
Kuheli Biswas ◽  
James L. Khongsngi ◽  
Dieter Häussinger ◽  
Nirmalendu Saha
Keyword(s):  
Cell Volume ◽  
Clarias Batrachus ◽  
Perfused Liver ◽  
Volume Changes ◽  
Air Breathing

Liver cell hydration and integrin signaling

2021 ◽  
Vol 0 (0) ◽  
Author(s):  
Michele Bonus ◽  
Dieter Häussinger ◽  
Holger Gohlke
Keyword(s):  
Cell Volume ◽  
Liver Cell ◽  
Cell Function ◽  
The Other ◽  
Signaling Cascades ◽  
Integrin Signaling ◽  
Volume Changes ◽  
The One ◽  
And Oxidative Stress

Abstract Liver cell hydration (cell volume) is dynamic and can change within minutes under the influence of hormones, nutrients, and oxidative stress. Such volume changes were identified as a novel and important modulator of cell function. It provides an early example for the interaction between a physical parameter (cell volume) on the one hand and metabolism, transport, and gene expression on the other. Such events involve mechanotransduction (osmosensing) which triggers signaling cascades towards liver function (osmosignaling). This article reviews our own work on this topic with emphasis on the role of β1 integrins as (osmo-)mechanosensors in the liver, but also on their role in bile acid signaling.

scholarly journals Molecular mechanisms of regulation of fast-inactivating voltage-dependent transient outward K+current in mouse heart by cell volume changes

2005 ◽  
Vol 568 (2) ◽  
pp. 423-443 ◽  
Author(s):  
Guan-Lei Wang ◽  
Ge-Xin Wang ◽  
Shintaro Yamamoto ◽  
Linda Ye ◽  
Heather Baxter ◽  
...  
Keyword(s):  
Cell Volume ◽  
Molecular Mechanisms ◽  
Mouse Heart ◽  
Volume Changes ◽  
Voltage Dependent ◽  
K Current

Water permeability of alveolar macrophages

1986 ◽  
Vol 251 (4) ◽  
pp. C524-C528 ◽  
Author(s):  
R. A. Garrick ◽  
T. G. Polefka ◽  
W. O. Cua ◽  
F. P. Chinard
Keyword(s):  
Cell Volume ◽  
Alveolar Macrophages ◽  
Permeability Coefficient ◽  
High Ratio ◽  
Volume Changes ◽  
Membrane Pores ◽  
Linear Relationships ◽  
Diffusional Permeability ◽  
Water Passage ◽  
Suspended Cells

The hydraulic conductivity coefficient (Lp) of alveolar macrophages, recovered by lavage from dog lungs, was determined by following volume changes induced by changes of nonpermeating solute concentrations of suspending fluid as a function of time at 20 degrees C. The volume changes were monitored as changes in absorbance of the suspended cells at 600 nm. Cell surface area was calculated from cell volume and diameter. Linear relationships between cell volume and solution osmolality changes were found over the range of 320-520 mosmol/kg; beyond these ranges the macrophages did not respond with swelling or shrinking. Lp and the filtration coefficient (Pf) were calculated from the total volume change over time. At 20 degrees C these were, respectively, 15.7 X 10(-10) cm X cmH2O-1 X s-1 and 217 X 10(-5) cm/s. Comparison of Pf and the diffusional permeability coefficient (Pd) for water of 70 X 10(-5) cm/s, yields a Pf-to-Pd ratio of 3.1. The hypothesis of water passage through aqueous membrane pores is compatible with these data. However, diffusion of water in the glycocalyx of the pericellular domain could be restricted. Pd would then be underestimated, and a falsely high ratio would be calculated. We have no evidence to support this possibility.

scholarly journals AQP4e-Based Orthogonal Arrays Regulate Rapid Cell Volume Changes in Astrocytes

2017 ◽  
Vol 37 (44) ◽  
pp. 10748-10756 ◽  
Author(s):  
Marjeta Lisjak ◽  
Maja Potokar ◽  
Boštjan Rituper ◽  
Jernej Jorgačevski ◽  
Robert Zorec
Keyword(s):  
Cell Volume ◽  
Orthogonal Arrays ◽  
Volume Changes
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