scholarly journals Primary squamous cell carcinoma of the submandibular salivary gland

2004 ◽  
Vol 56 (2) ◽  
pp. 125-126
Author(s):  
G. Mallikarjuna Rao ◽  
S. V. Ranga Reddy ◽  
M. Janaki ◽  
K. Lakshmi Reddy
Rare Tumors ◽  
2020 ◽  
Vol 12 ◽  
pp. 203636132097352
Author(s):  
Silvia Mezi ◽  
Giulia Pomati ◽  
Andrea Botticelli ◽  
Francesca De Felice ◽  
Daniela Musio ◽  
...  

Primary squamous cell carcinoma of salivary gland (SCG) is an extremely rare type of malignant salivary gland tumor, which in turn results in scarcity of data available regarding both its treatment and associated genetic alterations. A retrospective analysis of 12 patients with primary SCG was conducted, along with analysis of the association between treatment, clinical/pathological characteristics, and outcomes. Most patients (8) were staged IVa, with the majority of them (10) having G3 fast growing cancer. Local and systemic recurrence were reported in only three out of nine parotid cases (0 out of 2 submandibular SCGs). In two out of eight patients local relapse occurred after integrated treatment, while recurrence occurred in two out of three patients undergoing exclusive surgery. Five patients eventually died. Treatment of resectable disease must be aggressive and multimodal, with achievement of loco-regional control in order to reduce rate of recurrence and improve outcomes. Metastatic disease would require a therapeutic strategy tailored to the molecular profile in order to improve the currently disappointing results.


2014 ◽  
Vol 18 (2) ◽  
pp. 299 ◽  
Author(s):  
Vardendra Manvikar ◽  
Surekha Ramulu ◽  
ShilpaT Ravishanker ◽  
Chitra Chakravarthy

Author(s):  
HELDER DOMICIANO DANTAS MARTINS ◽  
HUMBERTO PEREIRA CHAVES NETO ◽  
BRUNO BEZERRA DE SOUZA ◽  
JOSE SANDRO PEREIRA DA SILVA ◽  
ADRIANO ROCHA GERMANO ◽  
...  

Author(s):  
Jeong-Seok Choi ◽  
Jae-Yol Lim ◽  
Young Chae Chu ◽  
Sun U. Song ◽  
Young-Mo Kim

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