scholarly journals Primary squamous cell carcinoma of salivary gland: Report of a rare case

2015 ◽  
Vol 11 (3) ◽  
pp. 664 ◽  
Author(s):  
AratiS Panchbhai
Rare Tumors ◽  
2020 ◽  
Vol 12 ◽  
pp. 203636132097352
Author(s):  
Silvia Mezi ◽  
Giulia Pomati ◽  
Andrea Botticelli ◽  
Francesca De Felice ◽  
Daniela Musio ◽  
...  

Primary squamous cell carcinoma of salivary gland (SCG) is an extremely rare type of malignant salivary gland tumor, which in turn results in scarcity of data available regarding both its treatment and associated genetic alterations. A retrospective analysis of 12 patients with primary SCG was conducted, along with analysis of the association between treatment, clinical/pathological characteristics, and outcomes. Most patients (8) were staged IVa, with the majority of them (10) having G3 fast growing cancer. Local and systemic recurrence were reported in only three out of nine parotid cases (0 out of 2 submandibular SCGs). In two out of eight patients local relapse occurred after integrated treatment, while recurrence occurred in two out of three patients undergoing exclusive surgery. Five patients eventually died. Treatment of resectable disease must be aggressive and multimodal, with achievement of loco-regional control in order to reduce rate of recurrence and improve outcomes. Metastatic disease would require a therapeutic strategy tailored to the molecular profile in order to improve the currently disappointing results.


2016 ◽  
Vol 111 ◽  
pp. S1104
Author(s):  
Anita Sivaraman ◽  
Rohit Anand ◽  
Amitasha Sinha ◽  
Michelle Le ◽  
Jai Parekh ◽  
...  

2020 ◽  
pp. 1-4
Author(s):  
Doris R Benavides

Introduction: Primary Squamous Cell Carcinoma of the Endometrium (PSCCE) is an extremely rare case accounting for only 0.1% of all endometrial cancer cases. It usually occurs in post-menopausal women. Case: We reported a case in the Philippines, a 64-year-old, multiparous, post-menopausal woman who presented with post-menopausal bleeding. Procedure: Endometrial curettage showed squamous cell carcinoma. She then underwent Exploratory Laparotomy, Radical Hysterectomy with Bilateral Salpingo-oophorectomy, with Bilateral Pelvic Lymph Node Dissectionand Peritoneal Fluid Cytology. Results: Histopathology of the uterus showed squamous cell carcinoma, keratinizing, with full thickness myometrial invasion. Postoperative diagnosis was primary squamous cell carcinoma, keratinizing, endometrium, stage IIIA. Patient was advised to undergo chemotherapy and radiotherapy. Conclusion: The etiology of PSCCE is still unclear and usually presents with vaginal bleeding in post-menopausal women. To diagnose, histology should meet three criteria asdefined by Fluhmann. The prognosis is poor and related to stage at diagnosis.


2014 ◽  
Vol 18 (2) ◽  
pp. 299 ◽  
Author(s):  
Vardendra Manvikar ◽  
Surekha Ramulu ◽  
ShilpaT Ravishanker ◽  
Chitra Chakravarthy

2014 ◽  
Vol 14 (1) ◽  
pp. 58 ◽  
Author(s):  
Hideyuki Wakabayashi ◽  
Takeshi Matsutani ◽  
Itsurou Fujita ◽  
Yoshikazu Kanazawa ◽  
Tsutomu Nomura ◽  
...  

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