Design, synthesis, and biological evaluation of some 1,2,3-triazole derivatives as novel amide-based inhibitors of soluble epoxide hydrolase

2021 ◽  
Author(s):  
Elham Rezaee ◽  
Hamid Reza Shadzad ◽  
Maryam Nazari ◽  
Sayyed Abbas Tabatabai
Keyword(s):  
Epoxide Hydrolase ◽  
Soluble Epoxide Hydrolase ◽  
Biological Evaluation ◽  
Design Synthesis ◽  
Triazole Derivatives ◽  
Synthesis And Biological Evaluation

Novel soluble epoxide hydrolase inhibitors with a dihydropyrimidinone scaffold: design, synthesis and biological evaluation

MedChemComm ◽  
2016 ◽  
Vol 7 (11) ◽  
pp. 2128-2135 ◽  
Author(s):  
Elham Rezaee ◽  
Mahdi Hedayati ◽  
Laleh Hoghooghi Rad ◽  
Soraya Shahhosseini ◽  
Mehrdad Faizi ◽  
...  
Keyword(s):  
Epoxide Hydrolase ◽  
Soluble Epoxide Hydrolase ◽  
Biological Evaluation ◽  
Scaffold Design ◽  
Urea Derivatives ◽  
Design Synthesis ◽  
Soluble Epoxide Hydrolase Inhibitors ◽  
Synthesis And Biological Evaluation

Amide non-urea derivatives with a dihydropyrimidinone ring as a novel secondary pharmacophore against the sEH enzyme were designed, synthesized and biologically evaluated.

Design, Synthesis, and Biological Evaluation of New Indole-Acrylamide-1,2,3-Triazole Derivatives as Potential α-Glucosidase Inhibitors

2020 ◽  
pp. 1-9
Author(s):  
Seyed Esmaeil Sadat-Ebrahimi ◽  
Hiva Babania ◽  
Maryam Mohammadi-Khanaposhtani ◽  
Mohammad Sadegh Asgari ◽  
Somayeh Mojtabavi ◽  
...  
Keyword(s):  
Biological Evaluation ◽  
Design Synthesis ◽  
Triazole Derivatives ◽  
Glucosidase Inhibitors ◽  
Synthesis And Biological Evaluation
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