Acidic fibroblast growth factor overexpression partially protects 3T3 fibroblasts from apoptosis induced by synthetic retinoid CD437

2001 ◽  
Vol 79 (2-3) ◽  
pp. 143-148 ◽  
Author(s):  
Xiaolin Wan ◽  
Petra Nass ◽  
Mark D. Duncan ◽  
John W. Harmon
Keyword(s):  
Growth Factor ◽  
Fibroblast Growth Factor ◽  
Fibroblast Growth ◽  
Acidic Fibroblast Growth Factor ◽  
3T3 Fibroblasts ◽  
Synthetic Retinoid

scholarly journals An acidic fibroblast growth factor protein generated by alternate splicing acts like an antagonist.

1992 ◽  
Vol 175 (4) ◽  
pp. 1073-1080 ◽  
Author(s):  
Y L Yu ◽  
H Kha ◽  
J A Golden ◽  
A A Migchielsen ◽  
E J Goetzl ◽  
...  
Keyword(s):  
Growth Factor ◽  
Fibroblast Growth Factor ◽  
Polymerase Chain Reaction Amplification ◽  
Sodium Dodecyl ◽  
Fibroblast Growth ◽  
Acidic Fibroblast Growth Factor ◽  
3T3 Fibroblasts ◽  
Growth Factor Gene ◽  
Cultured Human Cells ◽  
Reaction Amplification

Polymerase chain reaction amplification of cDNA for acidic fibroblast growth factor in several lines of cultured human cells revealed two forms of mRNA. The novel smaller mRNA lacks the entire second coding exon of the acidic fibroblast growth factor gene, whereas the previously identified mRNA consists of three coding exons. The truncated variant of acidic fibroblast growth factor (aFGF') is only 60 amino acids long with an apparent molecular mass of 6.7 kD on sodium dodecyl sulfate gels in contrast to 18 kD for the full-length acidic fibroblast growth factor. aFGF' elicits only minimal fibroblast proliferation and antagonizes the effects of acidic fibroblast growth factor when added exogenously to or when coexpressed with aFGF in BALB/c/3T3 fibroblasts. Thus, the truncated variant of acidic fibroblast growth factor may provide fibroblasts with a unique mechanism for endogenous regulation of their responses to acidic fibroblast growth factor.

scholarly journals Purification of Acidic Fibroblast Growth Factor from Bovine Heart and Its Localization in the Cardiac Myocytes

1989 ◽  
Vol 264 (29) ◽  
pp. 17606-17612
Author(s):  
H Sasaki ◽  
H Hoshi ◽  
Y M Hong ◽  
T Suzuki ◽  
T Kato ◽  
...  
Keyword(s):  
Growth Factor ◽  
Fibroblast Growth Factor ◽  
Cardiac Myocytes ◽  
Fibroblast Growth ◽  
Acidic Fibroblast Growth Factor ◽  
Bovine Heart

Acidic fibroblast growth factor prevents post-axotomy neuronal death of the newborn rat facial nerve

1995 ◽  
Vol 197 (3) ◽  
pp. 183-186 ◽  
Author(s):  
Pedro Cuevas ◽  
Fernando Carceller ◽  
Guillermo Giménez-Gallego
Keyword(s):  
Growth Factor ◽  
Facial Nerve ◽  
Fibroblast Growth Factor ◽  
Neuronal Death ◽  
Fibroblast Growth ◽  
Acidic Fibroblast Growth Factor ◽  
Newborn Rat

Purification of acidic fibroblast growth factor from bovine omentum

1989 ◽  
Vol 161 (1) ◽  
pp. 169-175 ◽  
Author(s):  
Tetsuya Ohtaki ◽  
Kaori Wakamatsu ◽  
Masaaki Mori ◽  
Yoshihiro Ishibashi ◽  
Tadashi Yasuhara
Keyword(s):  
Growth Factor ◽  
Fibroblast Growth Factor ◽  
Fibroblast Growth ◽  
Acidic Fibroblast Growth Factor

scholarly journals Probing the role of proline −135 on the structure, stability, and cell proliferation activity of human acidic fibroblast growth factor

2018 ◽  
Vol 654 ◽  
pp. 115-125 ◽  
Author(s):  
Julie Eberle Davis ◽  
Arwa Alghanmi ◽  
Ravi Kumar Gundampati ◽  
Srinivas Jayanthi ◽  
Ellen Fields ◽  
...  
Keyword(s):  
Cell Proliferation ◽  
Growth Factor ◽  
Fibroblast Growth Factor ◽  
Structure Stability ◽  
Fibroblast Growth ◽  
Acidic Fibroblast Growth Factor ◽  
Cell Proliferation Activity ◽  
Proliferation Activity

Development and testing of radio and enzyme immunoassays for acidic fibroblast growth factor (aFGF)

1988 ◽  
Vol 173 (2) ◽  
pp. 328-339 ◽  
Author(s):  
Daniele Caruelle ◽  
Jacques Grassi ◽  
Jose Courty ◽  
Beatrice Groux-Muscatelli ◽  
Philippe Pradelles ◽  
...  
Keyword(s):  
Growth Factor ◽  
Fibroblast Growth Factor ◽  
Fibroblast Growth ◽  
Acidic Fibroblast Growth Factor ◽  
Enzyme Immunoassays
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