Partial pressure of oxygen and partial pressure of carbon dioxide of perfluorocarbon liquid during partial liquid ventilation: their regional difference and their dependence on tidal volume and positive end-expiratory pressure level

2001 ◽  
Vol 27 (1) ◽  
pp. 36-41 ◽  
Author(s):  
Tokujiro Uchida ◽  
Kuninori Yokoyama ◽  
Koichi Nakazawa ◽  
Koshi Makita
1970 ◽  
Vol 21 (1) ◽  
pp. 77-79
Author(s):  
ASM Moosa ◽  
M Baharul Islam ◽  
Shahina Akther ◽  
M Latifur Rahman ◽  
Nazim Uddin Ahmed

Laparoscopic surgical techniques are increasingly being applied to treat cholelithiasis and other indications of gallbladder diseases. These procedures however are not without potential morbidity. Herein we describe two patients treated with laparoscopic cholecystectomy; those cases were complicated with subcutaneous emphysema and hypercarbia per-operatively. After discontinuation of pneumoperitoneum, saturation of partial pressure of oxygen (SpO2) gradually increased with improvement of the neck subcutaneous emphysema, at the same time the lung ventilation also improved. Our findings show that we have to stop pneumoperitoneum or decrease partial pressure of end carbon dioxide level immediately, when we find a sudden increase of the peak airway pressure or decrease SpO2 with subcutaneous emphysema during laparoscopic cholecystectomy.   doi: 10.3329/taj.v21i1.3225 TAJ 2008; 21(1): 77-79


1978 ◽  
Vol 77 (2) ◽  
pp. 157-160 ◽  
Author(s):  
J. R. CLAYBAUGH ◽  
J. E. HANSEN ◽  
D. B. WOZNIAK

SUMMARY Eight men, 19-35 years of age, breathed 20·9% (normal oxygen), 13·9% (mild hypoxia) or 11·1% (severe hypoxia) oxygen in nitrogen gas mixtures during three 20 min periods, which were separated by 1 h recovery periods. The order in which the gas mixtures were breathed was random. The partial pressure of oxygen decreased from a mean of 93·5 during exposure to normal oxygen to 53·9 and 36·7 mmHg during mild and severe hypoxia respectively. There were corresponding decreases in haemoglobin saturation. The partial pressure of carbon dioxide was lower and the pH higher during severe hypoxia than during exposure to normal oxygen. There were no changes in the plasma osmolality or in the concentrations of sodium or potassium in the plasma. There was a tendency for both the renin activity and the concentration of aldosterone in the plasma to decrease progressively as the percentage of oxygen breathed decreased. Unlike severe hypoxia, mild hypoxia suppressed the concentration of antidiuretic hormone (ADH) in the plasma of all subjects by about 59%; during severe hypoxia the reduction was not significant, being only about 33%. These data are consistent with the suggestion that the effect of hypoxia on the release of ADH is dependent on the level of hypoxia.


Author(s):  
J.A. Johannigman ◽  
K. Davis ◽  
R.S. Campbell ◽  
F.A. Luchette ◽  
J.M. Hurst ◽  
...  

1996 ◽  
Vol 84 (4) ◽  
pp. 882-889. ◽  
Author(s):  
Agneta M. Markstrom ◽  
Michael Lichtwarck-Aschoff ◽  
Bjorn A. Svensson ◽  
K. Anders Nordgren ◽  
Ulf H. Sjostrand

Background Recognition of the potential for ventilator-associated lung injury has renewed the debate on the importance of the inspiratory flow pattern. The aim of this study was to determine whether a ventilatory pattern with decelerating inspiratory flow, with the major part of the tidal volume delivered early, would increase functional residual capacity at unchanged (or even reduced) inspiratory airway pressures and improve gas exchange at different positive end-expiratory pressure levels. Methods Surfactant depletion was induced by repeated bronchoalveolar lavage in 13 anesthetized piglets. Decelerating and constant inspiratory flow ventilation was applied at positive end-expiratory pressure levels of 22, 17, 13, 9, and 4 cm H(2)O. Tidal volume, inspiration-to-expiration ratio, and ventilatory frequency were kept constant. Airway pressures, gas exchange, functional residual capacity (using a wash-in/washout method with sulfurhexafluoride), central hemodynamics, and extravascular lung water (using the thermo-dye-indicator dilution technique) were measured. Results Decelerating inspiratory flow yielded a lower arterial carbon dioxide tension compared to constant flow, that is, it improved alveolar ventilation. There were no differences between the flow patterns regarding end-inspiratory occlusion airway pressure, end-inspiratory lung volume, static compliance, or arterial oxygen tension. No differences were seen in hemodynamics and oxygen delivery. Conclusions The decelerating inspiratory flow pattern increased carbon dioxide elimination, without any reduction of inspiratory airway pressure or apparent improvement in arterial oxygen tension. It remains to be established whether these differences are sufficiently pronounced to justify therapeutic consideration.


2001 ◽  
Vol 47 (1) ◽  
pp. 82-89 ◽  
Author(s):  
Simone Laukemper-Ostendorf ◽  
Alexander Scholz ◽  
Katja Bürger ◽  
Claus P. Heussel ◽  
Marc Schmittner ◽  
...  

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