Vaginal prolapse repair with or without a midurethral sling in women with genital prolapse and occult stress urinary incontinence: a randomized trial

2016 ◽  
Vol 27 (7) ◽  
pp. 1029-1038 ◽  
Author(s):  
J. Marinus van der Ploeg ◽  
◽  
Katrien Oude Rengerink ◽  
Annemarie van der Steen ◽  
Jules H. Schagen van Leeuwen ◽  
...  
Author(s):  
Giulia I. Lane ◽  
Colby A. Dixon ◽  
M. Louis Moy ◽  
Cynthia S. Fok

This chapter summarizes the results of the Outcomes Following Vaginal Prolapse Repair and Midurethral Sling (OPUS) trial, in which women without stress urinary incontinence undergoing prolapse surgery were randomized to a midurethral sling or no concomitant midurethral sling. The OPUS trial found that women randomized to undergo prophylactic concomitant midurethral sling at the time of transvaginal repair for pelvic organ prolapse had lower rates of urinary incontinence at 3 and 12 months but also experienced higher rates of adverse events such as bladder perforation, major bleeding, and urinary tract infections.


Author(s):  
Deepali Maheshwari ◽  
Ellen Solomon

The OPUS (Outcomes Following Vaginal Prolapse Repair and Midurethral Sling) trial examined the effect of a prophylactic midurethral sling at the time of vaginal prolapse surgery in women without stress urinary incontinence. Women undergoing surgery for pelvic organ prolapse are at risk for developing postoperative stress urinary incontinence even if they do not complain of it preoperatively. This was a randomized controlled trial with intervention patients in the prophylactic midurethral sling group and control patients in the sham group. The authors identified a lower rate of de novo urinary incontinence at 3 and 12 months in women who received a prophylactic midurethral sling at the time of vaginal prolapse surgery. However, they also found higher rates of adverse events. This study provides valuable information for patient counseling and surgical decision-making with respect to concurrent prolapse and incontinence surgeries.


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