Feedforward postural muscle modes and multi-mode coordination in mild cerebellar ataxia

2011 ◽  
Vol 210 (1) ◽  
pp. 153-163 ◽  
Author(s):  
Tadayoshi Asaka ◽  
Yun Wang
Keyword(s):  
Cerebellar Ataxia ◽  
Postural Muscle ◽  
Multi Mode ◽  
Muscle Modes

scholarly journals Learning effects on muscle modes and multi-mode postural synergies

2007 ◽  
Vol 184 (3) ◽  
pp. 323-338 ◽  
Author(s):  
Tadayoshi Asaka ◽  
Yun Wang ◽  
Junko Fukushima ◽  
Mark L. Latash
Keyword(s):  
Learning Effects ◽  
Multi Mode ◽  
Postural Synergies ◽  
Muscle Modes

scholarly journals Effects of Aging on Feedforward Postural Synergies

2008 ◽  
Vol 20 (1) ◽  
pp. 63-70 ◽  
Author(s):  
Tadayoshi Asaka ◽  
Yun Wang
Keyword(s):  
Time Lag ◽  
Principal Component ◽  
Young Group ◽  
Co Activation ◽  
Extensor Muscles ◽  
Postural Muscle ◽  
Older Subjects ◽  
Effects Of Aging ◽  
Postural Synergies ◽  
Muscle Modes

Effects of Aging on Feedforward Postural SynergiesWe investigated the effects of aging on postural muscles covariate patterns prior to voluntary perturbations. Nine healthy young and nine older subjects were instructed to release a load in a self-paced manner. The results of cross-correlation analyses showed that the average time lag corresponding peak correlation coefficient between trunk flexor and extensor muscles in the older group was significantly shorter, compared to that in the young group. The results of principal component analysis showed that the co-contraction Muscle-modes in the older group were observed more frequently than those in the young group. These results indicate that the older group showed changes in the anticipatory postural muscle co-variation, suggesting the transition from reciprocal to co-activation pattern with aging.

Multi-mode light microscopy of microtubule assembly dynamics and chromosome movement in vivo and In vitro

1996 ◽  
Vol 54 ◽  
pp. 730-731
Author(s):  
E. D. Salmon ◽  
J. C. Waters ◽  
C. Waterman-Storer
Keyword(s):  
Imaging System ◽  
Ccd Camera ◽  
Transmitted Light ◽  
Microtubule Assembly ◽  
Live Cells ◽  
Optical Efficiency ◽  
Multiple Band ◽  
Multi Mode

We have developed a multi-mode digital imaging system which acquires images with a cooled CCD camera (Figure 1). A multiple band pass dichromatic mirror and robotically controlled filter wheels provide wavelength selection for epi-fluorescence. Shutters select illumination either by epi-fluorescence or by transmitted light for phase contrast or DIC. Many of our experiments involve investigations of spindle assembly dynamics and chromosome movements in live cells or unfixed reconstituted preparations in vitro in which photodamage and phototoxicity are major concerns. As a consequence, a major factor in the design was optical efficiency: achieving the highest image quality with the least number of illumination photons. This principle applies to both epi-fluorescence and transmitted light imaging modes. In living cells and extracts, microtubules are visualized using X-rhodamine labeled tubulin. Photoactivation of C2CF-fluorescein labeled tubulin is used to locally mark microtubules in studies of microtubule dynamics and translocation. Chromosomes are labeled with DAPI or Hoechst DNA intercalating dyes.

Homozygous Splice Mutation in CWF19L1 in Two Brothers with Autosomal Recessive Cerebellar Ataxia

2017 ◽  
Vol 48 (S 01) ◽  
pp. S1-S45
Author(s):  
A. Enderli ◽  
B. Heinrich ◽  
P. Joset ◽  
J. De Geyter ◽  
J. Scheer ◽  
...  
Keyword(s):  
Cerebellar Ataxia ◽  
Autosomal Recessive ◽  
Splice Mutation ◽  
Autosomal Recessive Cerebellar Ataxia

Time-Frequency Channel Parameterization with Application to Multi-Mode Receivers

2009 ◽  
Vol E92-B (12) ◽  
pp. 3717-3725
Author(s):  
Thomas HUNZIKER ◽  
Ziyang JU ◽  
Dirk DAHLHAUS
Keyword(s):  
Frequency Channel ◽  
Time Frequency ◽  
Multi Mode

Split pump region in 1.55 ^|^mu;m InGaAsP/InGaAsP asymmetric active multi-mode interferometer laser diode for improved modulation bandwidth

2014 ◽  
Vol E97.C (7) ◽  
pp. 781-786 ◽  
Author(s):  
Mohammad NASIR UDDIN ◽  
Takaaki KIZU ◽  
Yasuhiro HINOKUMA ◽  
Kazuhiro TANABE ◽  
Akio TAJIMA ◽  
...  
Keyword(s):  
Laser Diode ◽  
Modulation Bandwidth ◽  
Multi Mode

CANVAS is a common form of late-onset hereditary ataxia

2020 ◽  
pp. 51-52
Author(s):  
Е.П. Нужный ◽  
Н.Ю. Абрамычева ◽  
Е.Г. Воробьева ◽  
Е.О. Иванова ◽  
Ю.А. Шпилюкова ◽  
...  
Keyword(s):  
Cerebellar Ataxia ◽  
Clinical Picture ◽  
Autosomal Recessive ◽  
Late Onset ◽  
Repeat Expansion ◽  
Hereditary Ataxia ◽  
Recessive Ataxia ◽  
Autosomal Recessive Ataxia

Синдром CANVAS (мозжечковая атаксия, невропатия и вестибулярная арефлексия) - аутосомно-рецессивная атаксия с поздним дебютом, обусловленная носительством биаллельной экспансии (AAGGG)n во 2-м интроне гена RFC1. До настоящего момента отсутствуют сведения о распространенности данного заболевания в российских семьях. Нами был проведен поиск биаллельной экспансии AAGGG-повторов у 35 российских пациентов с поздней мозжечковой атаксией. Верифицированы 5 пациентов (14,3%) с синдромом CANVAS и характерной клинической картиной. CANVAS (cerebellar ataxia, neuropathy and vestibular areflexia) is a late-onset autosomal recessive ataxia due to biallelic (AAGGG)n repeat expansion in the 2nd intron of the RFC1 gene. There is no information on the CANVAS prevalence in Russian families. We searched for biallelic expansion of AAGGG repeats in 35 Russian patients with late-onset cerebellar ataxia. Five patients (14.3%) with CANVAS syndrome and a characteristic clinical picture were verified.

Sign in / Sign up

Export Citation Format

Share Document