Effect of Alendronate on Periprosthetic Bone Loss After Total Knee Arthroplasty: A One-Year, Randomized, Controlled Trial of 19 Patients

2002 ◽  
Vol 71 (6) ◽  
pp. 472-477 ◽  
Author(s):  
T.A. Soininvaara ◽  
J.S. Jurvelin ◽  
H.J.A. Miettinen ◽  
O.T. Suomalainen ◽  
E.M. Alhava ◽  
...  
2021 ◽  
Vol 103-B (10) ◽  
pp. 1561-1570
Author(s):  
Mark J. G. Blyth ◽  
Matthew S. Banger ◽  
James Doonan ◽  
Bryn G. Jones ◽  
Angus D. MacLean ◽  
...  

Aims The aim of this study was to compare the clinical outcomes of robotic arm-assisted bi-unicompartmental knee arthroplasty (bi-UKA) with conventional mechanically aligned total knee arthroplasty (TKA) during the first six weeks and at one year postoperatively. Methods A per protocol analysis of 76 patients, 43 of whom underwent TKA and 34 of whom underwent bi-UKA, was performed from a prospective, single-centre, randomized controlled trial. Diaries kept by the patients recorded pain, function, and the use of analgesics daily throughout the first week and weekly between the second and sixth weeks. Patient-reported outcome measures (PROMs) were compared preoperatively, and at three months and one year postoperatively. Data were also compared longitudinally and a subgroup analysis was conducted, stratified by preoperative PROM status. Results Both operations were shown to offer comparable outcomes, with no significant differences between the groups across all timepoints and outcome measures. Both groups also had similarly low rates of complications. Subgroup analysis for preoperative psychological state, activity levels, and BMI showed no difference in outcomes between the two groups. Conclusion Robotic arm-assisted, cruciate-sparing bi-UKA offered similar early clinical outcomes and rates of complications to a mechanically aligned TKA, both in the immediate postoperative period and up to one year following surgery. Further work is required to identify which patients with osteoarthritis of the knee will derive benefit from a cruciate-sparing bi-UKA. Cite this article: Bone Joint J 2021;103-B(10):1561–1570.


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