Reversed vascular pattern of descending branch of the lateral circumflex femoral vessel: an unreported entity

AbstractLongitudinal and perpendicular changes in the blood vessels of the vocal fold have been related to the advancement from benign to malignant laryngeal cancer stages. The combination of Contact Endoscopy (CE) and Narrow Band Imaging (NBI) provides intraoperative realtime visualization of vascular pattern in Larynx. The evaluation of these vascular patterns in CE+NBI images is a subjective process leading to differentiation difficulty and subjectivity between benign and malignant lesions. The main objective of this work is to compare multi-observer classification versus automatic classification of laryngeal lesions. Six clinicians visually classified CE+NBI images into benign and malignant lesions. For the automatic classification of CE+NBI images, we used an algorithm based on characterizing the level of the vessel’s disorder. The results of the manual classification showed that there is no objective interpretation, leading to difficulties to visually distinguish between benign and malignant lesions. The results of the automatic classification of CE+NBI images on the other hand showed the capability of the algorithm to solve these issues. Based on the observed results we believe that, the automatic approach could be a valuable tool to assist clinicians to classifying laryngeal lesions.

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VASCULAR PATTERN AND RADIOLOGICAL FOLLOW UP IN A CASE OF PONTINE WARNING SYNDROME

Heliyon ◽

10.1016/j.heliyon.2021.e07369 ◽

2021 ◽

pp. e07369

Author(s):

Carmelo Tiberio Currò ◽

Isabella Francalanza ◽

Masina Cotroneo ◽

Cristina Dell’Aera ◽

Carmela Casella ◽

...

Keyword(s):

Vascular Pattern

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Metastatic small cell carcinoma of the lung with prominent spindle cell morphology and hemangiopericytoma-like vascular pattern: A sarcoma mimicker

SAGE Open Medical Case Reports ◽

10.1177/2050313x20981177 ◽

2020 ◽

Vol 8 ◽

pp. 2050313X2098117

Author(s):

Esra Nsour ◽

Ali Al Khader ◽

Bushra Al-Tarawneh

Keyword(s):

Cell Carcinoma ◽

Small Cell Carcinoma ◽

Spindle Cell ◽

Small Cell ◽

Nerve Sheath Tumor ◽

Vascular Pattern ◽

Nerve Sheath ◽

History Of ◽

Wall Mass ◽

Aggressive Clinical Behavior

Small cell carcinoma is a malignant neuroendocrine tumor with aggressive clinical behavior. Histologically, the tumor is characterized by the proliferation of small, round, blue cells. Here, we present the case of a 50-year-old man with a 1-month history of enlarging chest wall mass. Microscopic examination of the lesion revealed a highly cellular neoplasm composed of closely packed, atypical spindle cells with scant cytoplasm, inconspicuous nucleoli, and brisk mitotic activity. The hemangiopericytoma-like vascular pattern was prominent. Areas showing a fibrosarcoma-like fascicular pattern were also observed. The tumor was immunohistochemically positive for TTF1, synaptophysin, and chromogranin, confirming small cell carcinoma. Further investigations revealed a lung origin and widespread metastases. The tumor in this case closely mimicked synovial sarcoma or malignant peripheral nerve sheath tumor. Small cell carcinoma demonstrates a hemangiopericytoma-like pattern that can mimic sarcoma histologically. This is a serious pitfall that can significantly affect the speed of diagnosis and management.

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