VASCULAR PATTERN AND RADIOLOGICAL FOLLOW UP IN A CASE OF PONTINE WARNING SYNDROME

AbstractWe report a case of uncomplicated giant fetal hepatic hemangioma with a good outcome. A 57×38 mm heterogeneous hepatic mass, mostly hypoechogenic was observed post prenatal ultrasound, at 33 weeks’ gestation (WG) and 5 days. Color Doppler confirmed the vascular pattern of the mass. The image size stayed stable, with no associated complications, and a cesarean birth at 37 WG was performed for fetal protection. Subsequent postnatal follow-up showed spontaneous regression of the tumor. Antenatal diagnosis and management of fetal liver masses are discussed in this paper. This case supports the hypothesis that complications of giant fetal hepatic hemangioma are not related only to its size. Prognostic factors and guidelines for follow-up need to be determined.

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Proposal for management and dermoscopy follow-up of nevi in patients affected by oculocutaneous albinism type Ia

Dermatology Practical & Conceptual ◽

10.5826/dpc.0701a07 ◽

2017 ◽

Author(s):

Rosario Peralta ◽

Emilia Cohen Sabban ◽

Paula Friedman ◽

Carolina Marcucci ◽

Luis A. Bollea Garlatti ◽

...

Keyword(s):

Confocal Microscopy ◽

Great Risk ◽

Oculocutaneous Albinism ◽

Amelanotic Melanoma ◽

Reflectance Confocal Microscopy ◽

Comparative Approach ◽

Vascular Pattern ◽

Type Ia ◽

Difficult Cases

Albino patients are at great risk for developing cutaneous neoplasms, including melanomas. In this paper we describe the dermatoscopic findings of nevi in two patients with oculocutaneous albinism type Ia (OCA-Ia) highlighting that they manifest a vascular pattern similar to that described for amelanotic melanoma. We propose managing these patients with dermoscopy, using the comparative approach, digital follow up (DFU), and reflectance confocal microscopy as a complementary tool for difficult cases.

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AN OBSERVATIONAL STUDY OF DERMOSCOPIC FINDINGS IN CASES OF LICHEN PLANUS IN INDIAN SKIN

10.36106/ijsr/7007594 ◽

2020 ◽

pp. 1-2

Author(s):

Mayuri Ranpariya ◽

Brijesh Parmar

Keyword(s):

Observational Study ◽

Lichen Planus ◽

Tertiary Care ◽

Invasive Procedure ◽

Vascular Pattern ◽

Background Color ◽

Non Invasive ◽

Care Institute ◽

Almost All

INTRODUCTION: Dermoscopy is non-invasive procedure used for diagnosis of various dermatoses. As there are very few dermoscopic studies available on LP in India, this study was undertaken to explore its role. AIM: To study dermoscopic features in LP cases. METHOD: Dermoscopic examination was done in 65 cases of LP over the study period of 3 months at a tertiary care institute. RESULTS: Total 155 lesions of 29 classical LP(CLP), 13 hypertrophic LP(HLP), 9 eruptive LP(ELP), 6 lichen planus pigmentosus(LPP), 4 lichen plano pilaris(LPPI), 2 linear LP(LLP), 2 follicular LP(FLP) cases were examined. Lesions of CLP, ELP and LLP were examined in which: Active lesions (94 lesions) - Wickham’s striae (WS): commonest pattern was radial streaming (40% lesions) and Color was white (91.48% lesions). Pigment pattern (PP): absent in almost all lesions. Commonest vascular pattern (VP): radial linear in 68.08% lesions. Commonest background Color (BC): violet Regressed lesions (20 lesions) - WS: absent in 95% lesions. Commonest PP: diffuse dots/globules (80% lesions). VP: absent. BC: brown (100% lesions) HLP (26 lesions)-Keratin Plugs (KP) in 84.61% lesions, VP: absent. FLP (2 lesions) -follicular KP in all lesions. LPP (9 lesions)-Reticular & granular Pattern was seen in all lesions, commonest pigment was dark brown, different intensity of pigmentation was present in 4 lesions. LPPI (4 lesions)-Follicular atrophy, peripilar cast and interfollicular reticular brownish pigmentation was seen in all lesions. CONCLUSION: Dermoscopic findings of LP and its variants can be useful for diagnosis and follow up.

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Evaluation of narrow band imaging in the assessment of laryngeal granuloma

Scientific Reports ◽

10.1038/s41598-019-50699-8 ◽

2019 ◽

Vol 9 (1) ◽

Cited By ~ 1

Author(s):

H. Klimza ◽

W. Pietruszewska ◽

J. Jackowska ◽

K. Piersiala ◽

M. Wierzbicka

Keyword(s):

Tumor Recurrence ◽

Severe Dysplasia ◽

Vascular Pattern ◽

Local Tumor ◽

Local Tumor Recurrence ◽

Final Histology ◽

Group A ◽

Laryngeal Granuloma ◽

Benign Laryngeal Lesions

Abstract Laryngeal granulomas belong to common complications following trans-oral laser microsurgery (TLM). The aim of this study was to evaluate NBI in the differentiation between granuloma-like lesions and local tumor recurrence. 154 consecutive patients after TLM due to early laryngeal cancer were enrolled. In the group, a monthly follow-up including NBI endoscopy was performed. Moderate and severe dysplasia, carcinoma in situ and invasive cancer were defined as positive histology, laryngeal granuloma and other benign laryngeal lesions as negative histology and premalignant lesions as suspicious histology. In 47/154 (31%) cases, granuloma-like lesion (GLL) was found. Patients with GLL were divided into two groups based on the NBI classification. In all patients, the microvascular pattern in NBI was compared with the final histology. In group A, with suspicious, perpendicular vessels, 13/13 (100%) samples were positive. In group B, with normal vascular pattern 3/34 (9%) samples were positive and 31/34 (91%) samples were negative. There was a significant correlation between the positive NBI vascular pattern and the final histology (p = 0.00001). Sensitivity, specificity, accuracy of NBI were as follows: 81%, 100%, 94%, respectively.Based on our results, NBI can reliably differentiate between postoperative laryngeal granuloma and local tumor recurrence. In such a manner, this method is very helpful in the follow-up of tumor patients.

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P218 Linked colour imaging predicts the risk of the clinical relapse in ulcerative colitis

Journal of Crohn s and Colitis ◽

10.1093/ecco-jcc/jjz203.347 ◽

2020 ◽

Vol 14 (Supplement_1) ◽

pp. S250-S250

Author(s):

S Kanmura ◽

Y Komaki ◽

F Komaki ◽

A Tanaka ◽

F Sasaki ◽

...

Keyword(s):

Ulcerative Colitis ◽

Relapse Rate ◽

Univariate Analysis ◽

Additional Treatment ◽

Chronic Inflammatory Bowel Disease ◽

Clinical Relapse ◽

Vascular Pattern ◽

Endoscopic Observation ◽

Significant Difference

Abstract Background Ulcerative colitis (UC) is a chronic inflammatory bowel disease with unknown aetiology. Recently, mucosal healing (MH) has emerged as an important therapeutic endpoint in UC. Linked colour imaging (LCI) is a novel endoscopic system that enhances the colour differences of the gastrointestinal mucosa. We aimed to evaluate the correlation between the endoscopic observation using LCI and the clinical relapse rate in UC patients. Methods We retrospectively analysed UC patients who underwent a total colonoscopy between August 2016 and May 2019 at our facility with Mayo endoscopic score (MES) of 0 or 1. We assessed the most relevant endoscopic findings, including erythema, vascular pattern, and friability using white-light imaging (WLI) and LCI observation. We analysed the correlation of clinical relapse rate, which means requiring additional treatment for UC, during the 2-year follow-up period with endoscopic assessment using WLI and LCI. We also evaluated the utility of LCI-observation method for predicting the prognosis in UC patients with clinical remission. Results Forty-seven patients were analysed, and clinical relapse was observed in 10 patients (21%) during the 2-year. Univariate analysis revealed a significant difference in decreased vascular pattern and friability between the clinical relapse and remission groups; multivariate analysis showed decreased vascular pattern observed on LCI as the only variable, which remained significantly associated with clinical relapse (p <0.03). We defined LCI-mucosal score (MS) as LCI-MS 0, distinct vascular pattern and no friability; LCI-MS 1, either indistinct purple/magenta vascular pattern or friability; and LCI-MS 2, both indistinct purple/magenta vascular pattern or friability on LCI observation. The relapse rate in patients with LCI-MS 0 was 10% (3/30), which was significantly lower than in patients with LCI-MS 1 or 2 (36 %; 6/16). Conclusion LCI findings have the diagnostic implications in predicting the risk of clinical relapse in UC during the 2-year follow-up period.

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Therapy and prevention for mental health: What if mental diseases are mostly not brain disorders?

Behavioral and Brain Sciences ◽

10.1017/s0140525x1800105x ◽

2019 ◽

Vol 42 ◽

Cited By ~ 2

Author(s):

John P. A. Ioannidis

Keyword(s):

Mental Health ◽

Mental Disease ◽

Brain Disorders ◽

Social Stressors ◽

Labor Education ◽

Mental Diseases ◽

Long Term Follow Up ◽

Political Decisions

AbstractNeurobiology-based interventions for mental diseases and searches for useful biomarkers of treatment response have largely failed. Clinical trials should assess interventions related to environmental and social stressors, with long-term follow-up; social rather than biological endpoints; personalized outcomes; and suitable cluster, adaptive, and n-of-1 designs. Labor, education, financial, and other social/political decisions should be evaluated for their impacts on mental disease.

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Brief summary of Kleť photographic search programme for minor planets

International Astronomical Union Colloquium ◽

10.1017/s0252921100031419 ◽

1999 ◽

Vol 173 ◽

pp. 189-192

Author(s):

J. Tichá ◽

M. Tichý ◽

Z. Moravec

Keyword(s):

Ccd Camera ◽

Minor Planet ◽

Minor Planets ◽

Main Belt

AbstractA long-term photographic search programme for minor planets was begun at the Kleť Observatory at the end of seventies using a 0.63-m Maksutov telescope, but with insufficient respect for long-arc follow-up astrometry. More than two thousand provisional designations were given to new Kleť discoveries. Since 1993 targeted follow-up astrometry of Kleť candidates has been performed with a 0.57-m reflector equipped with a CCD camera, and reliable orbits for many previous Kleť discoveries have been determined. The photographic programme results in more than 350 numbered minor planets credited to Kleť, one of the world's most prolific discovery sites. Nearly 50 per cent of them were numbered as a consequence of CCD follow-up observations since 1994.This brief summary describes the results of this Kleť photographic minor planet survey between 1977 and 1996. The majority of the Kleť photographic discoveries are main belt asteroids, but two Amor type asteroids and one Trojan have been found.

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Intranuclear Crystals in Regenerating Canine Kidneys

Proceedings, annual meeting, Electron Microscopy Society of America ◽

10.1017/s0424820100072502 ◽

1973 ◽

Vol 31 ◽

pp. 412-413

Author(s):

D.G. Osborne ◽

L.J. McCormack ◽

M.O. Magnusson ◽

W.S. Kiser

Keyword(s):

Epithelial Cell ◽

Epithelial Cells ◽

Tubular Epithelial Cell ◽

Tubular Epithelial Cells ◽

Cell Nuclei ◽

Crystalline Structures ◽

Small Crystals ◽

Membrane Bound

During a project in which regenerative changes were studied in autotransplanted canine kidneys, intranuclear crystals were seen in a small number of tubular epithelial cells. These crystalline structures were seen in the control specimens and also in regenerating specimens; the main differences being in size and number of them. The control specimens showed a few tubular epithelial cell nuclei almost completely occupied by large crystals that were not membrane bound. Subsequent follow-up biopsies of the same kidneys contained similar intranuclear crystals but of a much smaller size. Some of these nuclei contained several small crystals. The small crystals occurred at one week following transplantation and were seen even four weeks following transplantation. As time passed, the small crystals appeared to fuse to form larger crystals.

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Electron Microscopy of Human Gallstones

Proceedings, annual meeting, Electron Microscopy Society of America ◽

10.1017/s0424820100065523 ◽

1971 ◽

Vol 29 ◽

pp. 296-297

Author(s):

C. Wolpers ◽

R. Blaschke

Keyword(s):

Electron Microscopy ◽

Room Temperature ◽

Bile Pigment ◽

X Ray Diffraction ◽

Triclinic Crystal System ◽

X Ray ◽

Follow Up Study ◽

Infra Red ◽

Main Components

Scanning microscopy was used to study the surface of human gallstones and the surface of fractures. The specimens were obtained by operation, washed with water, dried at room temperature and shadowcasted with carbon and aluminum. Most of the specimens belong to patients from a series of X-ray follow-up study, examined during the last twenty years. So it was possible to evaluate approximately the age of these gallstones and to get information on the intensity of growing and solving.Cholesterol, a group of bile pigment substances and different salts of calcium, are the main components of human gallstones. By X-ray diffraction technique, infra-red spectroscopy and by chemical analysis it was demonstrated that all three components can be found in any gallstone. In the presence of water cholesterol crystallizes in pane-like plates of the triclinic crystal system.

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Articulatory Intervention for the Visually Impaired

Language Speech and Hearing Services in Schools ◽

10.1044/0161-1461.1003.139 ◽

1979 ◽

Vol 10 (3) ◽

pp. 139-144

Author(s):

Cheri L. Florance ◽

Judith O’Keefe

Keyword(s):

High School ◽

High School Students ◽

Behavior Change ◽

Visually Impaired ◽

School Students ◽

Handicapped Children ◽

Paired Stimuli ◽

Visually Handicapped ◽

Parent Program

A modification of the Paired-Stimuli Parent Program (Florance, 1977) was adapted for the treatment of articulatory errors of visually handicapped children. Blind high school students served as clinical aides. A discussion of treatment methodology, and the results of administrating the program to 32 children, including a two-year follow-up evaluation to measure permanence of behavior change, is presented.

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