The differentiation between aneurysmal bone cyst and telangiectatic osteosarcoma: a clinical, radiographic and MRI study

Aneurysmal bone cyst (ABC) and telangiectatic osteosarcoma (TOS) share a lot of similarities in terms of the initial clinical presentation, the radiological semiotics and even the morphological pattern, however, they are completely different nosological entities requiring absolutely different treatment approaches. This article reports a clinical case of TOS of the femur which developed 1.5 years after the treatment of ABC of the same location and presents an analysis of literature on the differential diagnosis of these diseases, the modern concept of the pathogenesis of ABC and the possibility of the transformation of ABC into TOS. The patient's parents gave consent to the use of their child's data, including photographs, for research purposes and in publications.

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Aggressive aneurysmal bone cyst of the maxilla confused with telangiectatic osteosarcoma

Auris Nasus Larynx ◽

10.1016/j.anl.2011.05.002 ◽

2012 ◽

Vol 39 (3) ◽

pp. 337-340 ◽

Cited By ~ 9

Author(s):

Hyun-Min Lee ◽

Kyu-Sup Cho ◽

Kyung-Un Choi ◽

Hwan-Jung Roh

Keyword(s):

Aneurysmal Bone Cyst ◽

Bone Cyst ◽

Telangiectatic Osteosarcoma

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Five-year evolution of a telangiectatic osteosarcoma initially managed as an aneurysmal bone cyst

Skeletal Radiology ◽

10.1007/s00256-004-0865-8 ◽

2004 ◽

Vol 34 (5) ◽

pp. 290-294 ◽

Cited By ~ 24

Author(s):

Tsuyoshi Saito ◽

Yoshinao Oda ◽

Ken-ichi Kawaguchi ◽

Kazuhiro Tanaka ◽

Shuichi Matsuda ◽

...

Keyword(s):

Aneurysmal Bone Cyst ◽

Bone Cyst ◽

Telangiectatic Osteosarcoma

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Primary telangiectatic osteosarcoma of the cervical spine

Journal of Neurosurgery Spine ◽

10.3171/2011.12.spine111037 ◽

2012 ◽

Vol 16 (4) ◽

pp. 373-378 ◽

Cited By ~ 4

Author(s):

Mazda K. Turel ◽

Vivek Joseph ◽

Vandita Singh ◽

Vinu Moses ◽

Vedantam Rajshekhar

Keyword(s):

Cervical Spine ◽

Aneurysmal Bone Cyst ◽

Histopathological Examination ◽

Bone Cyst ◽

Biological Behavior ◽

Adjuvant Radiation ◽

Diagnostic Challenge ◽

Telangiectatic Osteosarcoma ◽

History Of ◽

Glue Embolization

Telangiectatic osteosarcoma (TOS) is one of the 8 subtypes of osteosarcoma that infrequently affects the spine. The radiopathological features of TOS overlap with those of more benign entities, most commonly the aneurysmal bone cyst), and therefore is a significant diagnostic challenge. It is a rare but well-described entity in the thoracolumbar and sacral spine, and to the authors' knowledge has not been previously reported in the cervical spine. The authors report the case of a 15-year-old boy who presented with a 6-month history of neck pain and torticollis. He underwent preoperative glue embolization followed by a staged subtotal C-5 spondylectomy and posterior fusion for a C-5 vertebral body lytic expansile lesion. Histopathological examination showed the lesion to be TOS. The surgery was followed by adjuvant radiation and chemotherapy with a favorable outcome at the 1-year follow-up. This report reiterates that TOS is an important differential diagnosis for aneurysmal bone cyst and giant-cell tumor of the spine, as its biological behavior and clinical outcome differ from those of these more benign lesions, which it mimics.

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