scholarly journals Can 68GA-PSMA or radiolabeled choline PET/CT guide salvage lymph node dissection in recurrent prostate cancer?

2016 ◽  
Vol 43 (8) ◽  
pp. 1407-1409 ◽  
Author(s):  
Fabio Zattoni ◽  
Andrea Guttilla ◽  
Laura Evangelista
Keyword(s):  
Prostate Cancer ◽  
Lymph Node ◽  
Lymph Node Dissection ◽  
Recurrent Prostate Cancer ◽  
Node Dissection ◽  
Choline Pet ◽  
Pet Ct ◽  
Salvage Lymph Node Dissection

[11C]Choline PET/CT for Targeted Salvage Lymph Node Dissection in Patients with Biochemical Recurrence after Primary Curative Therapy for Prostate Cancer

2008 ◽  
Vol 81 (2) ◽  
pp. 191-197 ◽  
Author(s):  
Ludwig Rinnab ◽  
Felix M. Mottaghy ◽  
Joerg Simon ◽  
Bjoern G. Volkmer ◽  
Robert de Petriconi ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Lymph Node ◽  
Lymph Node Dissection ◽  
Biochemical Recurrence ◽  
Node Dissection ◽  
Curative Therapy ◽  
Choline Pet ◽  
Pet Ct ◽  
Salvage Lymph Node Dissection

Is there an additional benefit of Tc-99m-PSMA-guided gamma probe use for salvage lymph node dissection in recurrent prostate cancer.

2017 ◽  
Vol 35 (6_suppl) ◽  
pp. e591-e591 ◽  
Author(s):  
David Pfister ◽  
Matthias Schmidt ◽  
Friederike Haidl ◽  
Daniel Porres-Knoblauch ◽  
Alexander Drzezga ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Lymph Node ◽  
Lymph Nodes ◽  
Lymph Node Dissection ◽  
Gamma Probe ◽  
Recurrent Prostate Cancer ◽  
Node Dissection ◽  
Psma Pet ◽  
Pet Ct ◽  
Salvage Lymph Node Dissection

e591 Background: PSMA-PET/CT is the most sensitive diagnostic tool in biochemical recurrent prostate cancer to detect minimal metastatic disease. However, it may be difficult to localize small PSMA-positive lymph nodes intraoperatively. Therefore, it was the aim to investigate whether preoperative Tc-99m-PSMA targeting may improve intraoperative tumor localization by use of a gamma probe. Methods: In 13 Patients Ga-68-PSMA-PET/CT identified iliac lymph nodes in patients suitable for salvage lymph node dissection. On the day before operation a mean activity of 480 MBq Tc-99m-PSMA was injected and gamma camera scintigraphy + SPECT was performed 4-5 hours after tracer application. About 24 hours after tracer application a salvage lymph node dissection was performed on the side of initial suspicious lymph node metastases. Sensitivity, specifity, pos and neg. predictive values were calulated for PSMA-PET/CT and gamma probe use to analyse the additional use. Results: In 9 / 13 patients PSMA-positive metastatic lymph nodes were identified in Ga-68 PSMA-PET/CT. A total of 156 lymph nodes were removed with 14 lymph nodes in 9 patients being positive in histopathologic examination. Sensitivity, specifity, pos and neg. predictive values for PSMA PET/CT and gamma probe were 85% and 79%, 99% and 100%, 85% and 100% and 99% and 98% respectively. In one patient only gamma probe use identified a pathologic lymph node. Conclusions: Gamma probe guided salvage lymph node dissection in PSA recurrent prostate cancer is feasible and had a high concordance with PSMA-PET/CT. However, the additional diagnostic benefit is limited compared to PSMA-PET/CT because in only one patient (7%) a positive lymph node could be identified with the use of the gamma probe outside the standard operative area in salvage lymph node dissection.

Robotic salvage lymph node dissection in prostate cancer after PSMA- or Choline-PET/CT: Operative and early oncological results

2018 ◽  
Vol 17 (2) ◽  
pp. e577-e578 ◽  
Author(s):  
J. Linxweiler ◽  
M. Saar ◽  
Z. Al-Kailani ◽  
M. Stöckle ◽  
S. Siemer ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Lymph Node ◽  
Lymph Node Dissection ◽  
Node Dissection ◽  
Choline Pet ◽  
Pet Ct ◽  
Salvage Lymph Node Dissection ◽  
Oncological Results

scholarly journals Diagnostic Accuracy of Ga-68-HBED-CC-PSMA-Ligand-PET/CT before Salvage Lymph Node Dissection for Recurrent Prostate Cancer

Theranostics ◽  
2017 ◽  
Vol 7 (6) ◽  
pp. 1770-1780 ◽  
Author(s):  
Cordula A. Jilg ◽  
Vanessa Drendel ◽  
H. Christian Rischke ◽  
Teresa Beck ◽  
Werner Vach ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Lymph Node ◽  
Diagnostic Accuracy ◽  
Lymph Node Dissection ◽  
Recurrent Prostate Cancer ◽  
Node Dissection ◽  
Psma Ligand ◽  
Pet Ct ◽  
Salvage Lymph Node Dissection

PD15-07 ASSESSING THE OPTIMAL EXTENT OF SALVAGE LYMPH NODE DISSECTION IN PATIENTS WITH SINGLE PELVIC NODAL UPTAKE AT [11C]-CHOLINE PET/CT SCAN FROM RECURRING PROSTATE CANCER

2014 ◽  
Vol 191 (4S) ◽  
Author(s):  
Niccolò Maria Passoni ◽  
Andrea Gallina ◽  
Ettore Di Trapani ◽  
Giorgio Gandaglia ◽  
Alessandro Larcher ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Lymph Node ◽  
Ct Scan ◽  
Lymph Node Dissection ◽  
Node Dissection ◽  
Choline Pet ◽  
Pet Ct ◽  
Salvage Lymph Node Dissection ◽  
Pet Ct Scan

scholarly journals MP79-02 PERFORMANCE CHARACTERISTICS OF PET/CT SCAN IN MEN TREATED WITH SALVAGE LYMPH NODE DISSECTION FOR RECURRENT PROSTATE CANCER

2020 ◽  
Vol 203 ◽  
pp. e1215-e1216
Author(s):  
Carlo Bravi* ◽  
Nicola Fossati ◽  
Giovanni Motterle ◽  
Jeffrey Karnes ◽  
Maximilian Schmautz ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Lymph Node ◽  
Ct Scan ◽  
Lymph Node Dissection ◽  
Performance Characteristics ◽  
Recurrent Prostate Cancer ◽  
Node Dissection ◽  
Pet Ct ◽  
Salvage Lymph Node Dissection ◽  
Pet Ct Scan
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