The Appendicitis Inflammatory Response Score: A Tool for the Diagnosis of Acute Appendicitis that Outperforms the Alvarado Score

2008 ◽  
Vol 32 (8) ◽  
pp. 1843-1849 ◽  
Author(s):  
Manne Andersson ◽  
Roland E. Andersson
Keyword(s):  
Inflammatory Response ◽  
Acute Appendicitis ◽  
Alvarado Score ◽  
Response Score

scholarly journals Predicting acute appendicitis? A prospective comparison of the Alvarado score, the Appendicitis Inflammatory Response score and clinical assessment

2014 ◽  
Vol 12 ◽  
pp. S94
Author(s):  
Damian McCartan ◽  
Daniel Kollar ◽  
Michael Bourke ◽  
K.S. Cross ◽  
Joseph Dowdall
Keyword(s):  
Inflammatory Response ◽  
Acute Appendicitis ◽  
Clinical Assessment ◽  
Alvarado Score ◽  
Prospective Comparison ◽  
Response Score

Evaluation of the Appendicitis Inflammatory Response Score against Alvarado Score in Diagnosis of Acute Appendicitis

2020 ◽  
Vol 18 (2) ◽  
pp. 68-72
Author(s):  
O.B. Karki ◽  
N.K. Hazra
Keyword(s):  
Inflammatory Response ◽  
Acute Appendicitis ◽  
Scoring System ◽  
Receiver Operating Curve ◽  
P Value ◽  
Diagnostic Challenge ◽  
Alvarado Score ◽  
Predictive Values ◽  
Suspected Appendicitis ◽  
Response Score

Background Patients presenting with suspected appendicitis pose a diagnostic challenge. Various scoring systems have been designed to aid in the clinical assessment of these patients. Widely applied was Alvarado score and best performed in validating studies, but was observed with few drawbacks. Appendicitis inflammatory response (AIR) score was designed to overcome the drawbacks associated with the implementation of Alvarado scoring system. Objective The main objective of this study was to evaluate the Appendicitis inflammatory Response Score and compare its performance in predicting risk of appendicitis with the Alvarado score. Method Appendicitis inflammatory response score and Alvarado scores were calculated prospectively on patients suspected of acute appendicitis presenting to Manipal Teaching Hospital, Pokhara, Nepal between July 2017 and June 2019. Diagnostic performance of the two scores was compared. Statistical analysis was done using SPSS 21 and p value < 0.05 was considered significant. Result The study included 217 patients with 109 (50.2%) males and 108 (49.8%) females. The mean age of patients was 25.77±15.54. The results analyzed showed better sensitivity of Appendicitis Inflammatory Response score (96.91%) as compared to 94.30% of Alvarado score. The positive and negative predictive values of Alvarado score were 74.87% and 50%, as compared to 79.70% and 72.20% for AIR score. Furthermore, the area under receiver operating curve of the appendix inflammatory response score was better (0.701) than that of Alvarado score (0.580). Conclusion Appendicitis Inflammatory Response (AIR) scoring performed well and more accurate than Alvarado scoring system with high specificity and high negative predictive value preventing negative appendectomies.

Predicting Acute Appendicitis? A comparison of the Alvarado Score, the Appendicitis Inflammatory Response Score and Clinical Assessment

2014 ◽  
Vol 39 (1) ◽  
pp. 104-109 ◽  
Author(s):  
D. Kollár ◽  
D. P. McCartan ◽  
M. Bourke ◽  
K. S. Cross ◽  
J. Dowdall
Keyword(s):  
Inflammatory Response ◽  
Acute Appendicitis ◽  
Clinical Assessment ◽  
Alvarado Score ◽  
Response Score

scholarly journals Erratum to: Predicting Acute Appendicitis? A Comparison of the Alvarado Score, the Appendicitis Inflammatory Response Score and Clinical Assessment

2014 ◽  
Vol 39 (1) ◽  
pp. 112-112 ◽  
Author(s):  
D. Kollár ◽  
D. P. McCartan ◽  
M. Bourke ◽  
K. S. Cross ◽  
J. Dowdall
Keyword(s):  
Inflammatory Response ◽  
Acute Appendicitis ◽  
Clinical Assessment ◽  
Alvarado Score ◽  
Response Score

scholarly journals Appendicitis inflammatory response score: a novel scoring system for acute appendicitis

2017 ◽  
Vol 4 (3) ◽  
pp. 1065
Author(s):  
Suresh Patil ◽  
Rahul Harwal ◽  
Sharanabasappa Harwal ◽  
Sangamesh Kamthane
Keyword(s):  
Inflammatory Response ◽  
Acute Appendicitis ◽  
Scoring Systems ◽  
Alvarado Score ◽  
Lower Quadrant ◽  
Negative Laparotomy ◽  
Surgical Emergencies ◽  
Prospective Comparative Study ◽  
The Right ◽  
Response Score

Background: Acute appendicitis is one of the most common surgical emergencies encountered by doctors on call with emergency appendicectomy being a very common outcome of emergency laparotomies. There's been a marked decline in mortality over the past 50 years, but the rates of perforation and negative laparotomy have not changed much as they're influenced by factors untouched by technological advances.Methods: A prospective comparative study to compare appendicitis inflammatory response score (AIR) and Alvarado scoring systems in evaluating suspected cases of acute appendicitis. 100 patients presenting with pain in the right lower quadrant of abdomen at the surgical clinics at Basaveshwar Teaching and General Hospital, Kalaburagi, Karnataka, India, who after clinical examination and relevant investigations were provisionally diagnosed to have acute appendicitis and warranted surgery for the same were evaluated using the scoring systems - Alvarado Score and Appendicitis Inflammatory Response Score. The scores were tallied and compared with final histopathology report. The study was conducted for a period of one and a half year.Results: The results revealed that AIR (at score >4) demonstrated a higher sensitivity and specificity compared to Alvarado score (89.9 versus 78.6%) and (63.6 versus 54.5) respectively. Alvarado showed a slightly better sensitivity at score>8 (21.3 versus 12.3%).Conclusions: The Appendicitis Inflammatory Response Score outperformed the Alvarado score. It holds promise to be incorporated into the clinician's daily inventory in efficiently diagnosing Appendicitis.

scholarly journals Evaluation of the Appendicitis Inflammatory Response Score for Patients with Acute Appendicitis

2012 ◽  
Vol 36 (7) ◽  
pp. 1540-1545 ◽  
Author(s):  
S. M. M. de Castro ◽  
Ç. Ünlü ◽  
E. Ph. Steller ◽  
B. A. van Wagensveld ◽  
B. C. Vrouenraets
Keyword(s):  
Inflammatory Response ◽  
Acute Appendicitis ◽  
Response Score

scholarly journals Evaluación de la Escala de Alvarado versus Score de Respuesta Inflamatoria de la Apendicitis, Hospital José Carrasco Arteaga 2018

2020 ◽  
Vol 12 (2) ◽  
pp. 112
Author(s):  
Jorge Roberto Rodas Andrade ◽  
Marco Vinicio Urgilés Rivas ◽  
Julio Cesar Ordoñez Cumbe ◽  
Karla Marisela Cabrera Abad ◽  
Patricia Piedad Naulaguari Medina
Keyword(s):  
Acute Appendicitis ◽  
Likelihood Ratio ◽  
Roc Curve ◽  
Predictive Value ◽  
Test Validity ◽  
Public Health Issue ◽  
Alvarado Score ◽  
Cross Sectional ◽  
Modified Alvarado Score ◽  
Response Score

BACKGROUND: Acute appendicitis is the main cause of non-traumatic acute abdomen worldwide, it is still a public health issue and the diagnosis can be challenging. When an atypical case is presented, is necessary to use diagnostic scores, like Alvarado Score, Modified Alvarado Score, RIPASA, among others. The aim of this study was to determine the test validity of Inflammatory Response Score versus Alvarado Score, for acute appendicitis diagnosis in 16 year old and older patients. METHODS: This is a descriptive, cross-sectional, validity test study, to compare AIR Score and Alvarado Score, with the Gold-Standard histopathology results. A sample of 292 patients that went under appendectomy at Hospital José Carrasco Arteaga during 2018 was studied. We considered sensitivity, specificity, positive predictive value (PPV), negative predictive value (VPN), ROC curve and Likelihood Ratio. RESULTS: 49.7% patients were young adults, 62.7% of the patients were male. Alvarado Score showed a 88.5% sensitivity, 29.6% specificity, PPV of 81.7%, 42.2% NPV, 1.23 LR+ and 0.38 –LR; compared to 94.7% sensitivity, 76.5% specificity, 93.5% PPV, 80.3% NPV, 4.02 +LR, 0.611 -LR for Appendicitis Immflamatory Response Score. ROC curve for AIRS was 0.897, higher than Alvarado Score (0.611); being AIRS a more precise diagnostic test than Alvarado Score. CONCLUSIÓN: AIRS showed higher sensitivity (94.7%) and specificity (76.5%) than Alvarado Score (88.5%, 29.6% respectively). Alvarado Score is sensitive enough for acute appendicitis diagnosis, but not specific enough to exclude the diagnosis. AIRS shows a higher Likelihood Ratio and ROC curve than Alvarado Score, but the posttest probability is low for identifying acute appendicitis cases.

Sign in / Sign up

Export Citation Format

Share Document