Incidence and Risk Factors of the Intraoperative Localization Failure of Nonpalpable Breast Lesions by Radio-guided Occult Lesion Localization: A Retrospective Analysis of 579 Cases: Reply

2012 ◽  
Vol 37 (2) ◽  
pp. 476-477 ◽  
Author(s):  
Emily L. Postma ◽  
Helena M. Verkooijen ◽  
Maurice A. A. J. van den Bosch ◽  
Richard van Hillegersberg
2019 ◽  
Vol 179 (3) ◽  
pp. 671-676 ◽  
Author(s):  
Nicole Look Hong ◽  
Frances C. Wright ◽  
Mark Semple ◽  
Alexandru M. Nicolae ◽  
Ananth Ravi

Abstract Purpose Magnetic Occult Lesion Localization Instrument (MOLLI) is a wireless, non-radioactive alternative for non-palpable breast lesion localization. The primary objective of this first-in-human study was to evaluate the clinical feasibility of using MOLLI for intraoperative localization of non-palpable breast lesions. Methods Twenty women with non-palpable breast lesions at a single institution received a lumpectomy using the MOLLI guidance system. Patients were co-localized with magnetic and radioactive markers up to 7 days before excision by a dedicated breast radiologist under sonographic guidance. Both markers were localized intraoperatively using dedicated hand-held probes. The primary outcome was successful excision of the magnetic marker, confirmed radiographically and pathologically. Demographic data, margin positivity, and re-excision rates were collected. Surgical oncologists, radiologists, and pathology staff were surveyed for user satisfaction. Results Post-radiological analysis: Post-implant mammograms verified that 17/20 markers were placed directly in the lesion center. Radiologists reported that all marker implantations procedures were “easy” or “very easy” following a single training session. Post-surgical analysis: All MOLLI markers were successfully removed with the specimen during surgical excision. In all cases, surgeons ranked the MOLLI guidance system as “very easy” for lesion localization. Pathologic analysis: All patients had negative margins. All anatomic pathology staff ranked the MOLLI system as “very easy” to localize markers. Conclusions The MOLLI guidance system is a reliable and accurate method for intraoperative localization of non-palpable breast lesions. Further evaluation of the MOLLI system in studies against current standards of care is required to demonstrate system cost-effectiveness and improved patient-reported outcomes.


2017 ◽  
Vol Special iss (5) ◽  
Author(s):  
Ali Alamdaran ◽  
Ramin Sadegi ◽  
Aida Sharifi ◽  
Elaheh Moododi ◽  
Naser Forghani

2018 ◽  
Vol 51 (3) ◽  
pp. 147-150 ◽  
Author(s):  
Chiang Jeng Tyng ◽  
Paula Nicole Vieira Pinto Barbosa ◽  
Almir Galvão Vieira Bitencourt ◽  
Maurício Kauark Amoedo ◽  
Maria Fernanda Arruda Almeida ◽  
...  

Abstract Objective: To describe the preoperative localization of musculoskeletal lesions with the radioguided occult lesion localization (ROLL) technique. Materials and Methods: In all cases, computed tomography-guided injection of technetium-99m sulfur colloid was performed, directly into or near the suspicious lesion, up to 36 hours before the surgical procedure. Lesions were detected intraoperatively with a gamma probe. Results: We report the cases of six patients submitted to radioguided surgery, including three patients with bone lesions suspicious for metastasis, two patients suspected of recurrent sarcoma, and one patient with no previous diagnosis who had a nodular lesion on the left leg. Patients tolerated the procedure well, and no complications were associated with the puncture. All marked lesions were easily identified intraoperatively and were excised with clear margins. Conclusion: The ROLL technique was effective in the intraoperative localization of occult musculoskeletal lesions, demonstrating that it is a feasible and promising technique for the surgical exploration of selected cases.


The Breast ◽  
2011 ◽  
Vol 20 (3) ◽  
pp. 241-245 ◽  
Author(s):  
Fatih Aydogan ◽  
Volkan Ozben ◽  
Mehmet Halit Yilmaz ◽  
Varol Celik ◽  
Cihan Uras ◽  
...  

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