The Efficacy and Safety of High-Intensity Focused Ultrasound (HIFU) Therapy for Benign Thyroid Nodules—A Single Center Experience from Singapore

2019 ◽  
Vol 43 (8) ◽  
pp. 1957-1963 ◽  
Author(s):  
Prajwala S. Prakash ◽  
Han Boon Oh ◽  
Wee Boon Tan ◽  
Rajeev Parameswaran ◽  
Kee Yuan Ngiam
Keyword(s):  
High Intensity ◽  
Focused Ultrasound ◽  
Thyroid Nodules ◽  
High Intensity Focused Ultrasound ◽  
Efficacy And Safety ◽  
Single Center ◽  
Single Center Experience ◽  
Benign Thyroid Nodules ◽  
Benign Thyroid

Efficacy and safety of high-intensity focused ultrasound (HIFU) for treating benign thyroid nodules: a systematic review and meta-analysis

2020 ◽  
Vol 61 (12) ◽  
pp. 1636-1643 ◽  
Author(s):  
Sae Rom Chung ◽  
Jung Hwan Baek ◽  
Chong Hyun Suh ◽  
Young Jun Choi ◽  
Jeong Hyun Lee
Keyword(s):  
Systematic Review ◽  
High Intensity ◽  
Focused Ultrasound ◽  
Thyroid Nodules ◽  
Meta Analysis ◽  
High Intensity Focused Ultrasound ◽  
Efficacy And Safety ◽  
Inconsistency Index ◽  
Benign Thyroid Nodules ◽  
Benign Thyroid

Background High-intensity focused ultrasound (HIFU) is an emerging thermal ablation technique that has been successfully applied to various benign thyroid nodules. Purpose To evaluate the efficacy and safety of HIFU for the treatment of benign thyroid nodules. Material and Methods The Ovid-MEDLINE and EMBASE databases were searched up to 9 July 2018 for studies describing the use of HIFU to treat benign thyroid nodules. We included studies that have outcomes with sufficient detail to evaluate the volume reduction rate (VRR). The pooled proportions of VRR ≥50% and pooled VRR at one, three, and six months after HIFU were assessed using random-effects modeling. Heterogeneity among studies was determined using Chi-square statistics for pooled estimates and the inconsistency index I2. Results Seven studies were included in the systematic review and four in the meta-analysis. The pooled VRR at one, three, and six months after HIFU were 17.59 (95% confidence interval [CI] 12.56–22.62), 48.93 (95% CI 42.20–55.66), and 60.43 (95% CI 51.88–68.98). The pooled proportions of VRR ≥50% at six months after HIFU were 75% (95% CI 53–89; I2=73.6%). There were no major complications of HIFU. Conclusion HIFU may be a safe and effective treatment modality for benign thyroid nodules, especially for small nodules.

Single-session high-intensity focused ultrasound (HIFU) ablation for benign thyroid nodules: a systematic review

2020 ◽  
Vol 17 (8) ◽  
pp. 759-771
Author(s):  
Eleftherios Spartalis ◽  
Sotirios P. Karagiannis ◽  
Nikolaos Plakopitis ◽  
Maria Anna Theodori ◽  
Dimosthenis Chrysikos ◽  
...  
Keyword(s):  
Systematic Review ◽  
High Intensity ◽  
Focused Ultrasound ◽  
Thyroid Nodules ◽  
High Intensity Focused Ultrasound ◽  
Single Session ◽  
Hifu Ablation ◽  
Benign Thyroid Nodules ◽  
Benign Thyroid

High-intensity focused ultrasound (HIFU) for benign thyroid nodules: 2-year follow-up results

Endocrine ◽  
2019 ◽  
Vol 65 (2) ◽  
pp. 312-317 ◽  
Author(s):  
Pierpaolo Trimboli ◽  
Federico Pelloni ◽  
Fabiano Bini ◽  
Franco Marinozzi ◽  
Luca Giovanella
Keyword(s):  
High Intensity ◽  
Focused Ultrasound ◽  
Thyroid Nodules ◽  
High Intensity Focused Ultrasound ◽  
Benign Thyroid Nodules ◽  
Benign Thyroid
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