Association between acute myeloid leukemia and isochromosome 6p: a case study and review of the literature

2010 ◽  
Vol 89 (12) ◽  
pp. 1283-1285
Author(s):  
Seung Hwan Oh ◽  
Tae Sung Park ◽  
So Young Kim ◽  
Gayoung Lim ◽  
Si Hyun Kim ◽  
...  
2011 ◽  
Vol 126 (4) ◽  
pp. 195-198 ◽  
Author(s):  
Sang-Guk Lee ◽  
Tae Sung Park ◽  
Seung Hwan Oh ◽  
Ji Chan Park ◽  
Young Joon Yang ◽  
...  

2014 ◽  
Vol 2014 ◽  
pp. 1-4 ◽  
Author(s):  
Pankit Vachhani ◽  
Prithviraj Bose

Myeloid sarcoma represents the proliferation of myeloblasts of acute myeloid leukemia (AML) at extramedullary sites. While extramedullary involvement in AML is uncommon in itself, isolated myeloid sarcomas, that is, myeloid sarcomas without any bone marrow involvement, are extremely rare and pose a diagnostic and therapeutic challenge. Here, we present the case of a middle-aged woman with isolated myeloid sarcoma in the stomach—an organ seldom involved by this disease. Additionally, the literature on the epidemiology, diagnosis, pathology, prognosis, and therapeutic options in myeloid sarcomas has been reviewed.


Leukemia ◽  
2001 ◽  
Vol 15 (10) ◽  
pp. 1668-1670 ◽  
Author(s):  
N Viniou ◽  
E Terpos ◽  
J Rombos ◽  
G Vaiopoulos ◽  
K Nodaros ◽  
...  

2010 ◽  
Vol 196 (1) ◽  
pp. 105-108 ◽  
Author(s):  
Il Joong Park ◽  
Jun Eun Park ◽  
Hyon Joo Kim ◽  
Hyun Joo Jung ◽  
Wee Gyo Lee ◽  
...  

Blood ◽  
2008 ◽  
Vol 112 (11) ◽  
pp. 4018-4018
Author(s):  
Chunyan Wang ◽  
Huo Tan ◽  
SiDa Peng ◽  
ZhenQian Huang

Abstract Extramedullary relapse is a pattern of acute myeloid leukemia (AML) relapse post-allogeneic hematopoietic stem cell transplantation (alloHSCT). We present the case of a 43-year-old female patient with acute mix cell leukemia who had isolated extramedullary relapse develop in both breasts 2 years after alloHSCT, the first reported case in adult patients in the literature to the best of our knowledge. She received further chemotherapy with pemetrexed (Alimta) intravenous injection (500mg/D1, every 3 weeks is one course of treatment). After 2 courses of treatments, her swelled breasts were shrunk remarkably and no obvious side effects were found. We therefore conclude that pemetrexed treatment may be an effective regimen for breast extramedullary leukemia. Review of the literature about extramedullary relapse and breast involvement as well as the treatment of these cases were further discussed.


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