Role of chemotherapy in the treatment of metastatic castration-resistant prostate cancer patients who have progressed after abiraterone acetate

2015 ◽  
Vol 76 (3) ◽  
pp. 439-445 ◽  
Author(s):  
Roberto Petrioli ◽  
Edoardo Francini ◽  
Letizia Laera ◽  
Anna Ida Fiaschi ◽  
Roberto Ponchietti ◽  
...  

2020 ◽  
Vol 72 (6) ◽  
Author(s):  
Consuelo Buttigliero ◽  
Marcello Tucci ◽  
Cristina Sonetto ◽  
Francesca Vignani ◽  
Rosario F. Di Stefano ◽  
...  




2020 ◽  
Vol 3 (1) ◽  
pp. 119-127 ◽  
Author(s):  
Eleni Efstathiou ◽  
Mark Titus ◽  
Sijin Wen ◽  
Patricia Troncoso ◽  
Anh Hoang ◽  
...  






2021 ◽  
Vol 11 ◽  
Author(s):  
Anne-Emmanuella Yeo ◽  
Aurore Hendrix ◽  
Caterina Confente ◽  
Nicolas Christian ◽  
Baudouin Mansvelt ◽  
...  

Metastatic prostate cancer remains a challenge for clinicians. Metastases involve mainly the bone compartment and can manifest as oligometastatic disease. In this setting, the role of metastasis-directed therapies (MDT) including surgery and/or stereotactic body radiotherapy is currently evaluated. Visceral metastases are less common and have very poor prognosis in mPC. Whether treating isolated visceral metastases such as liver metastases with MDT could increase the prognosis remains unknown. We report the management of a prostate cancer patient who progressed on androgen deprivation therapy with apparition of two liver metastases. We describe the feasibility of combining MDT with abiraterone acetate and prednisone in a patient with metastatic castration-resistant prostate cancer. MDT allowed the interruption of abiraterone acetate, preventing cumulative toxicity of this agent.



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