Impact of surgical wait times during summer months on the oncological outcomes following robotic-assisted radical prostatectomy: 10 years’ experience from a large Canadian academic center

2020 ◽  
Author(s):  
Ahmed S. Zakaria ◽  
Félix Couture ◽  
David-Dan Nguyen ◽  
Côme Tholomier ◽  
Hanna Shahine ◽  
...  
Keyword(s):  
Radical Prostatectomy ◽  
Wait Times ◽  
Robotic Assisted ◽  
Oncological Outcomes ◽  
Academic Center ◽  
Robotic Assisted Radical Prostatectomy

scholarly journals MP74-18 IMPACT OF SURGICAL WAIT TIMES DURING SUMMER MONTHS ON THE ONCOLOGICAL OUTCOMES FOLLOWING ROBOTIC-ASSISTED RADICAL PROSTATECTOMY

2020 ◽  
Vol 203 ◽  
pp. e1138-e1139
Author(s):  
Ahmed Sayed Zakaria* ◽  
Félix Couture ◽  
David-Dan Nguyen ◽  
Hanna Shahine ◽  
Côme Tholomier ◽  
...  
Keyword(s):  
Radical Prostatectomy ◽  
Wait Times ◽  
Robotic Assisted ◽  
Oncological Outcomes ◽  
Robotic Assisted Radical Prostatectomy

Oncological outcomes following robotic-assisted radical prostatectomy in a multiracial Asian population

2015 ◽  
Vol 9 (3) ◽  
pp. 201-209 ◽  
Author(s):  
Low Wei Xiang Alvin ◽  
Sim Hong Gee ◽  
Huang Hong Hong ◽  
Cheng Wai Sam Christopher ◽  
Ho Sien Sun Henry ◽  
...  
Keyword(s):  
Radical Prostatectomy ◽  
Asian Population ◽  
Robotic Assisted ◽  
Oncological Outcomes ◽  
Robotic Assisted Radical Prostatectomy

Oncological outcomes of robotic-assisted radical prostatectomy after more than 5 years

2013 ◽  
Vol 32 (2) ◽  
pp. 413-418 ◽  
Author(s):  
Michele Billia ◽  
Oussama Elhage ◽  
Benjamin Challacombe ◽  
Declan Cahill ◽  
Rick Popert ◽  
...  
Keyword(s):  
Radical Prostatectomy ◽  
Robotic Assisted ◽  
Oncological Outcomes ◽  
Robotic Assisted Radical Prostatectomy

NeuroSAFE PROOF: study protocol for a single-blinded, IDEAL stage 3, multi-centre, randomised controlled trial of NeuroSAFE robotic-assisted radical prostatectomy versus standard robotic-assisted radical prostatectomy in men with localized prostate cancer.

2022 ◽  
Author(s):  
Eoin Dinneen ◽  
Jack Grierson ◽  
Ricardo Almeida Magana ◽  
Rosie Clow ◽  
Aiman Haider ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Radical Prostatectomy ◽  
Frozen Section ◽  
Controlled Trial ◽  
Robotic Assisted ◽  
Oncological Outcomes ◽  
The World ◽  
Robotic Assisted Radical Prostatectomy ◽  
Randomised Controlled

Abstract BackgroundRobotic radical prostatectomy (RARP) is a first-line curative treatment option for localized prostate cancer. Postoperative erectile dysfunction and urinary incontinence are common associated adverse side effects that can negatively impact patients’ quality of life. Preserving the lateral neurovascular bundles (NS) during RARP improves functional outcomes. However, selecting men for NS may be difficult when there is concern about incurring in positive surgical margin (PSM) which in turn risks adverse oncological outcomes. The NeuroSAFE technique (intra-operative frozen section examination of the neurovascular structure adjacent prostate margin) can provide real-time pathological consult to promote optimal NS while avoiding PSM.MethodsNeuroSAFE PROOF is a single-blinded, multi-centre, randomised controlled trial (RCT) in which men are randomly allocated 1:1 to either NeuroSAFE RARP or standard RARP. Men electing for RARP as primary treatment, who are continent and have good baseline erectile function (EF), defined by International Index of Erectile Function (IIEF-5) score>21, are eligible. NS in the intervention arm is guided by the NeuroSAFE technique. NS in the standard arm is based on standard of care, i.e., a pre-operative image-based planning meeting, patient-specific clinical information, and digital rectal examination. The primary outcome is assessment of EF at 12-months. The primary endpoint is the proportion of men who achieve IIEF-5 score ≥ 21. A sample size of 404 was calculated to give a power of 90% to detect a difference of 14% between groups based on a feasibility study. Oncological outcomes are continuously monitored by an independent Data Monitoring Committee. Key secondary outcomes include urinary continence at 3 months assessed by the international consultation on incontinence questionnaire, rate of biochemical recurrence, EF recovery at 24-months, and difference in quality of life.DiscussionThe NeuroSAFE PROOF is the first RCT of intra-operative frozen section in radical prostatectomy in the world. It is properly powered to evaluate a difference in the recovery of EF for men undergoing RARP assessed by patient reported outcome measures. It will provide evidence to guide the use of the NeuroSAFE technique around the world.Trial registration: NCT03317990 (23 October 2017). Regional Ethics Committee; reference 17/LO/1978.

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