Diffuse leptomeningeal glioneuronal tumor (DLGNT) mimicking Whipple’s disease: a case report and literature review

2017 ◽  
Vol 33 (8) ◽  
pp. 1411-1414 ◽  
Author(s):  
Vega Karlowee ◽  
Manish Kolakshyapati ◽  
Vishwa Jeet Amatya ◽  
Takeshi Takayasu ◽  
Ryo Nosaka ◽  
...  
Keyword(s):  
Case Report ◽  
Literature Review ◽  
Glioneuronal Tumor ◽  
Whipple’S Disease ◽  
Whipple's Disease ◽  
Diffuse Leptomeningeal Glioneuronal Tumor

scholarly journals Diffuse leptomeningeal glioneuronal tumor with high-grade features masquerading as tubercular meningitis—a case report

2021 ◽  
Vol 52 (1) ◽  
Author(s):  
Sameer Peer ◽  
Vivek Murumkar ◽  
Karthik Kulanthaivelu ◽  
Chandrajit Prasad ◽  
Shilpa Rao ◽  
...  
Keyword(s):  
Case Report ◽  
Early Diagnosis ◽  
Histopathological Examination ◽  
Glioneuronal Tumor ◽  
Communicating Hydrocephalus ◽  
High Grade ◽  
Endemic Region ◽  
Tubercular Meningitis ◽  
Leptomeningeal Enhancement ◽  
Diffuse Leptomeningeal Glioneuronal Tumor

Abstract Background Diffuse leptomeningeal glioneuronal tumor (DLGNT) has been recently described in the literature. The complete neuroimaging spectrum and histopathological characteristics of this entity are yet to be elucidated. In an endemic region, diffuse leptomeningeal enhancement on neuroimaging with associated communicating hydrocephalus is usually suggestive of infective meningitis and the patients are started on empirical anti-microbial therapy. However, it is important to consider other differential diagnosis of leptomeningeal enhancement in such cases, particularly if the clinical condition does not improve on anti-microbial therapy. An early diagnosis of a neoplastic etiology may be of particular importance as the treatment regimens vary considerably depending on the underlying disease condition. Case presentation In this case report, we describe a case of DLGNT with high-grade histopathological features which was initially managed as tubercular meningitis based on the initial neuroimaging findings. Due to worsening of the clinical course and subsequent imaging findings at follow-up, a diagnosis of DLGNT was considered and subsequently proven to be DLGNT with features of anaplasia on histopathological examination of leptomeningeal biopsy specimen. Conclusion This case highlights the importance of recognizing certain subtle finding on MRI which may help in an early diagnosis of DLGNT which is crucial for appropriate treatment.

Whipple’s Disease: a Case Report Spanning 20 Years

2021 ◽  
Vol 3 (5) ◽  
pp. 1210-1214
Author(s):  
Isabel Furtado ◽  
Maria Trepa ◽  
Tomás Fonseca ◽  
Agostinho Sanchez ◽  
Diogo Rijo ◽  
...  
Keyword(s):  
Case Report ◽  
Whipple’S Disease ◽  
Whipple's Disease

scholarly journals Rosette-forming glioneuronal tumor of the aqueduct of Sylvius: Case report and literature review

2020 ◽  
Vol 19 ◽  
pp. 100584
Author(s):  
Mohammad Saad Asif ◽  
Ioana D. Moldovan ◽  
Fahad Alkherayf
Keyword(s):  
Case Report ◽  
Literature Review ◽  
Glioneuronal Tumor ◽  
Aqueduct Of Sylvius

scholarly journals A multimodal staged approach for the resection of a Sylvian aqueduct rosette-forming glioneuronal tumor: A case report and literature review

2019 ◽  
Vol 16 ◽  
pp. 95-100 ◽  
Author(s):  
Giannantonio Spena ◽  
Pier Paolo Panciani ◽  
Pier Paolo Mattogno ◽  
Elena Roca ◽  
Pietro Luigi Poliani ◽  
...  
Keyword(s):  
Case Report ◽  
Literature Review ◽  
Glioneuronal Tumor ◽  
Staged Approach

scholarly journals Malignant Transformation of a Rosette-Forming Glioneuronal Tumor with IDH1 Mutation: A Case Report and Literature Review

2019 ◽  
Vol 2 ◽  
pp. 100006 ◽  
Author(s):  
Ronie Romelean Jayapalan ◽  
Kein Seong Mun ◽  
Kum Thong Wong ◽  
Sheau Fung Sia
Keyword(s):  
Case Report ◽  
Literature Review ◽  
Malignant Transformation ◽  
Idh1 Mutation ◽  
Glioneuronal Tumor

Whipple's disease: An uncommon cause of mesenteric lymphadenopathy – A case report

Pathology ◽  
2018 ◽  
Vol 50 ◽  
pp. S75
Author(s):  
Maryam Jabripoor ◽  
Kenneth Tang ◽  
Charmaine Wong ◽  
Wieslawa Wielebinski
Keyword(s):  
Case Report ◽  
Whipple’S Disease ◽  
Whipple's Disease
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