Total mesorectal excision with and without lateral lymph node dissection: a systematic review of the literature

2020 ◽  
Vol 35 (7) ◽  
pp. 1183-1192
Author(s):  
Gregoire Longchamp ◽  
Jeremy Meyer ◽  
Niki Christou ◽  
Sotirios Popeskou ◽  
Elin Roos ◽  
...  
Keyword(s):  
Systematic Review ◽  
Lymph Node ◽  
Total Mesorectal Excision ◽  
Lymph Node Dissection ◽  
Lateral Lymph Node Dissection ◽  
Review Of The Literature ◽  
Node Dissection ◽  
Mesorectal Excision ◽  
Lateral Lymph Node

scholarly journals Lateral lymph node dissection for mid-to-low rectal cancer: is it safe and effective in a practice-based cohort?

BMC Surgery ◽  
2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Masakatsu Numata ◽  
Hiroshi Tamagawa ◽  
Keisuke Kazama ◽  
Shinnosuke Kawahara ◽  
Sho Sawazaki ◽  
...  
Keyword(s):  
Rectal Cancer ◽  
Lymph Node ◽  
Lymph Node Dissection ◽  
Outcome Evaluation ◽  
Low Rectal Cancer ◽  
Lateral Lymph Node Dissection ◽  
Node Dissection ◽  
Mesorectal Excision ◽  
Lateral Lymph Node ◽  
R1 Resection

Abstract Background Most evidence regarding lateral lymph node dissection for rectal cancer is from expert settings. This study aimed to evaluate the safety and efficacy of this procedure in a practice-based cohort. Methods A total of 383 patients who were diagnosed with stage II–III mid-to-low rectal cancer between 2010 and 2019 and underwent primary resection with curative intent at a general surgery unit were retrospectively reviewed. After propensity matching, 144 patients were divided into the following groups for short- and long-term outcome evaluation: mesorectal excision with lateral lymph node dissection (n = 72) and mesorectal excision (n = 72). Results This practice-based cohort was characterized by a high pT4 (41.6%) and R1 resection (10.4%) rate. Although the operative time was longer in the lateral dissection group (349 min vs. 237 min, p < 0.001), postoperative complications (19.4% vs. 16.7%, p = 0.829), and hospital stay (18 days vs. 22 days, p = 0.059) did not significantly differ; 5-year relapse-free survival (62.5% vs. 66.4%, p = 0.378), and cumulative local recurrence (9.7% vs. 15.3%, p = 0.451) were also in the same range in both groups. In the seven locally recurrent cases in the lateral dissection group, four had undergone R1 resection. Conclusions Lateral lymph node dissection was found to be safe in this practice-based cohort; however, the local control effect was not obvious. To maximize the potential merits of lateral lymph node dissection, strategies need to be urgently established to avoid R1 resection in clinical practice.

Mesorectal Excision With or Without Lateral Lymph Node Dissection for Clinical Stage II/III Lower Rectal Cancer (JCOG0212)

2017 ◽  
Vol 266 (2) ◽  
pp. 201-207 ◽  
Author(s):  
Shin Fujita ◽  
Junki Mizusawa ◽  
Yukihide Kanemitsu ◽  
Masaaki Ito ◽  
Yusuke Kinugasa ◽  
...  
Keyword(s):  
Rectal Cancer ◽  
Lymph Node ◽  
Lymph Node Dissection ◽  
Clinical Stage ◽  
Stage Ii ◽  
Lateral Lymph Node Dissection ◽  
Lower Rectal Cancer ◽  
Node Dissection ◽  
Mesorectal Excision ◽  
Lateral Lymph Node
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