Influence of molar mass, dispersity, and type and location of hydrophobic side chain moieties on the critical micellar concentration and stability of amphiphilic HPMA-based polymer drug carriers

2017 ◽  
Vol 295 (8) ◽  
pp. 1313-1325 ◽  
Author(s):  
Sergey K. Filippov ◽  
Natalya S. Vishnevetskaya ◽  
Bart-Jan Niebuur ◽  
Eva Koziolová ◽  
Ekaterina A. Lomkova ◽  
...  
Keyword(s):  
Molar Mass ◽  
Drug Carriers ◽  
Critical Micellar Concentration ◽  
Side Chain

Phase behavior of side-chain liquid-crystalline polymers containing biphenyl mesogens with different spacer lengths synthesized via miniemulsion polymerization

2016 ◽  
Vol 7 (29) ◽  
pp. 4736-4750 ◽  
Author(s):  
Ehsan Mehravar ◽  
Amaia Iturrospe ◽  
Arantxa Arbe ◽  
José M. Asua ◽  
Jose R. Leiza
Keyword(s):  
Phase Behavior ◽  
Liquid Crystalline ◽  
Molar Mass ◽  
Miniemulsion Polymerization ◽  
Liquid Crystalline Polymers ◽  
Side Chain ◽  
High Molar Mass ◽  
Crystalline Polymers

High molar mass SCLCPs were synthesized by miniemulsion polymerization, and the phase behavior of the polymers was investigated by a combination of DSC, PLM, SAXS and WAXS.

scholarly journals Initiation of RAFT Polymerization: Electrochemically Initiated RAFT Polymerization in Emulsion (Emulsion eRAFT), and Direct PhotoRAFT Polymerization of Liquid Crystalline Monomers

2021 ◽  
Vol 74 (1) ◽  
pp. 56 ◽  
Author(s):  
Caroline Bray ◽  
Guoxin Li ◽  
Almar Postma ◽  
Lisa T. Strover ◽  
Jade Wang ◽  
...  
Keyword(s):  
Liquid Crystalline ◽  
Colloidal Stability ◽  
Molar Mass ◽  
Raft Polymerization ◽  
Monomer Conversion ◽  
Continuous Phase ◽  
Side Chain ◽  
Crystalline Polymers ◽  
Reversible Addition ◽  
Polymerization Conditions

We report on two important advances in radical polymerization with reversible addition–fragmentation chain transfer (RAFT polymerization). (1) Electrochemically initiated emulsion RAFT (eRAFT) polymerization provides rapid polymerization of styrene at ambient temperature. The electrolytes and mediators required for eRAFT are located in the aqueous continuous phase separate from the low-molar-mass-dispersity macroRAFT agent mediator and product in the dispersed phase. Use of a poly(N,N-dimethylacrylamide)-block-poly(butyl acrylate) amphiphilic macroRAFT agent composition means that no added surfactant is required for colloidal stability. (2) Direct photoinitiated (visible light) RAFT polymerization provides an effective route to high-purity, low-molar-mass-dispersity, side chain liquid-crystalline polymers (specifically, poly(4-biphenyl acrylate)) at high monomer conversion. Photoinitiation gives a product free from low-molar-mass initiator-derived by-products and with minimal termination. The process is compared with thermal dialkyldiazene initiation in various solvents. Numerical simulation was found to be an important tool in discriminating between the processes and in selecting optimal polymerization conditions.

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