Ranges of psychiatric morbidity in the old and the very old - results from the Berlin Aging Study (BASE)

2000 ◽  
Vol 250 (3) ◽  
pp. 111-119 ◽  
Author(s):  
T. F. Wernicke ◽  
Michael Linden ◽  
Reiner Gilberg ◽  
Hanfried Helmchen
2004 ◽  
Vol 16 (4) ◽  
pp. 461-480 ◽  
Author(s):  
Michael Linden ◽  
Thomas Bär ◽  
Hanfried Helmchen

Background: The aim of this epidemiological study is to examine the prevalence and correlates of psychotropic drug use in the very old and to evaluate the appropriateness of psychotropic drug use in very old age.Methods: Data from the Berlin Aging Study (BASE), a multidisciplinary study of an age- and gender-stratified, randomly selected sample of elderly people living in Berlin are presented. Over-sampling, especially very old men, allows for powerful analyses of this population. All participants went through extensive psychiatric and somatic examinations. Medication intake was assessed by different data sources (interviewing patients and their family physicians, drug inspection at home). Results were brought together in a consensus-conference and research physicians gave operationalized ratings of medication appropriateness.Results: The prevalence of elderly people who were taking at least one psychotropic medication within the 14 days immediately preceding investigation was 29.8%. Of these medications, 68.4% had been taken for longer than one year. There was no effect of age or gender on the scope of psychotropic drug use. Benzodiazepines were taken by 19.8% of the elderly. Antidepressants, neuroleptics and anti-dementia drugs were taken by about 3–4% each. People taking psychotropic drugs had significantly higher levels of psychiatric morbidity, as measured by syndromes and specified diagnoses. Psychotropic drugs were significantly less often judged to be indicated than somatic medications. This is mostly due to benzodiazepines.Conclusions: Psychotropic drug use is common in old age, but there is no additional increase in usage beyond the age of 70. Intake of psychotropics is mostly oriented at symptoms or syndromes, which explains why benzodiazepines are still the most commonly prescribed psychotropics


1993 ◽  
Vol 13 (4) ◽  
pp. 589-617 ◽  
Author(s):  
Hanfried Helmchen ◽  
Michael Linden

ABSTRACTKey questions in the psychiatric understanding of elderly people are the development of psychiatric morbidity, its phenomenology in old age, the differentiation between ‘normal’ and ‘pathological’ ageing, the interrelatedness of different types of mental disorders, their relation to somatic morbidity, and their consequences in daily life. Under the hypothesis of the de-differentiation of psychopathological features in old age, the relation between depression and dementia is studied. Contrary to most gerontopsychiatric research, the Berlin Aging Study (BASE) permits an analysis of these questions in a heterogeneous and primarily non-clinical community population. Initial data from the first 360 intake assessments and the first 156 intensively studied participants of BASE are presented. Results show that, even in very old individuals, depression and dementia still exhibit clearly distinctive psychopathological features. Prevalence rates in consecutive age groups show an age-related increase for dementia but not for depression. Nevertheless dementia and depression do not seem to be fully independent, because our data indicate a masking or extinction of depressive symptoms by dementia. Finally, both disorders have a similarly significant negative impact on independence, comparable to that of somatic morbidity.


1994 ◽  
Vol 19 ◽  
pp. 177-184
Author(s):  
R. Nieczaj ◽  
J.P. Fischer ◽  
M. Taupitz ◽  
M. Borchelt ◽  
E. Steinhagen-Thiessen

2003 ◽  
Vol 18 (2) ◽  
pp. 318-331 ◽  
Author(s):  
Tania Singer ◽  
Paul Verhaeghen ◽  
Paolo Ghisletta ◽  
Ulman Lindenberger ◽  
Paul B. Baltes
Keyword(s):  
Old Age ◽  
Very Old ◽  

2013 ◽  
Vol 32 ◽  
pp. S133
Author(s):  
N. Buchmann ◽  
U. Kassner ◽  
K. Norman ◽  
E. Steinhagen-Thiessen ◽  
I. Demuth ◽  
...  

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