Closure method for thick pancreas stump after distal pancreatectomy: soft coagulation and polyglycolic acid felt with fibrin glue

2015 ◽  
Vol 400 (7) ◽  
pp. 843-848 ◽  
Author(s):  
Hirofumi Akita ◽  
Hidenori Takahashi ◽  
Kunihito Gotoh ◽  
Shogo Kobayashi ◽  
Keijiro Sugimura ◽  
...  
Keyword(s):  
Distal Pancreatectomy ◽  
Fibrin Glue ◽  
Polyglycolic Acid ◽  
Soft Coagulation ◽  
Closure Method

Soft coagulation, polyglycolic acid felt, and fibrin glue for prevention of pancreatic fistula after distal pancreatectomy

Surgery Today ◽  
2011 ◽  
Vol 41 (9) ◽  
pp. 1224-1227 ◽  
Author(s):  
Toru Ikegami ◽  
Takashi Maeda ◽  
Hiroto Kayashima ◽  
Eiji Oki ◽  
Tomoharu Yoshizumi ◽  
...  
Keyword(s):  
Pancreatic Fistula ◽  
Distal Pancreatectomy ◽  
Fibrin Glue ◽  
Polyglycolic Acid ◽  
Soft Coagulation

scholarly journals Wrapping the pancreas with a polyglycolic acid sheet before stapling reduces the risk of fluid collection on the pancreatic stump after distal pancreatectomy

2021 ◽  
Author(s):  
Ji Su Kim ◽  
Seoung Yoon Rho ◽  
Dong Min Shin ◽  
Munseok Choi ◽  
Chang Moo Kang ◽  
...  
Keyword(s):  
Pancreatic Fistula ◽  
Distal Pancreatectomy ◽  
Fluid Collection ◽  
International Study ◽  
Polyglycolic Acid ◽  
Previous Method ◽  
Tertiary Referral ◽  
Tertiary Referral Hospital ◽  
Pancreatic Stump ◽  
Resection Line

Abstract Background Postoperative pancreatic fistula (POPF) and postoperative fluid collection (POFC) are common complications after distal pancreatectomy (DP). The previous method of reducing the risk of POPF was the application of a polyglycolic acid (PGA) sheet to the pancreatic stump after cutting the pancreas with a stapler (After-stapling); the new method involves wrapping the pancreatic resection line with a PGA sheet before stapling (Before-stapling). The study aimed to compare the incidence of POPF and POFC between two methods. Methods Data of patients who underwent open or laparoscopic DPs by a single surgeon from October 2010 to February 2020 in a tertiary referral hospital were retrospectively analyzed. POPF was defined according to the updated International Study Group of Pancreatic Fistula criteria. POFC was measured by postoperative computed tomography (CT). Results Altogether, 182 patients were enrolled (After-stapling group, n = 138; Before-stapling group, n = 44). Clinicopathologic and intraoperative findings between the two groups were similar. Clinically relevant POPF rates were similar between both groups (4.3% vs. 4.5%, p = 0.989). POFC was significantly lesser in the Before-stapling group on postoperative day 7 (p < 0.001). Conclusions Wrapping the pancreas with PGA sheet before stapling was a simple and effective way to reduce POFC.

scholarly journals Feasibility of a modified search, coagulation, and clipping method with and without the use of polyglycolic acid sheets and fibrin glue for preventing delayed bleeding after gastric endoscopic submucosal dissection

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Satoshi Abiko ◽  
Soichiro Oda ◽  
Akimitsu Meno ◽  
Akane Shido ◽  
Sonoe Yoshida ◽  
...  
Keyword(s):  
High Risk ◽  
Endoscopic Submucosal Dissection ◽  
Median Time ◽  
Fibrin Glue ◽  
Polyglycolic Acid ◽  
Low Risk ◽  
R0 Resection ◽  
Antithrombotic Agents ◽  
Delayed Bleeding ◽  
Submucosal Dissection

Abstract Background Methods have been developed for preventing delayed bleeding (DB) after gastric endoscopic submucosal dissection (GESD). However, none of the methods can completely prevent DB. We hypothesized that DB could be prevented by a modified search, coagulation, and clipping (MSCC) method for patients at low risk for DB and by combining the use of polyglycolic acid sheets and fibrin glue with the MSCC method (PMSCC method) for patients at high risk for DB (antibleeding [ABI] strategy). This study assessed the technical feasibility of this novel strategy. Method We investigated 123 lesions in 121 consecutive patients who underwent GESD in Kushiro Rosai Hospital between April 2018 and January 2020. The decision for continuation or cessation of antithrombotic agents was based on the Guidelines for Gastroenterological Endoscopy in Patients Undergoing Antithrombotic Treatment. Results Oral antithrombotic agents were administered to 28 patients (22.8%). The en bloc R0 resection rate was 98.4%. The MSCC method and the PMSCC method for preventing DB were performed in 114 and 9 lesions, respectively. The median time of the MSCC method was 16 min, and the median speed (the resection area divided by the time of method used) was 3.6 cm2/10 min. The median time of the PMSCC method was 59 min, and the median speed was 1.3 cm2/10 min. The only delayed procedural adverse event was DB in 1 (0.8%) of the 123 lesions. Conclusions The ABI strategy is feasible for preventing DB both in patients at low risk and in those at high risk for DB after GESD, whereas the PMSCC method may be necessary for reduction of time.

scholarly journals Nonsuture dural repair using polyglycolic acid mesh and fibrin glue: clinical application to spinal surgery

2006 ◽  
Vol 65 (2) ◽  
pp. 136-142 ◽  
Author(s):  
Kazutoshi Hida ◽  
Satoshi Yamaguchi ◽  
Toshitaka Seki ◽  
Shunsuke Yano ◽  
Minoru Akino ◽  
...  
Keyword(s):  
Fibrin Glue ◽  
Clinical Application ◽  
Spinal Surgery ◽  
Polyglycolic Acid ◽  
Dural Repair ◽  
Polyglycolic Acid Mesh

scholarly journals Fibrin adhesive and the vaginal vault synthesis on female rabbits abdominal hysterectomies

2009 ◽  
Vol 24 (1) ◽  
pp. 30-35 ◽  
Author(s):  
Ari Gonçalves Lima ◽  
Murched Omar Taha ◽  
Henri Chaplin Rivoire ◽  
Anna Tereza Negrini Fagundes ◽  
Djalma José Fagundes
Keyword(s):  
Fibrin Glue ◽  
Granulation Tissue ◽  
Fibrous Tissue ◽  
Rabbit Model ◽  
Abdominal Hysterectomy ◽  
Polyglycolic Acid ◽  
Vaginal Vault ◽  
Fisher Test ◽  
Burst Test ◽  
Significant Difference

PURPOSE: To investigate the effectiveness of fibrin glue in comparison with polyglycolic acid suture to promote the closure of rabbit's vaginal vault, after abdominal hysterectomy. METHODS: Twenty female, adults, New Zealand rabbits, were submitted to abdominal hysterectomy and randomly distributed to polyglycolic acid suture (G-PA / n=10) or fibrin glue closure of vaginal vault (G-FG / n=10). Radiograph study allowed identifying vault vaginal suture disrupter or fistulas to urinary bladder or rectum. Videovaginoscopy study allowed identifying the presence of cellulites, abscess formation, tissue granulation or granuloma. Vaginal cuff burst test allowed to identify by the escape of air bubbles and rupture pression record. Histological sections stained with Picrosirius red allowed the measure of fibrous tissue healing. RESULTS: The videovaginoscopy identified a significant difference (Fisher Test p<0.3142) of granulation tissue in the animals of G-PA (40%) in comparison with the G-FG (20%). The gross inspection showed the same relation in the granulation tissue occurrence (Fisher test p< 0.1749) with G-PA (50%) and G-FB (20%). The visceral adhesion to the vaginal vault wound was statistical significant (Fisher test p< 0.1749) with G-PA (50%) and G-FG (20%). The pressure of rupture (mm Hg) of the burst test was similar (p<0.0421) in the animals of G-PA (61.5±19.3) and G-FG (72.5±21.9). The collagen matrix of vault wound healing was similar (p< 0.0231) between the G-PA (31.63±15) and the G-FG (23.2±13.2). CONCLUSION: The vaginal vault closure using the fibrin glue is a safe and reliable procedure after abdominal hysterectomy in female rabbit model.

Use of fibrin glue sealant with polyglycolic acid sheets to prevent pancreatic fistula formation after laparoscopic-assisted gastrectomy

Surgery Today ◽  
2012 ◽  
Vol 43 (5) ◽  
pp. 527-533 ◽  
Author(s):  
Yuichiro Hiura ◽  
Shuji Takiguchi ◽  
Kazuyoshi Yamamoto ◽  
Yukinori Kurokawa ◽  
Makoto Yamasaki ◽  
...  
Keyword(s):  
Pancreatic Fistula ◽  
Fibrin Glue ◽  
Polyglycolic Acid ◽  
Fistula Formation ◽  
Fibrin Glue Sealant ◽  
Laparoscopic Assisted

scholarly journals Application of polyglycolic acid sheet and fibrin glue spray for partial glossectomy: Comparison with artificial dermis

2011 ◽  
Vol 57 (7) ◽  
pp. 394-400 ◽  
Author(s):  
Junichiro TAKEUCHI ◽  
Masahiro UMEDA ◽  
Maho MURATA ◽  
Yasumasa KAKEI ◽  
Akira KIMOTO ◽  
...  
Keyword(s):  
Fibrin Glue ◽  
Polyglycolic Acid ◽  
Polyglycolic Acid Sheet ◽  
Artificial Dermis ◽  
Partial Glossectomy

scholarly journals Endoscopic closure of an anastomo-cutaneous fistula: Filling and shielding using polyglycolic acid sheets and fibrin glue with easily deliverable technique

2018 ◽  
Vol 06 (08) ◽  
pp. E994-E997 ◽  
Author(s):  
Hideaki Kawabata ◽  
Yuji Okazaki ◽  
Naonori Inoue ◽  
Yukino Kawakatsu ◽  
Misuzu Hitomi ◽  
...  
Keyword(s):  
Pancreatic Cancer ◽  
Fibrin Glue ◽  
Polyglycolic Acid ◽  
Invasive Treatment ◽  
Cutaneous Fistula ◽  
Endoscopic Closure

Abstract Background and study aims Recently, endoscopic closure of gastrointestinal fistulas using polyglycolic acid (PGA) sheets with fibrin glue (FG) has been attempted. A 70-year-old woman who had undergone pancreaticoduodenectomy for pancreatic cancer suffered from a refractory anastomo-cutaneous fistula at the site of gastro-jejunostomy. We attempted endoscopic closure with filling and shielding using PGA sheets and FG. After introducing a guidewire into the fistula, a small piece of PGA sheet was skewered onto the guidewire and then pushed using a tapered catheter over the guidewire and delivered into the fistula. A total of 10 sheets were delivered via the same procedure. Next, the mucosa around the fistula was ablated, and the orifice of the fistula along with the surrounding mucosa was shielded with a piece of PGA sheet fixed with hemoclips and FG. After this procedure, the leakage disappeared and the fistula was undetectable on contrast radiograms. Endoscopic closure of anastomo-cutaneous fistula with filling and shielding using PGA sheets and FG is an effective, safe, low-invasive treatment, and the filling technique using a guidewire ensures a safe, smooth procedure.

Sign in / Sign up

Export Citation Format

Share Document