Perioperative management of endocrine insufficiency after total pancreatectomy for neoplasia

2017 ◽  
Vol 402 (6) ◽  
pp. 873-883 ◽  
Author(s):  
Ajay V. Maker ◽  
◽  
Raashid Sheikh ◽  
Vinita Bhagia
Keyword(s):  
Perioperative Management ◽  
Total Pancreatectomy ◽  
Endocrine Insufficiency

scholarly journals Retrospective Evaluation of the Perioperative Management of Patients Undergoing Total Pancreatectomy With Islet Autotransplantation

Pancreas ◽  
2019 ◽  
Vol 48 (2) ◽  
pp. 228-232
Author(s):  
Julie R. McSwain ◽  
Madeline Nykamp ◽  
Bethany J. Wolf ◽  
Jeffrey D. McMurray ◽  
Christopher A. Skorke ◽  
...  
Keyword(s):  
Perioperative Management ◽  
Total Pancreatectomy ◽  
Retrospective Evaluation ◽  
Islet Autotransplantation

scholarly journals Total pancreatectomy and salvage completion pancreatectomy-early and late outcomes without Islet cell auto-transplantation

2020 ◽  
Vol 9 (3) ◽  
pp. 154-160
Author(s):  
Dhiresh Kumar Maharjan ◽  
Prabin Bikram Thapa
Keyword(s):  
Quality Of Life ◽  
Islet Cell ◽  
Total Pancreatectomy ◽  
Matched Pairs ◽  
Whipple Operation ◽  
Life Index ◽  
Endocrine Insufficiency ◽  
Quality Of Life Index ◽  
Completion Pancreatectomy

Background: Total pancreatectomy was abandoned for decades because of high peri and post-operative morbidity and mortality. However, with better peri-operative outcome and post-operative management of exocrine and endocrine insufficiency, the hesitancy to perform total pancreatectomy has been disappearing.  Objectives: This study aims to study exocrinal and endocrinal effects of total pancreatectomy without Islet cell auto-transplantation and compare quality of life index among total pancreatectomy with Whipple patients. Methodology: This is a prospectively conducted matched-pairs study. Group A underwent total or completion pancreatectomy after non-salvageable complications of Whipple operation. A matched-pairs analysis of quality of life index of these patients by using SF-36 questionnaire were compared with Group B who underwent Whipple operation during the same period of time, according to age, gender and pre-operative diagnosis.  Results: In four years (from February 2016 to February 2020), 160 patients underwent Whipple operation. The mean age of the patients was 59.9 +/-14.3 years. A total of nine patients underwent total pancreatectomy, among which two had per-operative decision of total pancreatectomy and seven had completion pancreatectomy. Median post-operative hospital stay was 11 days with two mortalities. Median follow-up of 12 months and quality of life index of total pancreatectomy patients were comparable to Whipple patients, although a few single quality of life items were reduced.  Conclusion: Exocrinal pancreatic supplements and long acting insulin have augmented control of diabetes despite of not using Islet cell auto-transplantation. Quality of life index of total pancreatectomy patients were comparable to that of Whipple patients. Hence, this study signifies the   importance of completion pancreatectomy following non-salvageable complications after Whipple operation in order to save life.

scholarly journals Total Pancreatectomy with Autologous Islet Cell Transplantation—The Current Indications

2021 ◽  
Vol 10 (12) ◽  
pp. 2723
Author(s):  
Beata Jabłońska ◽  
Sławomir Mrowiec
Keyword(s):  
Total Pancreatectomy ◽  
Long Term Results ◽  
Pancreatic Tumors ◽  
Neuroendocrine Neoplasms ◽  
Islet Cell Transplantation ◽  
Pancreatic Stump ◽  
Primary Indication ◽  
Autologous Islet Transplantation ◽  
Endocrine Insufficiency

Total pancreatectomy is a major complex surgical procedure involving removal of the whole pancreatic parenchyma and duodenum. It leads to lifelong pancreatic exocrine and endocrine insufficiency. The control of surgery-induced diabetes (type 3) requires insulin therapy. Total pancreatectomy with autologous islet transplantation (TPAIT) is performed in order to prevent postoperative diabetes and its serious complications. It is very important whether it is safe and beneficial for patients in terms of postoperative morbidity and mortality, and long-term results including quality of life. Small duct painful chronic pancreatitis (CP) is a primary indication for TPAIT, but currently the indications for this procedure have been extended. They also include hereditary/genetic pancreatitis (HGP), as well as less frequent indications such as benign/borderline pancreatic tumors (intraductal papillary neoplasms, neuroendocrine neoplasms) and “high-risk pancreatic stump”. The use of TPAIT in malignant pancreatic and peripancreatic neoplasms has been reported in the worldwide literature but currently is not a standard but rather a controversial management in these patients. In this review, history, technique, indications, and contraindications, as well as short-term and long-term results of TPAIT, including pediatric patients, are described.

A Perioperative Management to Reduce Pulmonary Embolism after Meningioma Resection

2012 ◽  
Vol 73 (S 03) ◽  
Author(s):  
C. Eisenring ◽  
J. Sarnthein ◽  
D. Sabanés Bové ◽  
L. Held ◽  
N. Krayenbühl
Keyword(s):  
Pulmonary Embolism ◽  
Perioperative Management

A Case of Catecholamine-Secreting Glomus Jugulare Tumor: Treatment Strategy and Perioperative Management

Skull Base ◽  
2008 ◽  
Vol 18 (S 01) ◽  
Author(s):  
Hiroaki Motegi ◽  
Shunsuke Terasaka ◽  
Shigeru Yamaguchi ◽  
Hiroyuki Kobayashi ◽  
Katsuyuki Asaoka ◽  
...  
Keyword(s):  
Treatment Strategy ◽  
Perioperative Management ◽  
Tumor Treatment ◽  
Glomus Jugulare Tumor ◽  
Glomus Jugulare

119-OR: Total Pancreatectomy with Islet Autotransplantation in Diabetic and Prediabetic Patients with Intractable Chronic Pancreatitis

Diabetes ◽  
2020 ◽  
Vol 69 (Supplement 1) ◽  
pp. 119-OR
Author(s):  
PIOTR J. BACHUL ◽  
PETER BOREK ◽  
ROI ANTEBY ◽  
LINDSAY BASTO ◽  
LAURENCIA PEREA ◽  
...  
Keyword(s):  
Chronic Pancreatitis ◽  
Total Pancreatectomy ◽  
Islet Autotransplantation
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