Chemokine receptor CCR6 expression level and aggressiveness of prostate cancer

2008 ◽  
Vol 134 (11) ◽  
pp. 1181-1189 ◽  
Author(s):  
Pirus Ghadjar ◽  
Christoph Loddenkemper ◽  
Sarah Ellen Coupland ◽  
Andrea Stroux ◽  
Michel Noutsias ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Chemokine Receptor ◽  
Expression Level

Design, syntheses, and characterization of piperazine based chemokine receptor CCR5 antagonists as anti prostate cancer agents

2014 ◽  
Vol 24 (10) ◽  
pp. 2319-2323 ◽  
Author(s):  
Christopher K. Arnatt ◽  
Joanna L. Adams ◽  
Zhu Zhang ◽  
Kendra M. Haney ◽  
Guo Li ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Chemokine Receptor ◽  
Chemokine Receptor Ccr5 ◽  
Ccr5 Antagonists ◽  
Receptor Ccr5

scholarly journals The expression level of lysophosphatidylcholine acyltransferase 1 (LPCAT1) correlates to the progression of prostate cancer

2012 ◽  
Vol 92 (1) ◽  
pp. 105-110 ◽  
Author(s):  
Xinchun Zhou ◽  
Thomas J. Lawrence ◽  
Zhi He ◽  
Charles R. Pound ◽  
Jinghe Mao ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Expression Level

scholarly journals Androgens Modulate Expression of Transcription Intermediary Factor 2, an Androgen Receptor Coactivator whose Expression Level Correlates with Early Biochemical Recurrence in Prostate Cancer

2006 ◽  
Vol 66 (21) ◽  
pp. 10594-10602 ◽  
Author(s):  
Irina U. Agoulnik ◽  
Ajula Vaid ◽  
Manjula Nakka ◽  
Misty Alvarado ◽  
William E. Bingman ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Androgen Receptor ◽  
Biochemical Recurrence ◽  
Expression Level

scholarly journals MiR-455-5p Suppresses the Progression of Prostate Cancer by Targeting CCR5

2019 ◽  
Vol 2019 ◽  
pp. 1-8 ◽  
Author(s):  
Qianwei Xing ◽  
Huyang Xie ◽  
Bingye Zhu ◽  
Zhiwei Sun ◽  
Yeqing Huang
Keyword(s):  
Prostate Cancer ◽  
Chemokine Receptor ◽  
Poor Prognosis ◽  
Therapeutic Strategy ◽  
Caspase 3 ◽  
Cellular Proliferation ◽  
Cancer Center ◽  
Human Prostate Cancer ◽  
Inhibit Tumor Growth ◽  
Functional Assays

Accumulated evidence indicates that miR-455-5p functions as tumor suppressor in the progression of various cancers. However, the mechanism through which miR-455-5p influences the tumorigenesis of human prostate cancer (PCa) remains undetermined. In this study, reanalysis of data obtained from the Memorial Sloan Kettering Cancer Center showed that miR-455-5p can be used as biomarker for PCa diagnosis and predictor of poor prognosis. Functional assays indicated that miR-455-5p overexpression could suppress cellular proliferation, inhibit tumor growth, and trigger apoptosis by activating and cleaving caspase 3. We experimentally verified that miR-455-5p negatively regulated the C–C motif chemokine receptor 5 (CCR5). Overall, our data demonstrate that miR-455-5p suppressed PCa cellular proliferation and induced cell apoptosis by downregulating CCR5. Thus, miR-455-5p may be considered a new therapeutic strategy for PCa.

scholarly journals Chemokine receptor CXCR4 expression and prognosis in patients with metastatic prostate cancer

2008 ◽  
Vol 99 (3) ◽  
pp. 539-542 ◽  
Author(s):  
Takuya Akashi ◽  
Keiichi Koizumi ◽  
Koichi Tsuneyama ◽  
Ikuo Saiki ◽  
Yasuo Takano ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Chemokine Receptor ◽  
Metastatic Prostate Cancer ◽  
Cxcr4 Expression ◽  
Chemokine Receptor Cxcr4

MP-17.04: Chemokine receptor CXCR4 expression and prognosis in patients with metastatic prostate cancer

Urology ◽  
2007 ◽  
Vol 70 (3) ◽  
pp. 130-131
Author(s):  
T. Akashi ◽  
K. Koizumi ◽  
K. Tsuneyama ◽  
I. Saiki ◽  
Y. Takano ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Chemokine Receptor ◽  
Metastatic Prostate Cancer ◽  
Cxcr4 Expression ◽  
Chemokine Receptor Cxcr4

scholarly journals No Association between Common Chemokine and Chemokine Receptor Gene Variants and Prostate Cancer Risk

2008 ◽  
Vol 17 (12) ◽  
pp. 3615-3617 ◽  
Author(s):  
D. C. Petersen ◽  
G. Severi ◽  
H. N. Hoang ◽  
E. J.D. Padilla ◽  
M. C. Southey ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Cancer Risk ◽  
Chemokine Receptor ◽  
Receptor Gene ◽  
Prostate Cancer Risk ◽  
Gene Variants ◽  
Chemokine Receptor Gene

The Prognostic Significance of CXCL16 and Its Receptor C-X-C Chemokine Receptor 6 in Prostate Cancer

2015 ◽  
Vol 185 (10) ◽  
pp. 2722-2730 ◽  
Author(s):  
Elin Richardsen ◽  
Nora Ness ◽  
Christian Melbø-Jørgensen ◽  
Charles Johannesen ◽  
Thea Grindstad ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Chemokine Receptor ◽  
Prognostic Significance

The role of the chemokine receptor CXCR4 and its ligand CXCL12 in prostate cancer

2003 ◽  
Vol 2 (1) ◽  
pp. 163
Author(s):  
M. Arya ◽  
R. Tatoud ◽  
C. Megurk ◽  
E.P.N. O'Donoghue ◽  
H. Klocker ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Chemokine Receptor ◽  
Chemokine Receptor Cxcr4
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