Poly(lactic-co-glycolide) polymer constructs cross-linked with human BMP-6 and VEGF protein significantly enhance rat mandible defect repair

2015 ◽  
Vol 364 (1) ◽  
pp. 125-135 ◽  
Author(s):  
Anusuya Das ◽  
Brian A. Fishero ◽  
J. Jared Christophel ◽  
Ching-Ju Li ◽  
Nikita Kohli ◽  
...  
2003 ◽  
Vol 5 (1) ◽  
pp. 103-108 ◽  
Author(s):  
Oneida A. Arosarena ◽  
Arthur Falk ◽  
Leslie Malmgren ◽  
Linda Bookman ◽  
Matthew J. Allen ◽  
...  

2006 ◽  
Vol 72 (2) ◽  
pp. 195-199
Author(s):  
Andréa Thomaz Soccol ◽  
Silvio Bettega ◽  
Lúcia Noronha ◽  
Sheila Sass ◽  
Vanete T. Soccol ◽  
...  

Author(s):  
Yasushi P. Kato ◽  
Michael G. Dunn ◽  
Frederick H. Silver ◽  
Arthur J. Wasserman

Collagenous biomaterials have been used for growing cells in vitro as well as for augmentation and replacement of hard and soft tissues. The substratum used for culturing cells is implicated in the modulation of phenotypic cellular expression, cellular orientation and adhesion. Collagen may have a strong influence on these cellular parameters when used as a substrate in vitro. Clinically, collagen has many applications to wound healing including, skin and bone substitution, tendon, ligament, and nerve replacement. In this report we demonstrate two uses of collagen. First as a fiber to support fibroblast growth in vitro, and second as a demineralized bone/collagen sponge for radial bone defect repair in vivo.For the in vitro study, collagen fibers were prepared as described previously. Primary rat tendon fibroblasts (1° RTF) were isolated and cultured for 5 days on 1 X 15 mm sterile cover slips. Six to seven collagen fibers, were glued parallel to each other onto a circular cover slip (D=18mm) and the 1 X 15mm cover slip populated with 1° RTF was placed at the center perpendicular to the collagen fibers. Fibroblast migration from the 1 x 15mm cover slip onto and along the collagen fibers was measured daily using a phase contrast microscope (Olympus CK-2) with a calibrated eyepiece. Migratory rates for fibroblasts were determined from 36 fibers over 4 days.


2013 ◽  
Author(s):  
Aval Fereydoon Sargolzaei ◽  
Mohammad Reza Arab ◽  
Aval Forough Sargolzaei

2005 ◽  
Vol 8 (1) ◽  
pp. 23 ◽  
Author(s):  
Sanjay Kumar ◽  
Bharati Sinha

Chylopericardium after intrapericardial cardiac operations is extremely rare. We present an unusual case of postoperative chylopericardium with cardiac tamponade following atrial septal defect repair, and we comment on the clinical course and treatment.


Author(s):  
B. C. King ◽  
J. Hagan ◽  
R. Corroenne ◽  
A. A. Shamshirsaz ◽  
J. Espinoza ◽  
...  

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