Endogenous hydrophobic compounds affect the hydrophobic capacity of plants and influence the forest filter effect

2003 ◽  
Vol 17 (4) ◽  
pp. 249-251 ◽  
Author(s):  
H. Kylin ◽  
A. Hellstr�m
Keyword(s):  
Hydrophobic Compounds ◽  
Filter Effect ◽  
Forest Filter ◽  
Forest Filter Effect

Forest Filter Effect: Role of leaves in capturing/releasing air particulate matter and its associated PAHs

2013 ◽  
Vol 74 ◽  
pp. 378-384 ◽  
Author(s):  
Elisa Terzaghi ◽  
Edward Wild ◽  
Gabriele Zacchello ◽  
Bruno E.L. Cerabolini ◽  
Kevin C. Jones ◽  
...  
Keyword(s):  
Particulate Matter ◽  
Air Particulate Matter ◽  
Air Particulate ◽  
Filter Effect ◽  
Forest Filter ◽  
Forest Filter Effect

Are airborne organic pollutants subject to a ?forest filter effect??

2003 ◽  
Vol 17 (4) ◽  
pp. 244-248 ◽  
Author(s):  
F. Wegmann ◽  
M. Scheringer ◽  
M. M�ller ◽  
K. Hungerb�hler
Keyword(s):  
Organic Pollutants ◽  
Filter Effect ◽  
Forest Filter ◽  
Forest Filter Effect

scholarly journals Is there a ?forest filter effect? for organic pollutants?

2003 ◽  
Vol 17 (4) ◽  
pp. 231-234 ◽  
Author(s):  
R. L. Maddalena ◽  
T. E. McKone ◽  
W. J. Riley
Keyword(s):  
Organic Pollutants ◽  
Filter Effect ◽  
Forest Filter ◽  
Forest Filter Effect

Nanoemulsions Loaded with Amphotericin B: Development, Characterization and Leishmanicidal Activity

2019 ◽  
Vol 25 (14) ◽  
pp. 1616-1622 ◽  
Author(s):  
Gabriela Muniz Félix Araújo ◽  
Gabriela Muniz Félix Araújo ◽  
Alana Rafaela Albuquerque Barros ◽  
Alana Rafaela Albuquerque Barros ◽  
João Augusto Oshiro-Junior ◽  
...  
Keyword(s):  
Amphotericin B ◽  
Average Diameter ◽  
Isopropyl Myristate ◽  
Neglected Diseases ◽  
Clinical Form ◽  
Hydrophobic Compounds ◽  
Internal Phase ◽  
Oil In Water ◽  
Spherical Structures ◽  
Lipid Formulations

Leishmaniasis is one of the most neglected diseases in the world. Its most severe clinical form, called visceral, if left untreated, can be fatal. Conventional therapy is based on the use of pentavalent antimonials and includes amphotericin B (AmB) as a second-choice drug. The micellar formulation of AmB, although effective, is associated with acute and chronic toxicity. Commercially-available lipid formulations emerged to overcome such drawbacks, but their high cost limits their widespread use. Drug delivery systems such as nanoemulsions (NE) have proven ability to solubilize hydrophobic compounds, improve absorption and bioavailability, increase efficacy and reduce toxicity of encapsulated drugs. NE become even more attractive because they are inexpensive and easy to prepare. The aim of this work was to incorporate AmB in NE prepared by sonicating a mixture of surfactants, Kolliphor® HS15 (KHS15) and Brij® 52, and an oil, isopropyl myristate. NE exhibited neutral pH, conductivity values consistent with oil in water systems, spherical structures with negative Zeta potential value, monomodal size distribution and average diameter of drug-containing droplets ranging from 33 to 132 nm. AmB did not modify the thermal behavior of the system, likely due to its dispersion in the internal phase. Statistically similar antileishmanial activity of AmB-loaded NE to that of AmB micellar formulation suggests further exploring them in terms of toxicity and effectiveness against amastigotes, with the aim of offering an alternative to treat visceral leishmaniasis.

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