Dynamics of mitochondrial distribution during development and asymmetric division of rice zygotes

2021 ◽  
Author(s):  
Hanifah Aini ◽  
Yoshikatsu Sato ◽  
Kakishi Uno ◽  
Tetsuya Higashiyama ◽  
Takashi Okamoto
Keyword(s):  
Asymmetric Division ◽  
Mitochondrial Distribution

scholarly journals Fusion, fission, and transport control asymmetric inheritance of mitochondria and protein aggregates

2017 ◽  
Vol 216 (8) ◽  
pp. 2481-2498 ◽  
Author(s):  
Stefan Böckler ◽  
Xenia Chelius ◽  
Nadine Hock ◽  
Till Klecker ◽  
Madita Wolter ◽  
...  
Keyword(s):  
Protein Aggregates ◽  
Asymmetric Division ◽  
Cell Organelles ◽  
Mitochondrial Transport ◽  
Daughter Cells ◽  
Transport Control ◽  
Live Cell Microscopy ◽  
Mitochondrial Distribution ◽  
Cell Microscopy

Partitioning of cell organelles and cytoplasmic components determines the fate of daughter cells upon asymmetric division. We studied the role of mitochondria in this process using budding yeast as a model. Anterograde mitochondrial transport is mediated by the myosin motor, Myo2. A genetic screen revealed an unexpected interaction of MYO2 and genes required for mitochondrial fusion. Genetic analyses, live-cell microscopy, and simulations in silico showed that fused mitochondria become critical for inheritance and transport across the bud neck in myo2 mutants. Similarly, fused mitochondria are essential for retention in the mother when bud-directed transport is enforced. Inheritance of a less than critical mitochondrial quantity causes a severe decline of replicative life span of daughter cells. Myo2-dependent mitochondrial distribution also is critical for the capture of heat stress–induced cytosolic protein aggregates and their retention in the mother cell. Together, these data suggest that coordination of mitochondrial transport, fusion, and fission is critical for asymmetric division and rejuvenation of daughter cells.

scholarly journals Effects of dimethyl sulfoxide on asymmetric division and cytokinesis in mouse oocytes

2014 ◽  
Vol 14 (1) ◽  
pp. 28 ◽  
Author(s):  
Dongjie Zhou ◽  
Xinghui Shen ◽  
Yanli Gu ◽  
Na Zhang ◽  
Tong Li ◽  
...  
Keyword(s):  
Dimethyl Sulfoxide ◽  
Asymmetric Division ◽  
Mouse Oocytes

TSH attenuates fatty acid oxidation in hepatocytes by reducing the mitochondrial distribution of miR-449a/449b-5p/5194

2021 ◽  
Vol 530 ◽  
pp. 111280
Author(s):  
Jiaxuan Li ◽  
Danxia Kong ◽  
Xueying Gao ◽  
Zhenyu Tian ◽  
Xiaowei Wang ◽  
...  
Keyword(s):  
Fatty Acid ◽  
Fatty Acid Oxidation ◽  
Acid Oxidation ◽  
Mitochondrial Distribution
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