Early detection of liver failure after hepatectomy by indocyanine green elimination rate measured by pulse dye-densitometry

2006 ◽  
Vol 13 (6) ◽  
pp. 543-548 ◽  
Author(s):  
Hiroyuki Sugimoto ◽  
Osamu Okochi ◽  
Masashi Hirota ◽  
Naohito Kanazumi ◽  
Shuji Nomoto ◽  
...  
Keyword(s):  
Early Detection ◽  
Liver Failure ◽  
Indocyanine Green ◽  
Elimination Rate

Perioperative use of the LiMON method of indocyanine green elimination measurement for the prediction and early detection of post-hepatectomy liver failure

2009 ◽  
Vol 35 (9) ◽  
pp. 957-962 ◽  
Author(s):  
N. de Liguori Carino ◽  
D.A. O'Reilly ◽  
K. Dajani ◽  
P. Ghaneh ◽  
G.J. Poston ◽  
...  
Keyword(s):  
Early Detection ◽  
Liver Failure ◽  
Indocyanine Green

Role of Procalcitonin in Early Detection of Infections in Acute on Chronic Liver Failure in Liver Intensive Care

2016 ◽  
Vol 6 ◽  
pp. S7
Author(s):  
Swapnil Dhampalwar ◽  
Aamritangsu Borkakoty ◽  
Sunil Taneja ◽  
Ajay Duseja ◽  
Radha K. Dhiman ◽  
...  
Keyword(s):  
Intensive Care ◽  
Early Detection ◽  
Liver Failure ◽  
Chronic Liver ◽  
Chronic Liver Failure

scholarly journals Role of Indocyanine Green in Predicting Post-Transarterial Chemoembolization Liver Failure in Hepatocellular Carcinoma

2018 ◽  
Vol 8 (1) ◽  
pp. 28-34 ◽  
Author(s):  
Shalimar ◽  
Sushil Jain ◽  
Shivanand R. Gamanagatti ◽  
Saurabh Kedia ◽  
Bhaskar Thakur ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Liver Failure ◽  
Indocyanine Green ◽  
Transarterial Chemoembolization

Postabsorption antidotal effects of N-acetylcysteine on acetaminophen-induced hepatotoxicity in the mouse

1985 ◽  
Vol 63 (5) ◽  
pp. 431-437 ◽  
Author(s):  
L. W. Whitehouse ◽  
L. T. Wong ◽  
C. J. Paul ◽  
A. Pakuts ◽  
G. Solomonraj
Keyword(s):  
Indocyanine Green ◽  
Urinary Excretion ◽  
Rate Constants ◽  
Degradation Products ◽  
Elimination Rate ◽  
Hepatic Circulation ◽  
General Increase ◽  
Hepatic Congestion ◽  
Metabolic Consequence

Male Swiss Webster mice, treated with N-acetylcysteine (NAC, 500 mg/kg po) 1 h following acetaminophen (NAPA, 350 mg/kg po) administration, had control levels of transaminases indicating that NAC protects against NAPA-induced hepatotoxicity by postabsorption antidotal mechanism(s). Hepatic congestion induced by NAPA was reduced by NAC. Significantly higher elimination rate constants (K) for indocyanine green (500 μg/kg, iv) in mice treated with NAPA and NAC (K = 0.676 ± 0.062) than in animals receiving NAPA alone (0.341 ± 0.105) suggested NAC improved or preserved the hepatic circulation of the compromised liver. This NAC-induced improvement and (or) preservation of hepatic circulation was reflected in biliary and urinary excretion of acetaminophen and its metabolites by a general increase in elimination during the first 6 h (70.2 ± 2.6 vs. 32.6 ± 7.1%), and in the repletion of glutathione (GSH) in the liver by a return to control levels more quickly (3 vs. >5 h) following depletion by NAPA. The metabolic consequence of the postabsorption antidotal effect of NAC in the compromised liver was a preferential excretion of sulphydryl-derived metabolites in the 1–4 h bile (GSH conjugate 11.30 ± 1.25 vs. 7.25 ± 0.39%) which was subsequently observed in the urine by preferential excretion of glutathione degradation products.

Indocyanine Green as a Predictor of Development of Post Transarterial Chemoembolisation Liver Failure

2014 ◽  
Vol 4 ◽  
pp. S57-S58
Author(s):  
Subrat K. Acharya ◽  
Sushil Jain ◽  
S. Shalimar ◽  
Baibaswat Nayak ◽  
Devesh Prakash ◽  
...  
Keyword(s):  
Liver Failure ◽  
Indocyanine Green ◽  
Transarterial Chemoembolisation
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