Endoscopic transgastric pure NOTES cholecystectomy with naso-gallbladder drainage tube placement and injection of a hyaluronic acid mixture (with Video)

2010 ◽  
Vol 18 (1) ◽  
pp. 106-111 ◽  
Author(s):  
Hiroyuki Isayama ◽  
Hirofumi Kogure ◽  
Kazuhiko Koike
Keyword(s):  
Hyaluronic Acid ◽  
Drainage Tube ◽  
Tube Placement ◽  
Acid Mixture ◽  
Gallbladder Drainage

The ProSeal Laryngeal Mask Airway

2000 ◽  
Vol 93 (1) ◽  
pp. 104-109 ◽  
Author(s):  
Joseph Brimacombe ◽  
Christian Keller
Keyword(s):  
Laryngeal Mask Airway ◽  
Gastric Tube ◽  
Proseal Laryngeal Mask Airway ◽  
Laryngeal Mask ◽  
Drainage Tube ◽  
Tube Placement ◽  
Success Rates ◽  
Sealing Pressure ◽  
Effective Seal ◽  
First Time

Background The ProSeal laryngeal mask airway (PLMA) is a new laryngeal mask device with a modified cuff to improve seal and a drainage tube to provide a channel for regurgitated fluid and gastric tube placement. In the present randomized, crossover study, the authors tested the hypothesis that ease of insertion, airway sealing pressure, and fiberoptic position differ between the PLMA and the standard laryngeal mask airway (LMA). For the PLMA, we also assess ease of gastric tube placement and the efficacy of an introducer tool. Methods Sixty paralyzed, anesthetized adult patients were studied. Both devices (only size 4) were inserted into each patient in random order. Airway sealing pressure and fiberoptic position were determined during cuff inflation from 0 to 40 ml in 10-ml increments. Gastric tube insertion was attempted with the PLMA if there was no gas leak from the drainage tube. In 60 additional patients, ease of insertion for the PLMA was compared with and without an introducer. Results First-time success rates were higher (60 of 60 vs. 52 of 60; P = 0.003) and the effective airway time shorter (9 +/- 3 s vs20 +/- 18 s; P < 0.0001) for the LMA. There were no failed uses of either device within three attempts. Airway sealing pressure was 8-11 cm H2O higher for the PLMA at all cuff volumes (P < 0.00001) and was higher in females for both devices. Fiberoptic position was better with the LMA at all cuff volumes (P < 0.00001), but vocal cord visibility was similar (LMA, 59 of 60; PLMA, 56 of 60). For the PLMA, gastric tube placement was successful in 58 of 58 patients and took 9 +/- 5 s. First-time success rates were higher (59 of 60 vs53/60; P = 0.03) and the effective airway time shorter (15 +/- 13 s vs 23 +/- 18 s; P = 0.008) with the introducer. Conclusion The PLMA is capable of achieving a more effective seal than the LMA and facilitates gastric tube placement, but it is more difficult to insert unless an introducer tool is used. When correctly positioned, the PLMA isolates the glottis from the upper esophagus with possible implications for airway protection.

Diagnosis and Patients Management of Gallbladder Disease by Bile Cytology Using Endoscopic Transpapillary Gallbladder Drainage Tube

2004 ◽  
Vol 59 (5) ◽  
pp. P182
Author(s):  
Takao Itoi ◽  
Kazuto Nakamura ◽  
Atsushi Sofuni ◽  
Fumihide Itokawa ◽  
Kazuhiro Kakimi ◽  
...  
Keyword(s):  
Gallbladder Disease ◽  
Drainage Tube ◽  
Gallbladder Drainage ◽  
Bile Cytology

scholarly journals Efficacy of the Mineral Oil and Hyaluronic Acid Mixture Eye Drops in Murine Dry Eye

2015 ◽  
Vol 29 (2) ◽  
pp. 131 ◽  
Author(s):  
Jung Han Choi ◽  
Jung Han Kim ◽  
Zhengri Li ◽  
Han Jin Oh ◽  
Kyu Youn Ahn ◽  
...  
Keyword(s):  
Hyaluronic Acid ◽  
Dry Eye ◽  
Mineral Oil ◽  
Acid Mixture ◽  
Eye Drops

scholarly journals The efficacy and safety of indocyanine green-hyaluronic acid mixture (LuminoMark™) for localization in patients with non-palpable breast lesions: a multi-center open-label parallel phase-2 clinical trial

BMC Surgery ◽  
2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Isaac Kim ◽  
Hee Jun Choi ◽  
Jai Min Ryu ◽  
Se Kyung Lee ◽  
Jong Han Yu ◽  
...  
Keyword(s):  
Clinical Trial ◽  
Hyaluronic Acid ◽  
Test Group ◽  
Acid Mixture ◽  
Control Group ◽  
Breast Lesions ◽  
Efficacy And Safety ◽  
Group 2 ◽  
Palpable Breast ◽  
Group 1

Abstract Background Increasing rates of breast cancer screening have been associated with an increasing frequency of non-palpable breast lesions detection. Preoperative breast lesion localization is essential for optimizing excision accuracy. This study aimed to evaluate the efficacy and safety of indocyanine green (ICG) hyaluronic acid injection as a novel mixture for localization. Methods We performed a prospective clinical trial with female patients who underwent surgery for non-palpable breast lesions. All patients were sequentially assigned to the control group (localization with activated charcoal), Test Group 1 (ICG-hyaluronic acid mixture 0.1 mL), or Test Group 2 (ICG-hyaluronic acid mixture 0.2 mL) by 1:1:1 ratio. Results A total of 44 patients were eligible for this study (Control Group = 14, Test Group 1 = 15, Test Group 2 = 15 patients). Fibroadenoma (n = 17, 38.6%) accounted for the largest proportion of diagnoses, and five patients (11.4%) were diagnosed with malignancies. There were no statistically significant differences in baseline characteristics among the three groups. The marking rate was over 86% in all groups, with no significant intergroup differences. Skin pigmentation was only observed in the control group. The mean accuracy of resection (the greatest diameter of the excised specimen divided by the greatest diameter of the preoperative lesion as observed using ultrasonography, with values closer to 1 reflecting a higher accuracy) was 3.7 in the control group, 2.2 in Test Group 1, and 2.1 in Test Group 2 (p = 0.037 between Controls and Test Group 1, p = 0.744 between Test Group 1 and Test Group 2, and p = 0.026 between Controls and Test Group 2). Conclusion ICG-hyaluronic acid injection is a novel method that was shown to accurately localize non-palpable breast lesions and was associated with no skin pigmentation. Further research is required to apply this method to malignant breast lesions. Trial registration “A Multicenter Open-label, Parallel, Phase 2 Clinical Trial to Evaluate the Efficacy and Safety of LuminoMark™ Inj. (Conc. for Fluorescence) Localization in Patients with Non-palpable Breast Lesions” was prospectively registered as a trial (ClinicalTrials. gov Identifier: NCT03743259, date of registration: May 29, 2018, https://clinicaltrials.gov/ct2/show/NCT03743259)

Melatonin and Hyaluronic Acid Mixture as a Possible Therapeutic Agent in Dental Medicine

2018 ◽  
Vol 69 (8) ◽  
pp. 1996-1999 ◽  
Author(s):  
Corina Marilena Cristache ◽  
Eugenia Eftimie Totu ◽  
Daniel Petre ◽  
Roxana Buga ◽  
Gheorghe Cristache ◽  
...  
Keyword(s):  
Hyaluronic Acid ◽  
Therapeutic Agent ◽  
Correlation Coefficients ◽  
Acid Mixture ◽  
Analysis Method ◽  
Simple Analysis ◽  
Efficient Procedure ◽  
First Derivative ◽  
Regression Correlation

The present work reports an efficient procedure for a simultaneous determination of melatonin (MEL) and hyaluronic acid (HA) mixture applying first derivative UV-Vis spectrophotometry. At selected wavelength (205 nm), the linearity range for each component of the mixture was established. The linear regression correlation coefficients for the direct UV-Vis spectra (RHA2 = 0.9627) and their first derivate (RHA2 = 0.9986) put in evidence a better fit for the derivative procedure. Through such simple analysis method, it was possible to emphasize that each component of MEL-HA mixture preserves its identity and characteristic properties. Consequently, the association of MEL and HA biomolecules could be used for obtaining a complex therapeutic agent with extensive applications in dental medicine.

scholarly journals Comparison of Medpor Coated Tear Drainage Tube versus Silicon Tear Drainage Tube in Conjunctivodacryocystorhinostomy: Problems and Solutions

2014 ◽  
Vol 2014 ◽  
pp. 1-7 ◽  
Author(s):  
Selam Yekta Sendul ◽  
Halil Huseyin Cagatay ◽  
Burcu Dirim ◽  
Mehmet Demir ◽  
Ali Atakhan Yıldız ◽  
...  
Keyword(s):  
Drainage Tube ◽  
Tube Placement ◽  
Tube Obstruction ◽  
Tube Extrusion ◽  
Initial Surgery ◽  
Problems And Solutions ◽  
Group 2 ◽  
Retrospective Comparative Study ◽  
Tube Versus ◽  
Tube Malposition

Purpose.This study aims at comparing two different types of drainage tubes in conjunctivodacryocystorhinostomy, which are used for upper lacrimal system obstruction or damage, with respect to their respective postoperative problems and solutions.Methods.Nineteen eyes of 17 patients who underwent conjunctivodacryocystorhinostomy (CDCR) or conjunctivorhinostomy (CR) surgery with a Medpor coated tear drainage tube or silicon tube placement between October, 2010, and February, 2014, were included in this retrospective comparative study.Results.In the initial surgery, Medpor coated tear drainage tubes were used in 11 eyes by CDCR, whereas silicon tear drainage tubes were implanted into 2 eyes by CR and 6 eyes by CDCR. In group 1, proximal and distal obstructions developed postoperatively in 4 eyes, while 1 eye showed tube malposition and 3 eyes developed luminal obstruction by debris 3 times. In group 2, tube extrusion developed in 4 eyes, whereas tube malposition developed in 6 eyes and luminal obstruction by debris developed in 6 eyes at different times, for a total of 20 times.Conclusions.In our study, the most significant complication we observed in the use of silicon tear drainage tubes was tube extrusion,whereas the leading complication related to the use of Medpor coated tear drainage tubes was tube obstruction.

scholarly journals Thoracoscopic Surgery Without Drainage Tube Placement for Peripheral Lung Nodules

2020 ◽  
Vol 109 (3) ◽  
pp. 887-893 ◽  
Author(s):  
Hsien-Chi Liao ◽  
Shun-Mao Yang ◽  
Ming-Hui Hung ◽  
Ya-Jung Cheng ◽  
Hsao-Hsun Hsu ◽  
...  
Keyword(s):  
Thoracoscopic Surgery ◽  
Drainage Tube ◽  
Tube Placement ◽  
Lung Nodules ◽  
Peripheral Lung

scholarly journals The Efficacy and Safety of Indocyanine green- hyaluronic acid mixture (LuminoMarkTM) for Localization in Patients with Non-palpable Breast Lesions: A Multi-center Open-label Parallel Phase-2 Clinical trial

2020 ◽  
Author(s):  
Isaac Kim ◽  
Hee Jun Choi ◽  
Jai Min Ryu ◽  
Se Kyung Lee ◽  
Jong Han Yu ◽  
...  
Keyword(s):  
Clinical Trial ◽  
Hyaluronic Acid ◽  
Breast Lesion ◽  
Ultrasound Image ◽  
Test Group ◽  
Acid Mixture ◽  
Control Group ◽  
Breast Lesions ◽  
Efficacy And Safety ◽  
Palpable Breast

Abstract Backgrounds With increasing screening for breast cancer, non-palpable breast lesions are detected more frequently. A preoperative localization is very important for a minimal but accurate excision of a non-palpable breast lesion. The purpose of this study was to evaluate the efficacy and safety of indocyanine green(ICG)-hyaluronic acid mixture injection as a novel material for localization. Methods We performed prospective clinical trial with female patients who underwent surgery for non-palpable breast lesion. 44 patients were sequentially assigned to the control group(localization with activated charcoal), test group 1(ICG-hyaluronic acid mixture 0.1ml), or test group 2(ICG-hyaluronic acid mixture 0.2ml) by 1:1:1 ratio. Results Most were over 40 years old, and there were no differences between three groups in age distribution. According to the pathologic results, fibroadenoma accounted for the largest share (38.6%, 17/44) and malignancy accounted for 11.4% (5/44). The marking rate on both breast lesions and excised specimens was over 86% in all groups, and there was no difference. However, skin pigmentation was only in the control group and the accuracy of resection (the greatest length in cm of the excised specimen divided by the greatest length in cm on the pre-operation ultrasound image, the value closer to 1 meant resection as much as the size on ultrasound image) was different significantly. The average was 3.7(range 1.2-13.3) in control group and 2.2 (1.0-4.2) in test 1 group and 2.1(1.0-4.2) in test 2 group. Conclusion ICG-hyaluronic acid mixture injection was superior to activated charcoal for localization in patients with non-palpable breast lesions.

Sign in / Sign up

Export Citation Format

Share Document