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2022 ◽  
Vol 15 (1) ◽  
pp. 52-58
Author(s):  
Rafael Vidal Merola ◽  
◽  
Artur William Veloso ◽  
Alberto Diniz-Filho ◽  
◽  
...  

AIM: To assess intraocular pressure (IOP) during the daily curve of intraocular pressure (DCPo) in keratoconic eyes and compare Goldmann applanation tonometer (GAT), without and with astigmatism correction (nGAT and cGAT) and Tono-Pen AVIA (TPA) assessment methods. METHODS: Thirty-nine keratoconic eyes of 24 patients were assessed. DCPo was evaluated with five IOP measurements; four were performed with a GAT (nGAT and cGAT), and a Tono-Pen AVIA (TPA) at various times throughout the day. RESULTS: Mean IOP DCPo values (mm Hg) were: nGAT, 9.9±2.6; cGAT, 11.3±2.6; TPA 12.3±3.1. Mean IOP DCPo differences (mm Hg) and Spearman's correlation coefficients were as follows: cGATc-nGAT, 1.32±1.31, rs=0.879 (P<0.01); cGAT-TPA, -1.02±2.08, rs=0.723 (P<0.01); and nGAT-TPA, -2.35±2.23, rs=0.730 (P<0.01). Bland-Altman analysis for agreement between cGAT-TPA and nGAT-TPA mean IOP DCPo measurements revealed a mean difference of 1.02 (95%CI, 0.35-1.70) and 2.35 (95%CI, 1.62-3.07) mm Hg, respectively. Regression analysis yielded the following equation: TPA IOP=5.49+0.775×cGAT-0.015×ACD-0.299×corneal astig matism, which allowed us to infer TPA IOP values from other parameters. CONCLUSION: In keratoconic eyes, IOP peaks of DCPo measurements are identified at 6 a.m., independent of the tonometer. The mean DCPo values are: TPA>cGAT>nGAT. IOP TPA measures are predictive of cGAT values, adjusted according to anterior chamber depth and corneal astigmatism.


2022 ◽  
Vol 15 (1) ◽  
pp. 59-64
Author(s):  
Na Liao ◽  
◽  
Guang-Yun Mao ◽  
Fan-Jun Bao ◽  
Zhong Lin ◽  
...  

AIM: To investigate fluctuation of intraocular pressure (IOP) and seasonal variation of 24-hour IOP during one year in healthy participants METHODS: Totally 13 young healthy volunteers participated in this study. IOP was measured with Canon TX-20 at about 8:00-9:00 a.m. from Monday to Friday every week for a whole year. They also underwent 24-hour IOP examination every three months. Blood pressure, heart rate, temperature, humidity, atmosphere pressure, sunshine duration and other environment parameters were recorded. RESULTS: The yearly fluctuation curve showed IOP in the summer months were lower than other seasons. In the multivariable generalized estimating equation analysis, IOP had a negative correlation with both temperature and sunshine duration (P<0.05). There also was a seasonal effect on 24-hour IOP. However, all intraclass correlation coefficients values of minimum, maximum and average of the 24-hour IOP and each individual IOP were less than 0.30. CONCLUSION: IOP is trend to be higher in cold days than warm days. IOP have negative association with both environmental temperature and duration of sunshine. On a season-to-season basis, 24-hour IOP is not highly reproducible in healthy volunteers.


2022 ◽  
Vol 8 ◽  
Author(s):  
Le Li ◽  
Yulong Xiong ◽  
Zhao Hu ◽  
Yan Yao

Objective:The effect of renal denervation (RDN) on heart rate (HR) in patients with hypertension had been investigated in many studies, but the results were inconsistent. This meta-analysis was performed to evaluate the efficacy of RDN on HR control.Methods:Databases, such as PubMed, EMBASE, Cochrane, and ClinicalTrials.gov, were searched until September 2021. Randomized controlled trials (RCTs) or non-RCTs of RDN in hypertensive patients with outcome indicators, such as HR, were selected. Weighted mean difference (WMD) was calculated for evaluating the changes in HR from baseline using fixed-effects or random-effects models. The Spearman's correlation coefficients were used to identify the relationship between the changes of HR and systolic blood pressure (SBP).Results:In the current meta-analysis, 681 subjects from 16 individual studies were included. This study showed that RDN could reduce office HR in patients with hypertension [WMD = −1.93 (95% CI: −3.00 to −0.85, p < 0.001)]. In addition, 24-h HR and daytime HR were decreased after RDN [WMD = −1.73 (95% CI: −3.51 to −0.31, p = 0.017) and −2.67 (95% CI: −5.02 to −0.32, p = 0.026) respectively], but nighttime HR was not significantly influenced by RDN (WMD = −2.08, 95% CI: −4.57 to 0.42, p = 0.103). We found that the reduction of HR was highly related to the decrease of SBP (r = 0.658, p < 0.05).Conclusion:Renal denervation could reduce office, 24-h, and daytime HR, but does not affect nighttime HR. And the effect is highly associated with blood pressure (BP) control.Systematic Review Registration:https://www.crd.york.ac.uk/PROSPERO, identifier: CRD42021283065.


2022 ◽  
Vol 8 ◽  
Author(s):  
Sameh Mosaed ◽  
Andrew K. Smith ◽  
John H. K. Liu ◽  
Donald S. Minckler ◽  
Robert L. Fitzgerald ◽  
...  

BackgroundΔ9-tetrahydrocannabinol (THC) has been shown to decreased intraocular pressure (IOP). This project aims to define the relationship between plasma THC levels and IOP in healthy adult subjects.MethodsEleven healthy subjects received a single dose of inhaled cannabis that was self-administered in negative pressure rooms. Measurements of IOP and plasma THC levels were taken at baseline and every 30 min for 1 h and afterwards every hour for 4 h. IOP reduction and percent change in IOP over time were calculated. Linear regression models were used to measure the relationship between IOP and plasma THC levels. Two line linear regression models with F-tests were used to detect change points in the regression. Then, Pearson correlations were computed based on the change point.ResultsTwenty-two eyes met inclusion criteria. The average peak percentage decrease in IOP was 16% at 60 min. Percent IOP reduction as well as total IOP reduction demonstrated a negative correlation with THC plasma levels showing r-values of −0.81 and −0.70, respectively. F-tests revealed a change point in the regression for plasma levels >20 ng/ml. For levels >20 ng/ml, the correlation coefficients changed significantly with r-values of 0.21 and 0.29 (p < 0.01).ConclusionPlasma THC levels are significantly correlated with IOP reduction up to plasma levels of 20 ng/ml. Plasma levels >20 ng/ml were not correlated with further decrease in IOP. More research is needed to determine the efficacy of THC in reducing IOP for eyes with ocular hypertension and glaucoma.


2022 ◽  
pp. 105381512110695
Author(s):  
Mackenzie K. Martin ◽  
Patricia A. Snyder ◽  
Brian Reichow ◽  
Crystal D. Bishop

The purpose of this study was to examine the comparability of counts of embedded instruction learning trials when different methods of viewing and recording direct behavioral observations were used. In 13 classrooms, while videotaping embedded instruction implementation for a larger randomized controlled efficacy trial was occurring, teachers’ implementation of trials was coded in situ using pencil-and-paper methods. Videos were later coded using computer-assisted methods. Dependent-samples t tests, Pearson product-moment correlation coefficients, and additional score agreement calculations were conducted. Statistically significant differences were found in the estimates of trial frequency. Correlational analyses showed positive and strong relationships between the coding methods. Coding agreement was higher across the entire observation versus during 10-min continuous event blocks. In situ coding took significantly less time than video coding. Results provide empirical evidence for the advantages and disadvantages of common viewing and recording methods for quantifying behavior as part of systematic observation systems.


Author(s):  
Jina Yang ◽  
Kon Hee Kim

In this descriptive study, we aimed to identify factors related to emergency room nurses’ disaster triage ability. A total of 166 nurses who worked for emergency departments of general hospitals completed a structured questionnaire consisting of the Disaster Triage Ability Scale (DTAS), the Strategic Thinking Scale (STS), the Problem-Solving Inventory (PSI), and the Original Grit Scale (Grit-O). The data were analyzed using SPSS/WIN 25.0 by means of descriptive statistics, t-test, one-way ANOVA, the Scheffé post hoc test, Pearson’s correlation coefficients, and stepwise multiple regression. Participants’ DTAS averaged 14.03 ± 4.28 (Range 0–20) and showed a statistically significant difference according to their experience of triage education (t = 2.26, p = 0.022) as a disaster triage-related attribute. There were significant correlations among DTAS and confidence in the PSI (r = 0.30, p < 0.001), the approach-avoidance style in the PSI (r = −0.28, p < 0.001), and futurism in the STS (r = 0.19, p = 0.019). The strongest predictor was confidence in the PSI; in addition, 14.1% of the DTAS was explained by confidence in the PSI, approach-avoidance in the PSI, and futurism in the STS. Emergency room nurses who received triage education showed a higher level of the DTAS and their DTAS could be explained by problem-solving skills and strategic thinking. Therefore, it is necessary to develop and implement triage education programs integrated with stress management to improve the approach-avoidance style to ensure better problem-solving skills and to utilize various training methods to enhance confidence to improve problem-solving skills and futurism as part of strategic thinking.


Author(s):  
Waleed Abdualaziz Mohammad Dahag ◽  
Abdulwahab Ismail Mohamed Al-Kholani ◽  
Taghreed Ahmed M Al-Kibsi ◽  
Hussein Shoga Al-Deen ◽  
Hassan Abdulwahab Al-Shamahy ◽  
...  

Introduction and objective: Mixed dentition space analysis methods via Tanaka-Johnston analysis are regularly used all over the world. Conversely, the appropriate of this analysis between different ethnic groups is dubious. The study aimed to test the appropriate of the Tanaka-Johnston analysis for Yemeni adults and to arise regression equations designed for Yemen population if needed.  Methods: The study included two hundred and twenty-seven (106 males and 121 females) Yemenis from Sana'a University, University of Science and Technology, and Al-Rehab Private Clinic. The mesiodistal widths of the four permanent lower canines, incisors, and premolars for the entire quadrants were determined with a digital caliper to the nearest 0.01 mm. To compare average presentation values ​​derived from this study with values ​​derived using Tanaka-Johnston equations, Student's paired t-test was used, as well as the chi-square (χ2) test used for appropriateness of fit. Result: Gender differences were observed in the total mesiodistal width of both canines and premolars in both arches as revealed by the t-test (p < 0.001). The sum of the actual mesiodistal width of the canines and premolars was compared with the expected widths derived from the Tanaka and Johnston equation and significant differences (p<0.001) were found. Regression analysis indicated that the sum of the mesiodistal width of the permanent mandibular incisors is a good predictor of that of un-erupted canines and premolars, with correlation coefficients ranging from 0.51 to 0.61. Accordingly, two linear regression equations were developed to predict tooth width for Yemeni males and females. Conclusion: It was concluded from this study that the Tanaka-Johnston analysis did not accurately predict the mesiodistal width of the unruptured canines and premolars of the Yemeni population. Moreover, new regression equations have been developed for the research sample that can be a standard for Yemen. However, further studies must be performed to verify the applicability and accuracy of these equations.                   Peer Review History: Received: 10 November 2021; Revised: 12 December; Accepted: 29 December, Available online: 15 January 2022 Academic Editor: Dr. Asia Selman Abdullah, Pharmacy institute, University of Basrah, Iraq, [email protected] UJPR follows the most transparent and toughest ‘Advanced OPEN peer review’ system. The identity of the authors and, reviewers will be known to each other. This transparent process will help to eradicate any possible malicious/purposeful interference by any person (publishing staff, reviewer, editor, author, etc) during peer review. As a result of this unique system, all reviewers will get their due recognition and respect, once their names are published in the papers. We expect that, by publishing peer review reports with published papers, will be helpful to many authors for drafting their article according to the specifications. Auhors will remove any error of their article and they will improve their article(s) according to the previous reports displayed with published article(s). The main purpose of it is ‘to improve the quality of a candidate manuscript’. Our reviewers check the ‘strength and weakness of a manuscript honestly’. There will increase in the perfection, and transparency.  Received file:                Reviewer's Comments: Average Peer review marks at initial stage: 6.5/10 Average Peer review marks at publication stage: 7.5/10 Reviewers: Dr. A.A. Mgbahurike, University of Port Harcourt, Nigeria, [email protected] Rola Jadallah, Arab American University, Palestine, [email protected] Similar Articles: PREVALENCE AND CAUSES OF TRAUMATIC DENTAL INJURIES TO ANTERIOR TEETH AMONG PRIMARY SCHOOL CHILDREN IN SANA'A CITY, YEMEN OCCLUSAL CHARACTERISTICS OF THE PRIMARY DENTITION AMONG A SAMPLE OF YEMENI PRE-SCHOOL CHILDREN


2022 ◽  
Vol 2022 ◽  
pp. 1-13
Author(s):  
Beulah M ◽  
MR Sudhir ◽  
Shenen Chen ◽  
Sasha Rai ◽  
Deekshith Jain

Numerous works are reported in literature regarding the enhancement of compressive strength of fly ash-GGBS geopolymer combinations with addition of alkali activators of varying concentrations. However, a limited study has been chronicled, revealing the specific role of alkali or alkaline earth contributed by the fly ash-GGBS combinations on the compressive strength development. It is well known that the strength of a geopolymer is dependent on gel formation from Al/Si ratio, Ca/Si ratio, and Ca/(Si + Al) ratio but their exact role when cured for various extended periods is unknown as yet. In the present study, alkali concentration in a fly ash-GGBS geopolymer combination was varied from 6 M to 12 M with increments of two mol in six different fly ash-GGBS combinations with a minimum of 20 percent and a maximum of 70 percent GGBS. The correlation coefficients between compressive strength and Al/Si, Ca/Si, and Ca/(Si + Al) ratios exhibited values higher than 0.95 taken individually. Multiple linear regression analysis with compressive strength (as dependent parameter) and individual values of Al/Si, Ca/Si, and Ca/(Si + Al) ratios (as independent parameters) was effectuated. It was observed that, depending on the composition, the compressive strength circumstantiated a changeover from Ca/Si to Ca/(Si + Al) ratio in the intermediate composition range. Such a detailed analysis is considered supportive of developing a suitable composition which will provide the optimum compressive strength of the combination.


2022 ◽  
Author(s):  
Otilia-Maria Bordeianu ◽  
◽  
Claudia-Elena Grigoras-Ichim ◽  
Lucia Morosan-Danila ◽  
◽  
...  

The global crisis generated by the COVID-19 pandemic among the population and at the level of companies, state institutions, etc., underlined the importance of analysing its impact at different levels (intern, national and international level). The concepts of sustainability, development and growth must be aware, adapted and implemented more and more frequently, even constantly, in order to cope with the current evolution of the economy (and not only). The paper is an empirical research conducted in the North-East Region of Romania, aiming to analyse the impact of COVID-19 on local companies (especially SME’s), in the context of existing correlation between the COVID-19 impact on resizing, restricting, changing the number of active employees, changing revenue, changing turnover and changing profit, based on the Spearman correlation coefficients. In this sense, it was important to implement sustainability strategies and ensure the activity and resources of companies in the long term, because the effects of an economic crisis (natural resources, human resources, not only financial) are felt in 2021 and will be felt in the future 10 years. The paper concludes with two practical solutions to ensure the sustainability of the companies involved in the study, solutions that can be applied by all companies that have been affected by the COVID-19 pandemic.


2022 ◽  
Author(s):  
Qingtang Zhu ◽  
Jingyuan Fan ◽  
Fanbin Gu ◽  
Lulu Lv ◽  
Zhejin Zhang ◽  
...  

Abstract Background: Range of motion (ROM) measurements are essential for diagnosing and evaluating upper extremity conditions. Clinical goniometry is the most commonly used methods but it is time-consuming and skill-demanding. Recent advances in human tracking algorithm suggest potential for automatic angle measuring from RGB images. It provides an attractive alternative for at-distance measuring. However, the reliability of this method has not been fully established. The purpose of this study is to evaluate if the results of algorithm are as reliable as human raters in upper limb movements.Methods: Thirty healthy young adults (20 males, 10 females) participated in this study. Participants were asked to performed a 6-motion task including movement of shoulder, elbow and wrist. Images of movements were capture by commercial digital camera. Each movement was measured by a pose tracking algorithm and compared with the surgeon-measurement results. The mean differences between the two measurements were compared. Pearson correlation coefficients were used to determine the relationship. Reliability was investigated by the intra-class correlation coefficients.Results: Comparing this algorithm-based method with manual measurement, the mean differences were less than 3 degrees in 5 motions (shoulder abduction: 0.51; shoulder elevation: 2.87; elbow flexion:0.38; elbow extension:0.65; wrist extension: 0.78) except wrist flexion. All the intra-class correlation coefficients were larger than 0.60. The Pearson coefficients also showed high correlations between the two measurements (p<0.001). Conclusions: Our results indicated that pose estimation is a reliable method to measure the shoulder and elbow angles, supporting RGB images for measuring joint ROM. Our results proved the possibility that patients can assess their ROM by photos taken by a digital camera.Trial registration: This study was registered in the Clinical Trials Center of The First Affiliated Hospital, Sun Yat-sen University (2021-387).


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