Decrease in alpha-fetoprotein levels predicts reduced incidence of hepatocellular carcinoma in patients with hepatitis C virus infection receiving interferon therapy: a single center study

2011 ◽  
Vol 47 (4) ◽  
pp. 444-451 ◽  
Author(s):  
Yukio Osaki ◽  
Yoshihide Ueda ◽  
Hiroyuki Marusawa ◽  
Jun Nakajima ◽  
Toru Kimura ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Hepatitis C Virus ◽  
Hepatitis C ◽  
Virus Infection ◽  
Interferon Therapy ◽  
Alpha Fetoprotein ◽  
Hepatitis C Virus Infection ◽  
Single Center ◽  
Single Center Study ◽  
Center Study

scholarly journals Occult Hepatitis C Virus Infection in Hemodialysis Patients; Single Center Study

10.19082/1619 ◽  
2015 ◽  
Vol 7 (8) ◽  
pp. 1619-1625 ◽  
Author(s):  
Samya El-shishtawy ◽  
Nevine Sherif ◽  
Emad Abdallh ◽  
Laila Kamel ◽  
Mohamed Abbas ◽  
...  
Keyword(s):  
Hepatitis C Virus ◽  
Hepatitis C ◽  
Virus Infection ◽  
Hemodialysis Patients ◽  
Hepatitis C Virus Infection ◽  
Single Center ◽  
Occult Hepatitis ◽  
Single Center Study ◽  
Occult Hepatitis C ◽  
Center Study

Effect of interferon therapy on serum alpha-fetoprotein levels in patients with chronic hepatitis C virus infection

1998 ◽  
Vol 59 (4) ◽  
pp. 223-226
Author(s):  
Roberto Franceschini ◽  
Antonio Picciotto ◽  
Angelo Cataldi ◽  
Giovanni Corsini ◽  
Nicoletta Sinelli ◽  
...  
Keyword(s):  
Chronic Hepatitis ◽  
Hepatitis C Virus ◽  
Hepatitis C ◽  
Virus Infection ◽  
Chronic Hepatitis C ◽  
Interferon Therapy ◽  
Alpha Fetoprotein ◽  
Hepatitis C Virus Infection ◽  
Chronic Hepatitis C Virus ◽  
Serum Alpha Fetoprotein

scholarly journals Hepatocellular carcinoma in patients with chronic hepatitis C: Experience gained at Clinical Center of Vojvodina

2014 ◽  
Vol 67 (suppl. 2) ◽  
pp. 31-38
Author(s):  
Maja Ruzic ◽  
Milotka Fabri ◽  
Tomislav Preveden ◽  
Sanja Stojanovic ◽  
Zoran Milosevic ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Liver Cirrhosis ◽  
Chronic Hepatitis ◽  
Hepatitis C Virus ◽  
Hepatitis C ◽  
Virus Infection ◽  
Chronic Hepatitis C ◽  
Alpha Fetoprotein ◽  
Focal Lesion ◽  
Hepatitis C Virus Infection

Introduction. The incidence of chronic hepatitis C and its consequences, liver cirrhosis and hepatocellular carcinoma is growing rapidly. The aim of this study was to evaluate clinical characteristics of patients with hepatocellular carcinoma and chronic hepatitis C treated at the Clinical Centre of Vojvodina and therapy options. Material and Methods. This retrospective study included 51 patients (52.9% male and 47.1% female) with chronic hepatitis C and hepatocellular carcinoma treated between 2000 and 2014. The average age of patients was 61.6 years (SD=10.8) and the average duration of hepatitis C virus infection was 30.2 years (SD=11.7). All patients had liver cirrhosis and 43.1% had previously been treated with pegylated interferon and ribavirin. According to the Barcelona Clinic Liver Cancer criteria, stadium A, B, C and D were found in 15.7%, 52.3%, 19.6% and 11.8% of the patients, respectively. The average value of alpha fetoprotein at the moment of making diagnosis of hepatocellular carcinoma was 397.56 ng/ml and the level of alpha fetoprotein was below 20mg/ml in 26% of patients. Tumor resection, radiofrequency ablation, chemoembolization, systemic chemotherapy and liver transplantation were performed in 13.7%, 3.9%, 1.9%, 1.9% and 5.9% of patients, respectively. Average survival time after the diagnosis of hepatocellular carcinoma among patients included in the study was 1.39 (SD=1.61) years. Conclusion. Ultrasound examinations of the patients with liver cirrhosis caused by hepatitis C virus infection are obligatory every 3 months. Etiology of every focal lesion in the liver must be clarified, which could increase the possibility of administration of available therapeutic methods.

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