Preventive effects of propofol and ketamine on renal injury in unilateral ureteral obstruction

2010 ◽  
Vol 24 (1) ◽  
pp. 73-80 ◽  
Author(s):  
Bayazit Dikmen ◽  
Hatice Yagmurdur ◽  
Turgay Akgul ◽  
Muzeyyen Astarci ◽  
Huseyin Ustun ◽  
...  
2000 ◽  
Vol 163 (6) ◽  
pp. 1904-1907 ◽  
Author(s):  
HIEP-THIEU NGUYEN ◽  
HSI-YANG WU ◽  
LAURENCE S. BASKIN ◽  
BARRY A. KOGAN

2010 ◽  
Vol 183 (4) ◽  
pp. 1630-1635 ◽  
Author(s):  
Keiichi Ito ◽  
Hidehiko Yoshii ◽  
Takako Asano ◽  
Kaori Seta ◽  
Yasunori Mizuguchi ◽  
...  

2010 ◽  
Vol 298 (4) ◽  
pp. F1024-F1032 ◽  
Author(s):  
Tipu S. Puri ◽  
Mohammed I. Shakaib ◽  
Anthony Chang ◽  
Liby Mathew ◽  
Oladunni Olayinka ◽  
...  

Chronic kidney disease (CKD) begins with renal injury; the progression thereafter depends upon a number of factors, including genetic background. Unilateral ureteral obstruction (UUO) is a well-described model of renal fibrosis and as such is considered a model of CKD. We used an improved reversible unilateral ureteral obstruction (rUUO) model in mice to study the strain dependence of development of CKD after obstruction-mediated injury. C57BL/6 mice developed CKD after reversal of three or more days of ureteral obstruction as assessed by blood urea nitrogen (BUN) measurements (>40 mg/dl). In contrast, BALB/c mice were resistant to CKD with up to 10 days ureteral obstruction. During rUUO, C57BL/6 mice exhibited pronounced inflammatory and intrinsic proliferative cellular responses, disruption of renal architecture, and ultimately fibrosis. By comparison, BALB/c mice had more controlled and measured extrinsic and intrinsic responses to injury with a return to normal within several weeks after release of ureteral obstruction. Our findings provide a model that allows investigation of the genetic basis of events during recovery from injury that contribute to the development of CKD.


2013 ◽  
Vol 17 (2) ◽  
pp. 447-452 ◽  
Author(s):  
Bo Xu ◽  
Yu-bo Zhang ◽  
Zhao-zhu Li ◽  
Mo-wen Yang ◽  
Shuai Wang ◽  
...  

2015 ◽  
Vol 41 (6) ◽  
pp. 1185-1193 ◽  
Author(s):  
Murat Dursun ◽  
Alper Otunctemur ◽  
Emin Ozbek ◽  
Suleyman Sahin ◽  
Huseyin Besiroglu ◽  
...  

2017 ◽  
Vol 32 (suppl_3) ◽  
pp. iii518-iii518
Author(s):  
Jin Joo Cha ◽  
Hye Sook Min ◽  
Jung Yeon Ghee ◽  
Ji Ae Yoo ◽  
Gyusik Choi ◽  
...  

2006 ◽  
Vol 169 (4) ◽  
pp. 1107-1117 ◽  
Author(s):  
Atsuko Kamijo-Ikemori ◽  
Takeshi Sugaya ◽  
Ayako Obama ◽  
Junya Hiroi ◽  
Hiroshi Miura ◽  
...  

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