Anti-plasmodial, Anti-inflammatory, anti-nociceptive and safety profile of Maytenus senegalensis root bark extract on hepato-renal integrity in experimental animals

2019 ◽  
Vol 28 (6) ◽  
pp. 1571-1579 ◽  
Author(s):  
Sheriff I. Umar ◽  
Muhammad Ndako ◽  
Ali A. Jigam ◽  
Sherifat F. Adefolalu ◽  
Gabriel F. Ibikunle ◽  
...  
Keyword(s):  
Safety Profile ◽  
Bark Extract ◽  
Root Bark ◽  
Experimental Animals ◽  
Maytenus Senegalensis ◽  
Anti Inflammatory

scholarly journals Phytochemistry and anti-inflammatory activity of ethanolic root bark extract of Vepris nobilis Mziray (Rutaceae family)

2020 ◽  
Vol 9 ◽  
pp. e00484
Author(s):  
Francis Omujal ◽  
Kibira Irene Tenda ◽  
Stephen Lutoti ◽  
Irene Kirabo ◽  
Simon Dembe Kasango ◽  
...  
Keyword(s):  
Inflammatory Activity ◽  
Bark Extract ◽  
Root Bark ◽  
Anti Inflammatory

scholarly journals Antinociceptive, anti-inflammatory and antipyretic effects of ethanolic root bark extract of Icacina senegalensis in rodents

2016 ◽  
pp. 104-108
Author(s):  
Esien David-Oku ◽  
Godwin Akuodor ◽  
Emmanuel Edet ◽  
Godknows Ogbuji ◽  
Juliet Obiajunwa-Otteh ◽  
...  
Keyword(s):  
Bark Extract ◽  
Root Bark ◽  
Anti Inflammatory

scholarly journals Antipyretic, analgesic and anti-inflammatory activities of methanol extract of root bark of Acacia jacquemontii Benth (Fabaceae) in experimental animals

2016 ◽  
Vol 15 (9) ◽  
pp. 1859
Author(s):  
Khuram Ashfaq ◽  
Bashir A. Choudhary ◽  
Muhammad Uzair ◽  
Sajid N. Hussain ◽  
Muhammad A. Ghaffari ◽  
...  
Keyword(s):  
Methanol Extract ◽  
Root Bark ◽  
Experimental Animals ◽  
Anti Inflammatory

scholarly journals Investigation of chronic efficacy and safety profile of two potential anti-inflammatory bipyrazole-based compounds in experimental animals

2018 ◽  
Vol Volume 11 ◽  
pp. 143-153 ◽  
Author(s):  
Souraya Domiati ◽  
Mohammed Mehanna ◽  
Hanan Ragab ◽  
Hania Nakkash Chmaisse ◽  
Ahmed El Mallah
Keyword(s):  
Safety Profile ◽  
Efficacy And Safety ◽  
Experimental Animals ◽  
Anti Inflammatory

EFFECT OF KAGOCEL PREPARATION ON THE GENERATIVE FUNCTION OF EXPERIMENTAL ANIMALS AT ITS ADMINISTRATION IN THE INFANTILE PERIOD OF THEIR DEVELOPMENT

2017 ◽  
pp. 42-49
Author(s):  
T. A. Borovskaya ◽  
M. E. Poluektova ◽  
A. V. Vychuzhanina ◽  
V. A. Mashanova ◽  
Yu. A. Shchemerova
Keyword(s):  
Toxic Effect ◽  
Reproductive System ◽  
Safety Profile ◽  
Therapeutic Dose ◽  
Antiviral Drug ◽  
Experimental Studies ◽  
Reproductive Age ◽  
Pathological Changes ◽  
Pediatric Practice ◽  
Experimental Animals

In experimental studies on rats (males, females) at their infantile stage starting from 10 days, a potential delayed toxic effect of the antiviral drug Kagocel on the reproductive system was studied. The drug was administered for 12 days in a therapeutic dose and at a dose 10-fold higher than the therapeutic one. Reproductive safety was estimated after animals reached the reproductive age (2.5 months). It was found out that the drug, when administered in both doses, does not decrease the fertility of animals, does not induce morphological and pathological changes in the sex glands, and does not have toxic effect on the offspring. Obtained data characterize Kagocel as a preparation with a wide reproductive safety profile and show that it can be used in pediatric practice for infants.

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