Optimization of the time series NDVI-rainfall relationship using linear mixed-effects modeling for the anti-desertification area in the Beijing and Tianjin sandstorm source region

2017 ◽  
Vol 132 (3-4) ◽  
pp. 1291-1301 ◽  
Author(s):  
Jin Wang ◽  
Tao Sun ◽  
Anmin Fu ◽  
Hao Xu ◽  
Xinjie Wang
2019 ◽  
Author(s):  
Andrea Orlandi ◽  
Emily S. Cross ◽  
Guido Orgs

What constitutes a beautiful action? Research into dance aesthetics has largely focussed on subjective features like familiarity with the observed movement but has rarely studied objective features like speed or acceleration. We manipulated the kinematic complexity of observed actions, by creating dance sequences that varied in movement timing, but not in movement trajectory. Dance-naïve participants rated the dance videos on speed, effort, reproducibility, and preference. Using linear mixed-effects modeling, we show that faster movement sequences with varied velocity profiles are judged to be more effortful, less reproducible, and more aesthetically pleasing than slower sequences with uniform velocity profiles. Accordingly, dance aesthetics depend not only on which movement is being performed but on how movements are executed and linked. Accordingly, the aesthetics of movement timing may apply across culturally-specific dance styles and predict both preference for and perceived difficulty of dance, consistent with an effort heuristic account of art appreciation.


2016 ◽  
Vol 12 ◽  
pp. P356-P356
Author(s):  
Akshay Pai ◽  
Stefan Sommer ◽  
Lars Lau Raket ◽  
Lauge Sørensen ◽  
Mads Nielsen

2013 ◽  
Vol 57 (4) ◽  
pp. 1895-1901 ◽  
Author(s):  
Joan M. Korth-Bradley ◽  
Paul C. McGovern ◽  
Joanne Salageanu ◽  
Kyle Matschke ◽  
Anna Plotka ◽  
...  

ABSTRACTWe evaluated the effect of tigecycline (50-mg and 200-mg doses) on corrected QT (QTc) intervals and assessed safety and tolerability in a randomized, placebo-controlled, four-period crossover study of 48 (44 male) healthy volunteers aged 22 to 53 years. Fed subjects received tigecycline (50 mg or 200 mg) or placebo in a blinded fashion or an open-label oral dose of moxifloxacin (400 mg) after 1 liter of intravenous fluid. Serial electrocardiograms were recorded before, and for 96 h after, dosing. Blood samples for tigecycline pharmacokinetics were collected after each recording. QTc intervals were corrected using Fridericia's correction (QTcF). Pharmacokinetic parameters were calculated using noncompartmental methods with potential relationships examined using linear mixed-effects modeling. Adverse events were recorded. The upper limits of the 90% confidence interval for the mean difference between both tigecycline doses and placebo for all time-matched QTcF interval changes from baseline were <5 ms. The tigecycline concentrations initially declined rapidly and then more slowly. In the group given 50 mg of tigecycline, the pharmacokinetic parameters and means were as follows: maximum concentration of drug in serum (Cmax), 432 ng/ml; area under the concentration-time curve from time zero extrapolated to infinity (AUC0–∞), 2,366 ng · h/ml; clearance (CL), 21.1 liters/h; volume of distribution at steady state (Vss), 610 liters; and terminal half-life (t1/2), 22.1 h. Proportional or similar values were found for the group given 200 mg of tigecycline. Linear mixed-effects modeling failed to show an effect on QTcF values by tigecycline concentrations (P= 0.755). Tigecycline does not prolong the QTc interval in healthy subjects. This study has been registered at ClinicalTrials.gov under registration no. NCT01287793.


NeuroImage ◽  
2017 ◽  
Vol 147 ◽  
pp. 825-840 ◽  
Author(s):  
Gang Chen ◽  
Paul A. Taylor ◽  
Yong-Wook Shin ◽  
Richard C. Reynolds ◽  
Robert W. Cox

2019 ◽  
Vol 36 (3) ◽  
pp. 253-272
Author(s):  
Miriam Rainsford ◽  
Matthew A. Palmer ◽  
James D. Sauer

Distinctive stimuli are better recognized than typical stimuli in many domains (e.g., faces, words). Distinctiveness predicts the point of recognition of a melody (Bailes, 2010), and the recognition of unique tones within a melody (Vuvan, Podolak, & Schmuckler, 2014), yet no studies have examined the role of distinctiveness in recognizing whole melodies. We composed a set of novel melodies according to rules that should result in these being perceived as more or less distinctive. Using computational analysis and human ratings by a group of 36 pilot testers, we established a final stimulus set of 96 novel melodies (48 eightnote, 48 sixteen-note), half of which were high and half low in distinctiveness. A separate group of 26 participants completed a recognition test using this stimulus set. Using linear mixed-effects modeling, we found that greater pitch and interval range, wider intervals, varied contour, and ambiguous tonality within a Western diatonic framework predicted human perception of distinctiveness. However, only a wider modal (most frequent) interval predicted correct recognition. Distinctiveness improved recognition performance in both stimulus lengths; however, a significant advantage was only shown for sixteen-note melodies. Thus, the distinctiveness effect as observed across domains generalizes to the recognition of longer, whole melodies.


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