Anti-inflammatory activity of (2E,15E)-2-[1-(2-aminophenyl)ethylidineamino]-N′-[1-(2-aminophenyl)ethylidene]benzoic acid hydrazide (AEBH) and some of its nanoparticles rare earth complexes

2016 ◽  
Vol 147 (11) ◽  
pp. 1893-1902 ◽  
Author(s):  
Nasser Mohammed Hosny ◽  
Yousery E. Sherif
Keyword(s):  
Rare Earth ◽  
Benzoic Acid ◽  
Acid Hydrazide ◽  
Inflammatory Activity ◽  
Rare Earth Complexes ◽  
Anti Inflammatory ◽  
Benzoic Acid Hydrazide

Rare-earth complexes with anti-inflammatory drug sulindac: synthesis, characterization, spectroscopic and in vitro biological studies

2021 ◽  
pp. 120516
Author(s):  
Renan Barrach Guerra ◽  
Diogo Alves Gálico ◽  
Thais Fernanda de Campos Fraga-Silva ◽  
Julia Aguiar ◽  
James Venturini ◽  
...  
Keyword(s):  
Rare Earth ◽  
Rare Earth Complexes ◽  
Inflammatory Drug ◽  
Biological Studies ◽  
Anti Inflammatory

Four-Component Reaction between Trimethyl Phosphite, Aroyl Chlorides and Dialkyl Acetylenedicarboxylate with Benzoic Acid Hydrazide

2011 ◽  
Vol 35 (9) ◽  
pp. 516-518 ◽  
Author(s):  
Alireza Hassanabadi ◽  
Mohammad H. Mosslemin ◽  
Mohammad Anary-Abbasinejad ◽  
Farzaneh Ghazvininejad ◽  
Somayeh Koocheki
Keyword(s):  
Benzoic Acid ◽  
Acid Hydrazide ◽  
Trimethyl Phosphite ◽  
Dialkyl Acetylenedicarboxylate ◽  
Benzoic Acid Hydrazide

scholarly journals IN VITRO ANTI-INFLAMMATORY ACTIVITY OF THE COMPONENTS OF AMOMUM TSAO-KO IN MURINE MACROPHAGE RAW 264.7 CELLS

2018 ◽  
Vol 15 (2) ◽  
pp. 26
Author(s):  
Chun Whan Choi ◽  
Ju Young Shin ◽  
Changon Seo ◽  
Seong Su Hong ◽  
Eun-Kyung Ahn ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Benzoic Acid ◽  
Inflammatory Activity ◽  
Raw 264.7 Cells ◽  
Raw 264.7 ◽  
Dependent Manner ◽  
Murine Macrophage ◽  
Etoh Extract ◽  
Anti Inflammatory

Background: Plants still remain the prime source of drugs for the treatment of inflammation and can provide leads for the development of novel anti-inflammatory agents. Material and methods: An in vitro bioassay guide revealed that the 80% ethanol (EtOH) extract of the whole plant, Amomum tsao-ko (Zingiberaceae), displayed anti-inflammatory activity after assessing its effects on murine macrophage RAW 264.7 cells. Result: Phytochemical study of the 80% EtOH extract of Amomum tsao-ko led to the isolation of eight compounds: 4-hydroxy-3-methoxy-benzoic acid (1), meso-hannokinol (2), (+)-hannokinol (3), coumaric acid (4), 4-hydroxy-benzoic acid (5), (+)-epicatechin (6), (-)-catechin (7), and myrciaphenone A (8). The results indicated that two of the isolated components, (+)-epicatechin (6) and (-)-catechin (7), inhibited the production of nitric oxide (NO) significantly in lipopolysaccharide treated RAW 264.7 cells. Conclusion: LPS-induced interleukin tumor necrosis factor-alpha (TNF-), IL-1β and IL-10 production was also decreased in a dose-dependent manner. In addition, western blot analysis revealed that (+)-epicatechin (6) and (-)-catechin (7) reduced the expression of inducible nitric oxide synthase and inhibited nuclear localization of nuclear factor kappa-B (NF-κB).

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