Classic Adamantinoma with Osteofibrous Dysplasia-like Foci and Secondary Aneurysmal Bone Cyst

2003 ◽  
Vol 6 (2) ◽  
pp. 173-178 ◽  
Author(s):  
Angelica Putnam ◽  
Suzanne Yandow ◽  
Cheryl M. Coffin

Adamantinoma, a rare bone lesion of the tibia and fibula, has two distinct variants, classic adamantinoma and osteofibrous dysplasia-like adamantinoma. Composite lesions have not been described. Aneurysmal bone cyst is a benign cystic lesion which may also occur in the tibia and fibula. We report an unusual case of classic adamantinoma with osteofibrous dysplasia-like areas and foci of secondary aneurysmal bone cyst with prominent giant cells. A lesion was diagnosed in a 17-year-old girl with a 14-year history of a slowly enlarging left tibial mass and increasing deformity. Pathologically, the predominant pattern was classic adamantinoma, with minor foci of osteofibrous dysplasia-like adamantinoma and areas of secondary aneurysmal bone cyst with abundant multinucleated giant cells. We report the clinical, radiologic, and pathologic features of this case, and summarize lesions associated with secondary aneurysmal bone cyst. To our knowledge, the association of adamantinoma with secondary aneurysmal bone cyst has not been previously reported.

2017 ◽  
Vol 141 (6) ◽  
pp. 867-871 ◽  
Author(s):  
Wenqian Chen ◽  
Lisa M. DiFrancesco

Chondroblastoma is a rare primary bone tumor of young people that typically arises in the ends of the long bones. Radiologic investigations show a small, circumscribed, lytic lesion. The tumor is characterized histologically by the proliferation of chondroblasts along with areas of mature cartilage, giant cells, and occasionally, secondary aneurysmal bone cyst formation. Chondroblastoma, however, may also present with atypical features, such as prominent hemosiderin deposition, numerous giant cells, or the presence of a large aneurysmal bone cyst component. Malignant entities such as clear cell chondrosarcoma and chondroblastic osteosarcoma must also be considered. Recently, immunohistochemical stains such as DOG1 and SOX9 have been described in chondroblastoma, and K36M mutations in either the H3F3A or H3F3B genes have also been identified. While generally regarded as a benign entity, chondroblastoma manifests an intermediate type of behavior, given its ability to recur locally, and rarely, metastasize.


2001 ◽  
Vol 125 (5) ◽  
pp. 673-676
Author(s):  
Duilio Della Libera ◽  
Gillian Redlich ◽  
Lucia Bittesini ◽  
Giovanni Falconieri

Abstract We report a new case of aneurysmal bone cyst of the larynx occurring in a 22-year-old man. The lesion manifested with progressive breathing discomfort and appeared as a polypoid pedunculated mass attached to the subglottic mucosa. Microscopically, it featured numerous mononuclear and multinucleated giant cells surrounding cavernous spaces filled with blood. Foci of proliferating spindle cells and mature osteoid tissue could be recognized. There was no apparent relationship with the cricoid perichondrium. Clinical follow-up was negative for local recurrence. Based on this report and a review of the literature, we conclude that aneurysmal bone cyst of the larynx is phenotypically comparable to its bone homologue; however, its microscopic recognition may be difficult, especially on small biopsy fragments. Since it can be confused with several lesions, including telangiectatic osteosarcoma, awareness of this rare appearance of aneurysmal bone cyst is important to avoid unnecessary radical surgery.


2011 ◽  
Vol 18 (6) ◽  
pp. 857-860 ◽  
Author(s):  
Christopher J. Stapleton ◽  
Brian P. Walcott ◽  
Katy R. Linskey ◽  
Kristopher T. Kahle ◽  
Brian V. Nahed ◽  
...  

Orthopedics ◽  
2000 ◽  
Vol 23 (11) ◽  
pp. 1205-1207
Author(s):  
Stefanos Bandiera ◽  
Patrizia Bacchini ◽  
Franco Bertoni

2021 ◽  
Vol 17 (5) ◽  
pp. 471-474
Author(s):  
Federica Canzano ◽  
◽  
Ermanno Giombelli ◽  
Davide Cerasti ◽  
Domenico Corradi ◽  
...  

2018 ◽  
Vol 6 (2) ◽  
pp. 86
Author(s):  
Hyun-Seok Lee ◽  
Young-Cho Koh ◽  
Hong Gee Roh ◽  
Hyung Kyu Park ◽  
Soo Yeon Kim

Rare Tumors ◽  
2013 ◽  
Vol 5 (3) ◽  
pp. 146-148 ◽  
Author(s):  
Kato Tomoyuki ◽  
Michiro Susa ◽  
Robert Nakayama ◽  
Itsuo Watanabe ◽  
Keisuke Horiuchi ◽  
...  

2018 ◽  
Vol 4 (1) ◽  
pp. 38-40
Author(s):  
Sundeep Chowdhry ◽  
Prashansa Jaiswal ◽  
Tapan Kumar Dhali ◽  
Akhilesh Shukla

A 3 year old girl presented with a two- day history of multiple fluid filled lesions on buttocks and back of left thigh. As informed by the child's mother, she had fever 4 days back and was irritable with pain and discomfort on back of the left thigh. The pain was episodic and radiated from buttocks to the leg. On examination, multiple fluid filled lesions of various sizes with surrounding erythema were present involving the S1, S2, S3 dermatomes extending from buttock to the sole sparing few areas in between the vesicles. On further examination of whole body, there were multiple discrete fluid filled lesions on erythematous base ranging from 0.1 to 0.3 mm diameter in size on chest, abdomen and back. Multinucleated giant cells with acantholytic cells were found in Tzank smears. Diagnosis of concurrent varicella with herpes zoster was made.Journal of Universal College of Medical Sciences (2016) Vol.04 No.01 Issue 13, Page: 38-40


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