Durable remission of HIV-negative, Kaposi’s sarcoma herpes virus-associated multicentric Castleman disease in patient with rheumatoid arthritis treated with methotrexate

2006 ◽  
Vol 26 (7) ◽  
pp. 1148-1150 ◽  
Author(s):  
Samuel A. Jacobs ◽  
Nicholas Vidnovic ◽  
Hitendra Patel ◽  
Lorinda A. Soma ◽  
Yuan Chang ◽  
...  
Keyword(s):  
Rheumatoid Arthritis ◽  
Kaposi's Sarcoma ◽  
Herpes Virus ◽  
Kaposi’S Sarcoma ◽  
Castleman Disease ◽  
Multicentric Castleman Disease ◽  
Herpès Virus ◽  
Durable Remission ◽  
Hiv Negative

MOLECULAR DETECTION OF KAPOSI’S SARCOMA ASSOCIATED VIRUS (HUMAN HERPES VIRUS 8) IN SINO-NASAL CARCINOMA TISSUES

2020 ◽  
Vol 23 (04) ◽  
pp. 286-297
Author(s):  
Hind Hamed Shaker ◽  
Luma Amer Yasir ◽  
Ausama Abed-Alkadum Alajeely ◽  
Saad Hasan Mohammed Ali ◽  
Shakir H. Mohammed Al-Alwany
Keyword(s):  
Kaposi's Sarcoma ◽  
Herpes Virus ◽  
Molecular Detection ◽  
Kaposi’S Sarcoma ◽  
Human Herpes ◽  
Human Herpes Virus 8 ◽  
Human Herpes Virus ◽  
Herpès Virus ◽  
Nasal Carcinoma

Human herpes virus 8 (Kaposi’s sarcoma herpesvirus)

Oral Oncology ◽  
1998 ◽  
Vol 34 (1) ◽  
pp. 5-14 ◽  
Author(s):  
S.R Porter ◽  
L Di Alberti ◽  
N Kumar
Keyword(s):  
Kaposi's Sarcoma ◽  
Herpes Virus ◽  
Kaposi’S Sarcoma ◽  
Human Herpes ◽  
Human Herpes Virus 8 ◽  
Human Herpes Virus ◽  
Herpès Virus

Targeting the PI3K and MAPK pathways to treat Kaposi’s sarcoma-associated herpes virus infection and pathogenesis

2007 ◽  
Vol 11 (5) ◽  
pp. 589-599 ◽  
Author(s):  
Phelps J Lambert ◽  
Aniqa Z Shahrier ◽  
Audy G Whitman ◽  
Ossie F Dyson ◽  
Adrian J Reber ◽  
...  
Keyword(s):  
Virus Infection ◽  
Kaposi's Sarcoma ◽  
Herpes Virus ◽  
Kaposi’S Sarcoma ◽  
Herpes Virus Infection ◽  
Mapk Pathways ◽  
Herpès Virus

Association of human herpes virus with pulmonary Kaposi's sarcoma

The Lancet ◽  
1995 ◽  
Vol 346 (8976) ◽  
pp. 712 ◽  
Author(s):  
Mark Howard ◽  
Nicola Brink ◽  
Robert Miller ◽  
Richard Tedder
Keyword(s):  
Kaposi's Sarcoma ◽  
Herpes Virus ◽  
Kaposi’S Sarcoma ◽  
Human Herpes ◽  
Human Herpes Virus ◽  
Herpès Virus

scholarly journals Kaposi's Sarcoma Associated-Herpes Virus (KSHV) Seroprevalence in Pregnant Women in South Africa

2010 ◽  
Vol 5 (1) ◽  
pp. 14 ◽  
Author(s):  
Babatyi I Malope-Kgokong ◽  
Patrick MacPhail ◽  
Georgina Mbisa ◽  
Edith Ratshikhopa ◽  
Mhairi Maskew ◽  
...  
Keyword(s):  
South Africa ◽  
Pregnant Women ◽  
Kaposi's Sarcoma ◽  
Herpes Virus ◽  
Kaposi’S Sarcoma ◽  
Herpès Virus

scholarly journals The Contribution of Kaposi’s Sarcoma–Associated Herpesvirus to Mortality in Hospitalized Human Immunodeficiency Virus–Infected Patients Being Investigated for Tuberculosis in South Africa

2019 ◽  
Vol 220 (5) ◽  
pp. 841-851 ◽  
Author(s):  
Melissa J Blumenthal ◽  
Charlotte Schutz ◽  
David Barr ◽  
Michael Locketz ◽  
Vickie Marshall ◽  
...  
Keyword(s):  
South Africa ◽  
Human Immunodeficiency Virus ◽  
Kaposi's Sarcoma ◽  
Kaposi’S Sarcoma ◽  
Castleman Disease ◽  
South Africans ◽  
Multicentric Castleman Disease ◽  
Immunodeficiency Virus ◽  
Kaposi's Sarcoma Associated Herpesvirus ◽  
Kaposi’S Sarcoma Associated Herpesvirus

AbstractBackgroundDespite increasing numbers of human immunodeficiency virus (HIV)–infected South Africans receiving antiretroviral therapy (ART), tuberculosis (TB) remains the leading cause of mortality. Approximately 25% of patients treated for TB have microbiologically unconfirmed diagnoses. We assessed whether elevated Kaposi’s sarcoma–associated herpesvirus (KSHV) viral load (VL) contributes to mortality in hospitalized HIV-infected patients investigated for TB.MethodsSix hundred eighty-two HIV-infected patients admitted to Khayelitsha Hospital, South Africa, were recruited, investigated for TB, and followed for 12 weeks. KSHV serostatus, peripheral blood KSHV-VL, and KSHV-associated clinical correlates were evaluated.ResultsMedian CD4 count was 62 (range, 0–526) cells/μL; KSHV seropositivity was 30.7% (95% confidence interval [CI], 27%–34%); 5.8% had detectable KSHV-VL (median, 199.1 [range, 13.4–2.2 × 106] copies/106 cells); 22% died. Elevated KSHV-VL was associated with mortality (adjusted odds ratio, 6.5 [95% CI, 1.3–32.4]) in patients without TB or other microbiologically confirmed coinfections (n = 159). Six patients had “possible KSHV-inflammatory cytokine syndrome” (KICS): 5 died, representing significantly worse survival (P < .0001), and 1 patient was diagnosed with KSHV-associated multicentric Castleman disease at autopsy.ConclusionsGiven the association of mortality with elevated KSHV-VL in critically ill HIV-infected patients with suspected but not microbiologically confirmed TB, KSHV-VL and KICS criteria may guide diagnostic and therapeutic evaluation.

Sign in / Sign up

Export Citation Format

Share Document