Lesional accumulation of CD8+ cells in sciatic nerves of experimental autoimmune neuritis rats

2015 ◽  
Vol 37 (2) ◽  
pp. 199-203
Author(s):  
Zhi-Ming Zhang ◽  
Rongchen Shi ◽  
Hong Chen ◽  
Zhiren Zhang
Keyword(s):  
Experimental Autoimmune Neuritis ◽  
Cd8 Cells ◽  
Sciatic Nerves ◽  
Experimental Autoimmune

Activation of extracellular signal-regulated kinases in the sciatic nerves of rats with experimental autoimmune neuritis

2004 ◽  
Vol 372 (1-2) ◽  
pp. 57-61 ◽  
Author(s):  
Meejung Ahn ◽  
Changjong Moon ◽  
Yongduk Lee ◽  
Chang Sung Koh ◽  
Kuniko Kohyama ◽  
...  
Keyword(s):  
Experimental Autoimmune Neuritis ◽  
Extracellular Signal ◽  
Sciatic Nerves ◽  
Experimental Autoimmune

Upregulation of osteopontin in Schwann cells of the sciatic nerves of Lewis rats with experimental autoimmune neuritis

2004 ◽  
Vol 372 (1-2) ◽  
pp. 137-141 ◽  
Author(s):  
Meejung Ahn ◽  
Yongduk Lee ◽  
Changjong Moon ◽  
Jae-Kwang Jin ◽  
Yoh Matsumoto ◽  
...  
Keyword(s):  
Schwann Cells ◽  
Experimental Autoimmune Neuritis ◽  
Lewis Rats ◽  
Sciatic Nerves ◽  
Experimental Autoimmune

scholarly journals Expression of Interleukin-16 in Sciatic Nerves, Spinal Roots and Spinal Cords of Experimental Autoimmune Neuritis Rats

2009 ◽  
Vol 19 (2) ◽  
pp. 205-213 ◽  
Author(s):  
Zhi-Yuan Zhang ◽  
Zhiren Zhang ◽  
Uwe Fauser ◽  
Hermann J. Schluesener
Keyword(s):  
Experimental Autoimmune Neuritis ◽  
Spinal Roots ◽  
Sciatic Nerves ◽  
Experimental Autoimmune

scholarly journals Effect of 1.25(OH)2D3 on experimental autoimmune neuritis and its mechanism

2021 ◽  
Vol 5 (2.1) ◽  
pp. 42
Author(s):  
Di Nian ◽  
Zhuohan Li ◽  
Junjie Sun ◽  
Peng Shi
Keyword(s):  
Inflammatory Cytokines ◽  
Body Weight Loss ◽  
Clinical Score ◽  
Therapeutic Effects ◽  
Experimental Autoimmune Neuritis ◽  
Transmission Electron ◽  
New Strategy ◽  
Ifn Γ ◽  
Sciatic Nerves ◽  
Experimental Autoimmune

Objective: To study the potential therapeutic effects of active vitamin D3 (1.25(OH)2D3) in the experimental autoimmune neuritis (EAN). Methods: The EAN model was established by actively immunizing Lewis rats with synthetic P0180–199 pepide and Freund’s complete adjuvant. 1.25(OH)2D3 treatment was given, weight change of rats and clinical score were analyzed. HE staining was used to detect the inflammatory cell infiltration of sciatic nerves and demyelination of sciatic nerves was observed by transmission electron microscope (TEM) at the same time. The expressions of inflammatory cytokines IL-17, IL-10, TGF-β, IFN-γ were detected by ELISA, and the expressions of Th17, Treg were examined by RT-PCR. Results: 1.25(OH)2D3 ameliorated body weight loss and myelin lesions. It decreased expressions of inflammatory cytokines IL-17, IFN-γ and RORrt while those of IL-10, TGF-β and FoxP3 were increased. Conclusions: 1.25(OH)2D3 can improve the clinical pathological changes of EAN rats, and the mechanism may be related to the changes of inflammatory cytokines. 1.25(OH)2D3 is expected to become a new strategy for the clinical treatment of GBS/EAN.

Increased phosphorylation of caveolin-1 in the sciatic nerves of Lewis rats with experimental autoimmune neuritis

2007 ◽  
Vol 1137 ◽  
pp. 153-160 ◽  
Author(s):  
Heechul Kim ◽  
Changjong Moon ◽  
Meejung Ahn ◽  
Yoh Matsumoto ◽  
Chang-Sung Koh ◽  
...  
Keyword(s):  
Experimental Autoimmune Neuritis ◽  
Lewis Rats ◽  
Caveolin 1 ◽  
Sciatic Nerves ◽  
Experimental Autoimmune

Immunohistochemical study of caveolin-1 in the sciatic nerves of Lewis rats with experimental autoimmune neuritis

2006 ◽  
Vol 1102 (1) ◽  
pp. 86-91 ◽  
Author(s):  
Meejung Ahn ◽  
Changjong Moon ◽  
Heechul Kim ◽  
Jeeyoung Lee ◽  
Chang Sung Koh ◽  
...  
Keyword(s):  
Immunohistochemical Study ◽  
Experimental Autoimmune Neuritis ◽  
Lewis Rats ◽  
Caveolin 1 ◽  
Sciatic Nerves ◽  
Experimental Autoimmune

Immunolocalization and activation of nuclear factor-κB in the sciatic nerves of rats with experimental autoimmune neuritis

2006 ◽  
Vol 174 (1-2) ◽  
pp. 32-38 ◽  
Author(s):  
M. Laurà ◽  
A. Mazzeo ◽  
M. Aguennouz ◽  
M. Santoro ◽  
M.A. Catania ◽  
...  
Keyword(s):  
Nuclear Factor Κb ◽  
Experimental Autoimmune Neuritis ◽  
Nuclear Factor ◽  
Sciatic Nerves ◽  
Experimental Autoimmune
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